Macrophage migration inhibitory factor as a chaperone inhibiting accumulation of misfolded SOD1. - Wikidata - wikimedia - TriplyDB

Macrophage migration inhibitory factor as a chaperone inhibiting accumulation of misfolded SOD1.

Macrophage migration inhibitory factor as a chaperone inhibiting accumulation of misfolded SOD1.

http://www.wikidata.org/entity/Q35365484

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Diversity and Inter-Connections in the CXCR4 Chemokine Receptor/Ligand Family: Molecular Perspectives SOD1 misplacing and mitochondrial dysfunction in amyotrophic lateral sclerosis pathogenesis Major histocompatibility complex class I molecules protect motor neurons from astrocyte-induced toxicity in amyotrophic lateral sclerosis.Mutant TDP-43 within motor neurons drives disease onset but not progression in amyotrophic lateral sclerosis.MIF, a controversial cytokine: a review of structural features, challenges, and opportunities for drug development.Translational profiling identifies a cascade of damage initiated in motor neurons and spreading to glia in mutant SOD1-mediated ALS.Reverse engineering human neurodegenerative disease using pluripotent stem cell technology.ALS-linked misfolded SOD1 species have divergent impacts on mitochondria.Endogenous macrophage migration inhibitory factor reduces the accumulation and toxicity of misfolded SOD1 in a mouse model of ALS.HSPB1 mutations causing hereditary neuropathy in humans disrupt non-cell autonomous protection of motor neurons.Non-neuronal Cells in ALS: Role of Glial, Immune cells and Blood-CNS Barriers.A Phosphomimetic Mutation Stabilizes SOD1 and Rescues Cell Viability in the Context of an ALS-Associated Mutation.Simultaneous Multiplexed Measurement of RNA and Proteins in Single Cells.Motoneuron Disease: Basic Science.Macrophage migration inhibitory factor as a component of selective vulnerability of motor neurons in ALS.Epigenetic changes in T-cell and monocyte signatures and production of neurotoxic cytokines in ALS patients.Functional characterization of zebrafish orthologs of the human Beta 3-Glucosyltransferase B3GLCT gene mutated in Peters Plus Syndrome.Misfolded SOD1 is not a primary component of sporadic ALS.Proteinopathies and OXPHOS dysfunction in neurodegenerative diseases.Pathological hydrogen peroxide triggers the fibrillization of wild-type SOD1 via sulfenic acid modification of Cys-111.A computational combinatorial approach identifies a protein inhibitor of superoxide dismutase 1 misfolding, aggregation, and cytotoxicity.MIF inhibits the formation and toxicity of misfolded SOD1 amyloid aggregates: implications for familial ALS.Discovery of Novel Inhibitors of the Tautomerase Activity of Macrophage Migration Inhibitory Factor (MIF).Differential induction of mutant SOD1 misfolding and aggregation by tau and α-synuclein pathology.Macrophage migration inhibitory factor is required for NLRP3 inflammasome activation.Safety and efficacy of human embryonic stem cell-derived astrocytes following intrathecal transplantation in SOD1G93A and NSG animal models.

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Macrophage migration inhibitory factor as a chaperone inhibiting accumulation of misfolded SOD1.

http://www.wikidata.org/entity/Q35365484

description

2015 nî lūn-bûn

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2015 թուականի Մարտին հրատարակուած գիտական յօդուած

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2015 թվականի մարտին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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Macrophage migration inhibitor ...... ccumulation of misfolded SOD1.

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Macrophage migration inhibitor ...... ccumulation of misfolded SOD1.

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Macrophage migration inhibitor ...... ccumulation of misfolded SOD1.

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Macrophage migration inhibitor ...... accumulation of misfolded SOD1

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Anh Bui

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Brian K Kaspar

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Dara Ditsworth

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Guy Zoltsman

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Jason Liang

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Marcus Maldonado

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Martin Marsala

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Melissa McAlonis-Downes

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Michael Navarro

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Salah Abu-Hamad

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P2860

Prion-like propagation of mutant superoxide dismutase-1 misfolding in neuronal cells

Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis

Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model

A Novel Allosteric Inhibitor of Macrophage Migration Inhibitory Factor (MIF)

Molecular basis of nitrate uptake by the plant nitrate transporter NRT1.1

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

Macrophage migration inhibitory factor: a regulator of innate immunity

Protein-binding assays in biological liquids using microscale thermophoresis

Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons

Neuronal matrix metalloproteinase-9 is a determinant of selective neurodegeneration

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1

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Adrian Israelson

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2015-03-19T00:00:00Z

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25801706

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molecular chaperones

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4393372

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