Kinetochore motors drive congression of peripheral polar chromosomes by overcoming random arm-ejection forces.
about
Thirty years of search and capture: The complex simplicity of mitotic spindle assemblyRole of the Number of Microtubules in Chromosome Segregation during Cell DivisionPolar Ejection Forces Promote the Conversion from Lateral to End-on Kinetochore-Microtubule Attachments on Mono-oriented ChromosomesA Novel Time-Dependent CENP-E Inhibitor with Potent Antitumor ActivitySUMOylated NKAP is essential for chromosome alignment by anchoring CENP-E to kinetochoresAurora A Kinase Amplifies a Midzone Phosphorylation Gradient to Promote High-Fidelity Cytokinesis.Aneuploidy generates proteotoxic stress and DNA damage concurrently with p53-mediated post-mitotic apoptosis in SAC-impaired cellsMitosis. Microtubule detyrosination guides chromosomes during mitosisThe chromokinesin Klp3a and microtubules facilitate acentric chromosome segregation.Mechanisms of Chromosome Congression during Mitosis.The Elephant in the Room: The Role of Microtubules in Cancer.The spindle assembly checkpoint promotes chromosome bi-orientation: A novel Mad1 role in chromosome alignment.Molecular mechanism of dynein recruitment to kinetochores by the Rod-Zw10-Zwilch complex and Spindly.Late mitotic functions of Aurora kinases.Centrosome age regulates kinetochore-microtubule stability and biases chromosome mis-segregationDynein prevents erroneous kinetochore-microtubule attachments in mitosis.Mad1 promotes chromosome congression by anchoring a kinesin motor to the kinetochore.Aurora A Kinase Contributes to a Pole-Based Error Correction Pathway.Microtubule Sliding within the Bridging Fiber Pushes Kinetochore Fibers Apart to Segregate Chromosomes.Cracking the (tubulin) code of mitosis.Congressing kinetochores progressively load Ska complexes to prevent force-dependent detachment.Diverse mitotic functions of the cytoskeletal cross-linking protein Shortstop suggest a role in Dynein/Dynactin activity.A Regulatory Switch Alters Chromosome Motions at the Metaphase-to-Anaphase Transition.Biophysics of Microtubule End Coupling at the Kinetochore.GTSE1 regulates spindle microtubule dynamics to control Aurora B kinase and Kif4A chromokinesin on chromosome arms.Optogenetic control of kinetochore function.Lateral attachment of kinetochores to microtubules is enriched in prometaphase rosette and facilitates chromosome alignment and bi-orientation establishment.Antagonism between the dynein and Ndc80 complexes at kinetochores controls the stability of kinetochore-microtubule attachments during mitosis.Chromosome Segregation Is Biased by Kinetochore Size.CLIP-170 tethers kinetochores to microtubule plus ends against poleward force by dynein for stable kinetochore-microtubule attachment.Kinetochore regulation: Let there be light.Complete microtubule-kinetochore occupancy favours the segregation of merotelic attachments.F-Actin nucleated on chromosomes coordinates their capture by microtubules in oocyte meiosis
P2860
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P2860
Kinetochore motors drive congression of peripheral polar chromosomes by overcoming random arm-ejection forces.
description
2014 nî lūn-bûn
@nan
2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Kinetochore motors drive congr ...... ng random arm-ejection forces.
@ast
Kinetochore motors drive congr ...... ng random arm-ejection forces.
@en
type
label
Kinetochore motors drive congr ...... ng random arm-ejection forces.
@ast
Kinetochore motors drive congr ...... ng random arm-ejection forces.
@en
prefLabel
Kinetochore motors drive congr ...... ng random arm-ejection forces.
@ast
Kinetochore motors drive congr ...... ng random arm-ejection forces.
@en
P2860
P50
P356
P1433
P1476
Kinetochore motors drive congr ...... ing random arm-ejection forces
@en
P2093
Stephan Geley
P2860
P2888
P304
P356
10.1038/NCB3060
P577
2014-11-10T00:00:00Z