Leptin deficiency suppresses MMTV-Wnt-1 mammary tumor growth in obese mice and abrogates tumor initiating cell survival.
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Adipocytes: impact on tumor growth and potential sites for therapeutic interventionOncogenic role and therapeutic target of leptin signaling in breast cancer and cancer stem cellsThe integrative role of leptin, oestrogen and the insulin family in obesity-associated breast cancer: potential effects of exerciseThe Multifaceted Mechanism of Leptin Signaling within Tumor Microenvironment in Driving Breast Cancer Growth and ProgressionDeconvoluting the obesity and breast cancer link: secretome, soil and seed interactionsObesity and cancer pathogenesis.Obesity and overfeeding affecting both tumor and systemic metabolism activates the progesterone receptor to contribute to postmenopausal breast cancerDiet-induced obesity links to ER positive breast cancer progression via LPA/PKD-1-CD36 signaling-mediated microvascular remodeling.Leptin signals via TGFB1 to promote metastatic potential and stemness in breast cancer.Effects of obesity on transcriptomic changes and cancer hallmarks in estrogen receptor-positive breast cancer.Leptin and cancer: from cancer stem cells to metastasisObesity and cancer--mechanisms underlying tumour progression and recurrenceImpact of obesity on development and progression of mammary tumors in preclinical models of breast cancerLeptin induces upregulation of sphingosine kinase 1 in oestrogen receptor-negative breast cancer via Src family kinase-mediated, janus kinase 2-independent pathwaySecreted human adipose leptin decreases mitochondrial respiration in HCT116 colon cancer cells.Adipocyte activation of cancer stem cell signaling in breast cancerLeptin-induced epithelial-mesenchymal transition in breast cancer cells requires β-catenin activation via Akt/GSK3- and MTA1/Wnt1 protein-dependent pathways.Inhibition of hyperglycemia-induced angiogenesis and breast cancer tumor growth by systemic injection of microRNA-467 antagonist.The Chinese medicine JC-001 enhances the chemosensitivity of Lewis lung tumors to cisplatin by modulating the immune responseLeptin and Adiponectin Modulate the Self-renewal of Normal Human Breast Epithelial Stem Cells.Breast Cancer Cell Colonization of the Human Bone Marrow Adipose Tissue Niche.Leptin-STAT3-G9a Signaling Promotes Obesity-Mediated Breast Cancer Progression.Leptin regulates cyclin D1 in luminal epithelial cells of mouse MMTV-Wnt-1 mammary tumorsLeptin receptor signaling is required for high-fat diet-induced atrophic gastritis in mice.Honokiol activates LKB1-miR-34a axis and antagonizes the oncogenic actions of leptin in breast cancer.Multifaceted leptin network: the molecular connection between obesity and breast cancer.Leptin as a mediator of tumor-stromal interactions promotes breast cancer stem cell activity.Obesity and Cancer: An Angiogenic and Inflammatory Link.Obesity, energy balance, and cancer: new opportunities for preventionThe role of chronic inflammation in obesity-associated cancers.Genome-wide association study identifies possible genetic risk factors for colorectal adenomas.Mechanisms linking obesity and cancerDietary energy balance modulates epithelial-to-mesenchymal transition and tumor progression in murine claudin-low and basal-like mammary tumor models.Leptin receptor maintains cancer stem-like properties in triple negative breast cancer cells.Leptin-cytokine crosstalk in breast cancer.High expression of leptin receptor leads to temozolomide resistance with exhibiting stem/progenitor cell features in gliobalastoma.Expression of p27Kip1, a cell cycle repressor protein, is inversely associated with potential carcinogenic risk in the genetic rodent models of obesity and long-lived Ames dwarf mice.The multifactorial role of leptin in driving the breast cancer microenvironment.Biochemical and molecular mechanisms for the association between obesity, chronic inflammation, and breast cancer.Leptin and adiponectin: emerging therapeutic targets in breast cancer.
P2860
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P2860
Leptin deficiency suppresses MMTV-Wnt-1 mammary tumor growth in obese mice and abrogates tumor initiating cell survival.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Leptin deficiency suppresses M ...... umor initiating cell survival.
@ast
Leptin deficiency suppresses M ...... umor initiating cell survival.
@en
type
label
Leptin deficiency suppresses M ...... umor initiating cell survival.
@ast
Leptin deficiency suppresses M ...... umor initiating cell survival.
@en
prefLabel
Leptin deficiency suppresses M ...... umor initiating cell survival.
@ast
Leptin deficiency suppresses M ...... umor initiating cell survival.
@en
P2093
P2860
P356
P1476
Leptin deficiency suppresses M ...... umor initiating cell survival.
@en
P2093
Erinn Downs-Kelly
Jeremy Rich
Jinling Zhu
Nathan A Berger
Ofer Reizes
Qiao Zheng
Sarah M Dunlap
Stephen D Hursting
P2860
P304
P356
10.1530/ERC-11-0102
P577
2011-07-11T00:00:00Z