Spinster homolog 2 (spns2) deficiency causes early onset progressive hearing loss. - Wikidata - wikimedia - TriplyDB

Spinster homolog 2 (spns2) deficiency causes early onset progressive hearing loss.

Spinster homolog 2 (spns2) deficiency causes early onset progressive hearing loss.

http://www.wikidata.org/entity/Q35377676

about

Trafficking and Functions of Bioactive Sphingolipids: Lessons from Cells and Model Membranes Sphingosine 1-phosphate signaling pathway in inner ear biology. New therapeutic strategies for hearing loss?Wbp2 is required for normal glutamatergic synapses in the cochlea and is crucial for hearing.Vascular and Immunobiology of the Circulatory Sphingosine 1-Phosphate Gradient.Intracellular sphingosine kinase 2-derived sphingosine-1-phosphate mediates epidermal growth factor-induced ezrin-radixin-moesin phosphorylation and cancer cell invasion.Spinster 2, a sphingosine-1-phosphate transporter, plays a critical role in inflammatory and autoimmune diseases.Sphingosine 1-phosphate receptor 2 (S1P2) attenuates reactive oxygen species formation and inhibits cell death: implications for otoprotective therapy S1PR2 variants associated with auditory function in humans and endocochlear potential decline in mouse.Sphingosine kinase-1, S1P transporter spinster homolog 2 and S1P2 mRNA expressions are increased in liver with advanced fibrosis in human.Pathophysiology of the cochlear intrastrial fluid-blood barrier (review).A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction.Sphingolipids and their metabolism in physiology and disease.Downregulation of the S1P Transporter Spinster Homology Protein 2 (Spns2) Exerts an Anti-Fibrotic and Anti-Inflammatory Effect in Human Renal Proximal Tubular Epithelial Cells.Genomic Analysis To Identify Signatures of Artificial Selection and Loci Associated with Important Economic Traits in Duroc Pigs

P2860

Q26771645-43C8C2EC-802B-4ACD-A41A-5380A32861AA Q27024207-90AB529A-DCB0-42CB-8BF9-351FB1947133 Q30386999-8991C25F-13C7-49BC-B4A9-D68475CA4B92 Q33880223-660CA524-3843-4C18-A547-3F516CE95230 Q36171317-B581A457-CB54-4B35-B608-EED5B0C1FBC2 Q36299860-607E28D0-EC9D-4F66-9708-21C4978A0B4F Q36799651-DC235713-45AE-45AE-8E1B-B4EFB4510C58 Q37072948-E4A0F6DE-88AF-4BDC-BAFE-FDB7B8550AB5 Q37208958-9355EA05-2810-4B2A-BAAC-AAD83FE256D3 Q38708802-EE8F9211-9A18-42CA-9646-9FC83AE7079C Q42375961-6711ABA0-AFEE-438D-AC52-EA1475ABB4B2 Q47374235-157BEE0F-603C-453D-A678-DB66B7660B5E Q54978854-6029A0B2-5E5F-40D8-B776-CFB828CE16E0 Q57153942-CFD0BDD0-A731-4001-83BC-3635CF102E4E

P2860

Spinster homolog 2 (spns2) deficiency causes early onset progressive hearing loss.

http://www.wikidata.org/entity/Q35377676

description

2014 nî lūn-bûn

@nan

2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

Spinster homolog 2 (spns2) deficiency causes early onset progressive hearing loss.

@ast

Spinster homolog 2 (spns2) deficiency causes early onset progressive hearing loss.

@en

type

label

Spinster homolog 2 (spns2) deficiency causes early onset progressive hearing loss.

@ast

Spinster homolog 2 (spns2) deficiency causes early onset progressive hearing loss.

@en

prefLabel

Spinster homolog 2 (spns2) deficiency causes early onset progressive hearing loss.

@ast

Spinster homolog 2 (spns2) deficiency causes early onset progressive hearing loss.

@en

P1433

Q35377676-E730628E-4925-46EE-BECE-2B5C74DC70DF

P1476

Q35377676-471EDED3-7EC2-45B7-B0CF-19CD5B3FEAE4

P2093

Q35377676-18267D9F-D6F2-4F47-BC41-DF1A39246467

Q35377676-1DA14ED1-20C8-477A-A88A-9CC54B3EB53D

Q35377676-246FB42E-E7A7-46BA-84D3-7861F1CD9517

Q35377676-5E7E744E-0264-4CA0-9B64-AAFEB259A140

Q35377676-6547B6DD-A437-4303-A89B-F11D3D279C24

Q35377676-7D2BDCF4-E44A-4C0F-80CD-D8DFC4182316

Q35377676-887EE785-6AEC-4383-8B35-5DAC90CBBBF1

Q35377676-91054296-9CC8-4409-9D58-44857524D7AC

Q35377676-B63438C9-95FA-41C9-9FEC-3C4D901561A1

Q35377676-BB372A2C-AE2B-4A9F-9E0B-52630A2042EC

P2860

Q35377676-01031481-514B-4B39-8B8C-D178B794F68B

Q35377676-035E4158-5921-4C45-9AAF-1B496747B97E

Q35377676-065916F8-AFB5-4DB5-AC18-4E0CFF388C31

Q35377676-0B6C1B93-48C2-4917-9EDD-F71564BCB922

Q35377676-133341EA-4118-45C7-9708-F741B4FDE38E

Q35377676-15FED634-C205-4871-AA44-31A5F1A3AF25

Q35377676-196AFA1C-1895-4BE1-9D84-743A22C9290A

Q35377676-1A73B0ED-25D5-49F6-9DA7-EA0E07976BE9

Q35377676-1AF2466F-887D-4A36-BAD8-68AA57E6177E

Q35377676-298D5347-88DE-4FB1-9A98-7C233103480E

P304

Q35377676-36AA0749-134A-45EA-9BF4-CD69E2167892

P31

Q35377676-D0FBFAC6-AB2F-4285-9882-0731221397F3

P356

Q35377676-F2449E57-DB50-49FA-B643-42470101A2E4

P433

Q35377676-D9519323-2D69-496B-ADCC-59212EB7F8FF

P478

Q35377676-E23BC71C-C65A-4BAC-96E2-13E02550E08E

P50

Q35377676-07BCE123-5BDF-4D76-8874-93030E0FA71C

Q35377676-F194A86F-601A-4CD6-A6CA-DCDE04411A29

P577

Q35377676-8597B983-B996-4259-A748-A30272FA45F1

P5875

Q35377676-67A17429-767A-4510-89E1-5BCB913A7F0D

P698

Q35377676-5CDE1E11-8F9C-46AD-8DDB-2725CD42B77E

P932

Q35377676-A81A5D8F-D641-43DF-A4F0-77A4A443FE31

P356

JOURNAL.PGEN.1004688

P1433

P1476

Spinster homolog 2 (spns2) deficiency causes early onset progressive hearing loss.

@en

P2093

Anastasia Nijnik

http://www.w3.org/2001/XMLSchema#string

Andrew Forge

http://www.w3.org/2001/XMLSchema#string

David Goulding

http://www.w3.org/2001/XMLSchema#string

Jacqueline K White

http://www.w3.org/2001/XMLSchema#string

Jing Chen

http://www.w3.org/2001/XMLSchema#string

Johanna Pass

http://www.w3.org/2001/XMLSchema#string

John Kelly

http://www.w3.org/2001/XMLSchema#string

Karen P Steel

http://www.w3.org/2001/XMLSchema#string

Neil Ingham

http://www.w3.org/2001/XMLSchema#string

Shalini Jadeja

http://www.w3.org/2001/XMLSchema#string

P2860

Rapid-throughput skeletal phenotyping of 100 knockout mice identifies 9 new genes that determine bone strength

A conditional knockout resource for the genome-wide study of mouse gene function

Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1-phosphate

Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes

The role of sphingosine-1-phosphate transporter Spns2 in immune system function

Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation

Sphingosine 1-phosphate promotes endothelial cell barrier integrity by Edg-dependent cytoskeletal rearrangement

The role of pericytes in blood-vessel formation and maintenance

Loss of KCNJ10 protein expression abolishes endocochlear potential and causes deafness in Pendred syndrome mouse model.

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

P304

e1004688

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1371/JOURNAL.PGEN.1004688

http://www.w3.org/2001/XMLSchema#string

P433

10

http://www.w3.org/2001/XMLSchema#string

P478

10

http://www.w3.org/2001/XMLSchema#string

P50

Daniel J Jagger

P577

2014-10-30T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

267738423

http://www.w3.org/2001/XMLSchema#string

P698

25356849

http://www.w3.org/2001/XMLSchema#string

P932

4214598

http://www.w3.org/2001/XMLSchema#string