Mitotic centromere-associated kinesin (MCAK) mediates paclitaxel resistance - Wikidata - wikimedia - TriplyDB

Mitotic centromere-associated kinesin (MCAK) mediates paclitaxel resistance

Mitotic centromere-associated kinesin (MCAK) mediates paclitaxel resistance

http://www.wikidata.org/entity/Q35379041

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Paclitaxel Through the Ages of Anticancer Therapy: Exploring Its Role in Chemoresistance and Radiation Therapy Microtubule-Binding Proteins as Promising Biomarkers of Paclitaxel Sensitivity in Cancer Chemotherapy The microtubule-binding protein Cep170 promotes the targeting of the kinesin-13 depolymerase Kif2b to the mitotic spindle.FOXM1 mediates resistance to docetaxel in gastric cancer via up-regulating Stathmin.Control of MCAK degradation and removal from centromeres Mitotic centromere-associated kinesin (MCAK): a potential cancer drug target.MiR-20a-5p represses multi-drug resistance in osteosarcoma by targeting the KIF26B gene The Elephant in the Room: The Role of Microtubules in Cancer.Molecular insight into the regulation and function of MCAK.The C-terminal region of the motor protein MCAK controls its structure and activity through a conformational switch.Peloruside A is a microtubule-stabilizing agent with exceptional anti-migratory properties in human endothelial cells Mechanisms of inhibition of endothelial cell migration by taxanes.A monomethyl auristatin E-conjugated antibody to guanylyl cyclase C is cytotoxic to target-expressing cells in vitro and in vivo.

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Mitotic centromere-associated kinesin (MCAK) mediates paclitaxel resistance

http://www.wikidata.org/entity/Q35379041

description

2011 nî lūn-bûn

@nan

2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Mitotic centromere-associated kinesin (MCAK) mediates paclitaxel resistance

@ast

Mitotic centromere-associated kinesin (MCAK) mediates paclitaxel resistance

@en

type

label

Mitotic centromere-associated kinesin (MCAK) mediates paclitaxel resistance

@ast

Mitotic centromere-associated kinesin (MCAK) mediates paclitaxel resistance

@en

prefLabel

Mitotic centromere-associated kinesin (MCAK) mediates paclitaxel resistance

@ast

Mitotic centromere-associated kinesin (MCAK) mediates paclitaxel resistance

@en

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JBC.M111.296483

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Journal of Biological Chemistry

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Mitotic centromere-associated kinesin (MCAK) mediates paclitaxel resistance

@en

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Anutosh Ganguly

http://www.w3.org/2001/XMLSchema#string

Fernando Cabral

http://www.w3.org/2001/XMLSchema#string

Hailing Yang

http://www.w3.org/2001/XMLSchema#string

Mesias Pedroza

http://www.w3.org/2001/XMLSchema#string

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Paclitaxel-dependent cell lines reveal a novel drug activity.

Inhibition of cell migration and cell division correlates with distinct effects of microtubule inhibiting drugs.

Mitotic centromere-associated kinesin is important for anaphase chromosome segregation

The spindle-assembly checkpoint in space and time

Depletion of centromeric MCAK leads to chromosome congression and segregation defects due to improper kinetochore attachments

Microtubules as a target for anticancer drugs

Dynamic instability of microtubule growth

A DNA vector-based RNAi technology to suppress gene expression in mammalian cells.

Expression of class III beta-tubulin reduces microtubule assembly and confers resistance to paclitaxel.

Mechanisms of Taxol resistance related to microtubules.

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36378-36384

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scholarly article

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10.1074/JBC.M111.296483

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P433

42

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286

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Rajat Bhattacharya

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2011-09-07T00:00:00Z

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21903575

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3196137

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