Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma. - Wikidata - wikimedia - TriplyDB

Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma.

Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma.

http://www.wikidata.org/entity/Q35369888

about

Targeting inflammation in pancreatic cancer: Clinical translation Tumor-Associated Macrophages and Neutrophils in Tumor Microenvironment Ion channels and transporters in tumour cell migration and invasion Harnessing the genome for characterization of G-protein coupled receptors in cancer pathogenesis Genetically engineered mouse models of pancreatic adenocarcinoma Regulation of pancreatic function by connective tissue growth factor (CTGF, CCN2)Tumor stroma as targets for cancer therapy CXCR2: a target for pancreatic cancer treatment?Human correlates of provocative questions in pancreatic pathology Exploiting inflammation for therapeutic gain in pancreatic cancer Met receptor tyrosine kinase signaling induces secretion of the angiogenic chemokine interleukin-8/CXCL8 in pancreatic cancer Neutrophils and Granulocytic MDSC: The Janus God of Cancer Immunotherapy Immune checkpoint and inflammation as therapeutic targets in pancreatic carcinoma Targeted destruction of the orchestration of the pancreatic stroma and tumor cells in pancreatic cancer cases: molecular basis for therapeutic implications Attenuated transforming growth factor beta signaling promotes metastasis in a model of HER2 mammary carcinogenesis Asporin Is a Fibroblast-Derived TGF-β1 Inhibitor and a Tumor Suppressor Associated with Good Prognosis in Breast Cancer CXCR2 signaling regulates KRAS(G¹²D)-induced autocrine growth of pancreatic cancer.Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression.CCL9 Induced by TGFβ Signaling in Myeloid Cells Enhances Tumor Cell Survival in the Premetastatic Organ.The roles of TGFβ in the tumour microenvironment.Inflammation and Epithelial-Mesenchymal Transition in Pancreatic Ductal Adenocarcinoma: Fighting Against Multiple Opponents Clinicopathologic significance of the CXCL1-CXCR2 axis in the tumor microenvironment of gastric carcinoma.Pancreatic biomarkers: could they be the answer?Platelets guide the formation of early metastatic niches.Pancreatic cancer and its stroma: a conspiracy theory Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy.Control of CXCR2 activity through its ubiquitination on K327 residue.Inflammation-mediated genetic and epigenetic alterations drive cancer development in the neighboring epithelium upon stromal abrogation of TGF-β signaling.TGFβ signaling in myeloid cells regulates mammary carcinoma cell invasion through fibroblast interactions Macrophage polarization in pancreatic carcinoma: role of heparanase enzyme.Inflammation and pancreatic cancer: molecular and functional interactions between S100A8, S100A9, NT-S100A8 and TGFβ1 Secretome analysis of an osteogenic prostate tumor identifies complex signaling networks mediating cross-talk of cancer and stromal cells within the tumor microenvironment Disruption of STAT3 signalling promotes KRAS-induced lung tumorigenesis Overexpression of chemokine receptor CXCR2 and ligand CXCL7 in liver metastases from colon cancer is correlated to shorter disease-free and overall survival.Role of IL-6 in the resolution of pancreatitis in obese mice CXCR2 Inhibition Profoundly Suppresses Metastases and Augments Immunotherapy in Pancreatic Ductal Adenocarcinoma.Deletion of TGF-β signaling in myeloid cells enhances their anti-tumorigenic properties.Inhibition of CXCR2 profoundly suppresses inflammation-driven and spontaneous tumorigenesis.PYK2 integrates growth factor and cytokine receptors signaling and potentiates breast cancer invasion via a positive feedback loop.A CXCL1 paracrine network links cancer chemoresistance and metastasis

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P2860

Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma.

http://www.wikidata.org/entity/Q35369888

description

2011 nî lūn-bûn

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2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Inhibiting Cxcr2 disrupts tumo ...... creatic ductal adenocarcinoma.

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Inhibiting Cxcr2 disrupts tumo ...... creatic ductal adenocarcinoma.

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type

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Inhibiting Cxcr2 disrupts tumo ...... creatic ductal adenocarcinoma.

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Inhibiting Cxcr2 disrupts tumo ...... creatic ductal adenocarcinoma.

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prefLabel

Inhibiting Cxcr2 disrupts tumo ...... creatic ductal adenocarcinoma.

@ast

Inhibiting Cxcr2 disrupts tumo ...... creatic ductal adenocarcinoma.

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Inhibiting Cxcr2 disrupts tumo ...... creatic ductal adenocarcinoma.

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Agnieszka E Gorska

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Anna Chytil

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Christopher V E Wright

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Dai Mohri

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Hideaki Ijichi

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Keisuke Tateishi

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Koji Miyabayashi

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Mary E Aakre

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Masao Omata

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Motohisa Tada

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P2860

Kras(G12D) and Smad4/Dpc4 haploinsufficiency cooperate to induce mucinous cystic neoplasms and invasive adenocarcinoma of the pancreas

The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

Induction by transforming growth factor-beta1 of epithelial to mesenchymal transition is a rare event in vitro

Effect of conditional knockout of the type II TGF-beta receptor gene in mammary epithelia on mammary gland development and polyomavirus middle T antigen induced tumor formation and metastasis

Macrophages: Obligate Partners for Tumor Cell Migration, Invasion, and Metastasis

Cancer statistics, 2007

Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer

Fibroblasts in cancer

Tumour-educated macrophages promote tumour progression and metastasis

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4106-4117

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10.1172/JCI42754

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10

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121

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Harold L. Moses

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21926469

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