Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature - Wikidata - wikimedia - TriplyDB

Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature

Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature

http://www.wikidata.org/entity/Q29622952

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Metastasis is an early event in mouse mammary carcinomas and is associated with cells bearing stem cell markers Non-small cell lung cancer cells expressing CD44 are enriched for stem cell-like properties Distinct expression levels and patterns of stem cell marker, aldehyde dehydrogenase isoform 1 (ALDH1), in human epithelial cancers MUC1-C oncoprotein activates ERK→C/EBPβ signaling and induction of aldehyde dehydrogenase 1A1 in breast cancer cells Double-negative feedback loop between reprogramming factor LIN28 and microRNA let-7 regulates aldehyde dehydrogenase 1-positive cancer stem cells CD133: to be or not to be, is this the real question?c-Jun induces mammary epithelial cellular invasion and breast cancer stem cell expansion.CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts Tumor-endothelial interaction links the CD44(+)/CD24(-) phenotype with poor prognosis in early-stage breast cancer Thresholds for therapies: highlights of the St Gallen International Expert Consensus on the primary therapy of early breast cancer 2009 Management of relapsed ovarian cancer: a review Anti-Cancer Stem-like Cell Compounds in Clinical Development - An Overview and Critical Appraisal The IL-8/IL-8R Axis: A Double Agent in Tumor Immune Resistance Oncogenic role of leptin and Notch interleukin-1 leptin crosstalk outcome in cancer Roles for miRNAs in endocrine resistance in breast cancer A review on hepatocyte nuclear factor-1beta and tumor Aldehyde dehydrogenase as a marker and functional mediator of metastasis in solid tumors Steroid hormones, steroid receptors, and breast cancer stem cells Tumor-Derived Cell Lines as Molecular Models of Cancer Pharmacogenomics In vivo molecular imaging of cancer stem cells Tumor heterogeneity and its implication for drug delivery Emerging role of cancer stem cells in the biology and treatment of ovarian cancer: basic knowledge and therapeutic possibilities for an innovative approach Identifying and targeting tumor-initiating cells in the treatment of breast cancer Pancreatic cancer stem cells: emerging target for designing novel therapy Targeting CSC-related miRNAs for cancer therapy by natural agents Metastatic mechanisms in follicular cell-derived thyroid cancer Genomic profiling in triple-negative breast cancer Wound healing and cancer stem cells: inflammation as a driver of treatment resistance in breast cancer Inflammatory breast cancer: New factors contribute to disease etiology: A review High efficiency integration of three-dimensional functional microdevices inside a microfluidic chip by using femtosecond laser multifoci parallel microfabrication The Notch pathway is important in maintaining the cancer stem cell population in pancreatic cancer Trastuzumab-resistant cells rely on a HER2-PI3K-FoxO-survivin axis and are sensitive to PI3K inhibitors Mammary gland stem cells and their application in breast cancer In vitro models of cancer stem cells and clinical applications Targeted Cancer Therapy: Vital Oncogenes and a New Molecular Genetic Paradigm for Cancer Initiation Progression and Treatment ABCB5 maintains melanoma-initiating cells through a proinflammatory cytokine signaling circuit A perspective on cancer cell metastasis ErbB2 and p38γ MAPK mediate alcohol-induced increase in breast cancer stem cells and metastasis The impact of low-dose carcinogens and environmental disruptors on tissue invasion and metastasis Doxorubicin in combination with a small TGFbeta inhibitor: a potential novel therapy for metastatic breast cancer in mouse models

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P2860

Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature

http://www.wikidata.org/entity/Q29622952

description

2009 nî lūn-bûn

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2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2009 թվականի փետրվարին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

Breast cancer cell lines conta ...... a distinct molecular signature

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Breast cancer cell lines conta ...... a distinct molecular signature

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Breast cancer cell lines conta ...... a distinct molecular signature

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0008-5472.CAN-08-2741

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Cancer Research

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Breast cancer cell lines conta ...... a distinct molecular signature

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Florence Monville

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François Bertucci

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Gabriela Dontu

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Giorgio Stassi

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Julie Dutcher

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Julien Wicinski

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Luc Xerri

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Mark E Diebel

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Marty Brown

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Max S Wicha

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P2860

The Hallmarks of Cancer

Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer

Cluster analysis and display of genome-wide expression patterns

A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome

IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland

Inhibition of aldehyde dehydrogenase and retinoid signaling induces the expansion of human hematopoietic stem cells

Prospective identification of tumorigenic breast cancer cells

Identification and expansion of human colon-cancer-initiating cells

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

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1302-1313

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scholarly article

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87758

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10.1158/0008-5472.CAN-08-2741

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4

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Christophe Ginestier

Emmanuelle Charafe-Jauffret

Daniel Birnbaum

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2009-02-03T00:00:00Z

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23974613

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19190339

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