Leptin deficiency suppresses MMTV-Wnt-1 mammary tumor growth in obese mice and abrogates tumor initiating cell survival. - Wikidata - wikimedia - TriplyDB

Leptin deficiency suppresses MMTV-Wnt-1 mammary tumor growth in obese mice and abrogates tumor initiating cell survival.

Leptin deficiency suppresses MMTV-Wnt-1 mammary tumor growth in obese mice and abrogates tumor initiating cell survival.

http://www.wikidata.org/entity/Q35399575

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Adipocytes: impact on tumor growth and potential sites for therapeutic intervention Oncogenic role and therapeutic target of leptin signaling in breast cancer and cancer stem cells The integrative role of leptin, oestrogen and the insulin family in obesity-associated breast cancer: potential effects of exercise The Multifaceted Mechanism of Leptin Signaling within Tumor Microenvironment in Driving Breast Cancer Growth and Progression Deconvoluting the obesity and breast cancer link: secretome, soil and seed interactions Obesity and cancer pathogenesis.Obesity and overfeeding affecting both tumor and systemic metabolism activates the progesterone receptor to contribute to postmenopausal breast cancer Diet-induced obesity links to ER positive breast cancer progression via LPA/PKD-1-CD36 signaling-mediated microvascular remodeling.Leptin signals via TGFB1 to promote metastatic potential and stemness in breast cancer.Effects of obesity on transcriptomic changes and cancer hallmarks in estrogen receptor-positive breast cancer.Leptin and cancer: from cancer stem cells to metastasis Obesity and cancer--mechanisms underlying tumour progression and recurrence Impact of obesity on development and progression of mammary tumors in preclinical models of breast cancer Leptin induces upregulation of sphingosine kinase 1 in oestrogen receptor-negative breast cancer via Src family kinase-mediated, janus kinase 2-independent pathway Secreted human adipose leptin decreases mitochondrial respiration in HCT116 colon cancer cells.Adipocyte activation of cancer stem cell signaling in breast cancer Leptin-induced epithelial-mesenchymal transition in breast cancer cells requires β-catenin activation via Akt/GSK3- and MTA1/Wnt1 protein-dependent pathways.Inhibition of hyperglycemia-induced angiogenesis and breast cancer tumor growth by systemic injection of microRNA-467 antagonist.The Chinese medicine JC-001 enhances the chemosensitivity of Lewis lung tumors to cisplatin by modulating the immune response Leptin and Adiponectin Modulate the Self-renewal of Normal Human Breast Epithelial Stem Cells.Breast Cancer Cell Colonization of the Human Bone Marrow Adipose Tissue Niche.Leptin-STAT3-G9a Signaling Promotes Obesity-Mediated Breast Cancer Progression.Leptin regulates cyclin D1 in luminal epithelial cells of mouse MMTV-Wnt-1 mammary tumors Leptin receptor signaling is required for high-fat diet-induced atrophic gastritis in mice.Honokiol activates LKB1-miR-34a axis and antagonizes the oncogenic actions of leptin in breast cancer.Multifaceted leptin network: the molecular connection between obesity and breast cancer.Leptin as a mediator of tumor-stromal interactions promotes breast cancer stem cell activity.Obesity and Cancer: An Angiogenic and Inflammatory Link.Obesity, energy balance, and cancer: new opportunities for prevention The role of chronic inflammation in obesity-associated cancers.Genome-wide association study identifies possible genetic risk factors for colorectal adenomas.Mechanisms linking obesity and cancer Dietary energy balance modulates epithelial-to-mesenchymal transition and tumor progression in murine claudin-low and basal-like mammary tumor models.Leptin receptor maintains cancer stem-like properties in triple negative breast cancer cells.Leptin-cytokine crosstalk in breast cancer.High expression of leptin receptor leads to temozolomide resistance with exhibiting stem/progenitor cell features in gliobalastoma.Expression of p27Kip1, a cell cycle repressor protein, is inversely associated with potential carcinogenic risk in the genetic rodent models of obesity and long-lived Ames dwarf mice.The multifactorial role of leptin in driving the breast cancer microenvironment.Biochemical and molecular mechanisms for the association between obesity, chronic inflammation, and breast cancer.Leptin and adiponectin: emerging therapeutic targets in breast cancer.

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Leptin deficiency suppresses MMTV-Wnt-1 mammary tumor growth in obese mice and abrogates tumor initiating cell survival.

http://www.wikidata.org/entity/Q35399575

description

2011 nî lūn-bûn

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2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2011 թվականի հուլիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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Leptin deficiency suppresses M ...... umor initiating cell survival.

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Leptin deficiency suppresses M ...... umor initiating cell survival.

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Leptin deficiency suppresses M ...... umor initiating cell survival.

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Leptin deficiency suppresses M ...... umor initiating cell survival.

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Leptin deficiency suppresses M ...... umor initiating cell survival.

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Endocrine-related cancer

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Leptin deficiency suppresses M ...... umor initiating cell survival.

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P2093

Erinn Downs-Kelly

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Jeremy Rich

http://www.w3.org/2001/XMLSchema#string

Jinling Zhu

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Nathan A Berger

http://www.w3.org/2001/XMLSchema#string

Ofer Reizes

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Qiao Zheng

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Sarah M Dunlap

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Stephen D Hursting

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P2860

Prevalence and Trends in Obesity Among US Adults, 1999-2000

The epithelial-mesenchymal transition generates cells with properties of stem cells

Prospective identification of tumorigenic breast cancer cells

Wnt signaling in breast cancer: have we come full circle?

Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults

Basal-like breast cancer defined by five biomarkers has superior prognostic value than triple-negative phenotype

Prevalence of overweight and obesity in the United States, 1999-2004

Leptin signaling promotes the growth of mammary tumors and increases the expression of vascular endothelial growth factor (VEGF) and its receptor type two (VEGF-R2)

Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature

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