Voluntary ethanol intake predicts κ-opioid receptor supersensitivity and regionally distinct dopaminergic adaptations in macaques
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Downregulation of the endogenous opioid peptides in the dorsal striatum of human alcoholicsChronic ethanol self-administration in macaques shifts dopamine feedback inhibition to predominantly D2 receptors in nucleus accumbens coreStress-Induced Enhancement of Ethanol Intake in C57BL/6J Mice with a History of Chronic Ethanol Exposure: Involvement of Kappa Opioid Receptors.Translational Research on Habit and AlcoholIncreased presynaptic regulation of dopamine neurotransmission in the nucleus accumbens core following chronic ethanol self-administration in female macaquesSupersensitive Kappa Opioid Receptors Promotes Ethanol Withdrawal-Related Behaviors and Reduce Dopamine Signaling in the Nucleus Accumbens.Distinct Effects of Nalmefene on Dopamine Uptake Rates and Kappa Opioid Receptor Activity in the Nucleus Accumbens Following Chronic Intermittent Ethanol Exposure.Identifying Future Drinkers: Behavioral Analysis of Monkeys Initiating Drinking to Intoxication is Predictive of Future Drinking Classification.Studies using macaque monkeys to address excessive alcohol drinking and stress interactions.Alcohol and basal ganglia circuitry: Animal models.Role of the Dynorphin/Kappa Opioid Receptor System in the Motivational Effects of Ethanol.Dopamine synthesis in alcohol drinking-prone and -resistant mouse strains.Synaptic adaptations to chronic ethanol intake in male rhesus monkey dorsal striatum depend on age of drinking onset.Chronic ethanol exposure increases inhibition of optically targeted phasic dopamine release in the nucleus accumbens core and medial shell ex vivo.Presynaptic Ethanol Actions: Potential Roles in Ethanol Seeking.Preclinical evaluation of the kappa-opioid receptor antagonist CERC-501 as a candidate therapeutic for alcohol use disorders.Genome-wide analysis of the nucleus accumbens identifies DNA methylation signals differentiating low/binge from heavy alcohol drinking.
P2860
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P2860
Voluntary ethanol intake predicts κ-opioid receptor supersensitivity and regionally distinct dopaminergic adaptations in macaques
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2015 nî lūn-bûn
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2015 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2015 թվականի ապրիլին հրատարակված գիտական հոդված
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2015年の論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年论文
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name
Voluntary ethanol intake predi ...... nergic adaptations in macaques
@ast
Voluntary ethanol intake predi ...... nergic adaptations in macaques
@en
type
label
Voluntary ethanol intake predi ...... nergic adaptations in macaques
@ast
Voluntary ethanol intake predi ...... nergic adaptations in macaques
@en
prefLabel
Voluntary ethanol intake predi ...... nergic adaptations in macaques
@ast
Voluntary ethanol intake predi ...... nergic adaptations in macaques
@en
P2093
P2860
P50
P1476
Voluntary ethanol intake predi ...... nergic adaptations in macaques
@en
P2093
Christa M Helms
David M Lovinger
Erin S Calipari
Verginia C Cuzon Carlson
P2860
P304
P356
10.1523/JNEUROSCI.4820-14.2015
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P577
2015-04-01T00:00:00Z