Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia. - Wikidata - wikimedia - TriplyDB

Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia.

Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia.

http://www.wikidata.org/entity/Q35486110

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Tumour Cell Heterogeneity Personalized Cancer Risk Assessments for Space Radiation Exposures Molecular landscape of acute myeloid leukemia in younger adults and its clinical relevance The influence of subclonal resistance mutations on targeted cancer therapy Therapy-Related Myeloid Neoplasms Evolutionary determinants of cancer How cell death shapes cancer TP53 mutation in patients with high-risk acute myeloid leukaemia treated with allogeneic haematopoietic stem cell transplantation.Evolved Cellular Mechanisms to Respond to Genotoxic Insults: Implications for Radiation-Induced Hematologic Malignancies Identification of Circulating Tumor DNA for the Early Detection of Small-cell Lung Cancer Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes Ultra-deep sequencing detects ovarian cancer cells in peritoneal fluid and reveals somatic TP53 mutations in noncancerous tissues Targeting acute myeloid leukemia with TP53-independent vosaroxin.Phase I study of the aurora A kinase inhibitor alisertib with induction chemotherapy in patients with acute myeloid leukemia.PIGN gene expression aberration is associated with genomic instability and leukemic progression in acute myeloid leukemia with myelodysplastic features.The genetics of myelodysplastic syndrome: from clonal haematopoiesis to secondary leukaemia Interactions and relevance of blast percentage and treatment strategy among younger and older patients with acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS)Individualizing Therapeutic Strategies in Acute Myeloid Leukemia: Moving Beyond the 'One-Size-Fits-All' Approach.Clonal haematopoiesis harbouring AML-associated mutations is ubiquitous in healthy adults Clonal Hematopoiesis Associated With Adverse Outcomes After Autologous Stem-Cell Transplantation for Lymphoma.TP53 mutation characteristics in therapy-related myelodysplastic syndromes and acute myeloid leukemia is similar to de novo diseases.Evidence that synthetic lethality underlies the mutual exclusivity of oncogenic KRAS and EGFR mutations in lung adenocarcinoma.Optimizing cancer genome sequencing and analysis.Clinical evaluation of panel testing by next-generation sequencing (NGS) for gene mutations in myeloid neoplasms.TP53 mutations in de novo acute myeloid leukemia patients: longitudinal follow-ups show the mutation is stable during disease evolution.Leveraging protein quaternary structure to identify oncogenic driver mutations.An ultra-deep sequencing strategy to detect sub-clonal TP53 mutations in presentation chronic lymphocytic leukaemia cases using multiple polymerases.Genomic Copy Number Variations in the Myelodysplastic Syndrome and Acute Myeloid Leukemia Patients with del(5q) and/or -7/del(7q).Alkylator-Induced and Patient-Derived Xenograft Mouse Models of Therapy-Related Myeloid Neoplasms Model Clinical Disease and Suggest the Presence of Multiple Cell Subpopulations with Leukemia Stem Cell Activity Acute DNA damage activates the tumour suppressor p53 to promote radiation-induced lymphoma The CCL2/CCR2 Axis Affects Transmigration and Proliferation but Not Resistance to Chemotherapy of Acute Myeloid Leukemia Cells.Translocation (6;15)(q12;q15): A Novel Mutation in a Patient with Therapy-Related Myelodysplastic Syndrome.Rapid expansion of preexisting nonleukemic hematopoietic clones frequently follows induction therapy for de novo AML.Regain control of p53: Targeting leukemia stem cells by isoform-specific HDAC inhibition Somatic Mosaic Mutations in PPM1D and TP53 in the Blood of Women With Ovarian Carcinoma.Hydroxyurea synergizes with valproic acid in wild-type p53 acute myeloid leukaemia.Hematologic Recovery after Pretransplant Chemotherapy Does Not Influence Survival after Allogeneic Hematopoietic Cell Transplantation in Acute Myeloid Leukemia Patients.Effect of therapy-related acute myeloid leukemia on the outcome of patients with acute myeloid leukemia.Development and validation of a comprehensive genomic diagnostic tool for myeloid malignancies.Genetic hierarchy and temporal variegation in the clonal history of acute myeloid leukaemia.

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Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia.

http://www.wikidata.org/entity/Q35486110

description

2014 nî lūn-bûn

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2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencing

Recurring mutations found by sequencing an acute myeloid leukemia genome

Fast and accurate short read alignment with Burrows-Wheeler transform

Another fork in the road--life or death decisions by the tumour suppressor p53

Fast gapped-read alignment with Bowtie 2

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

The Sequence Alignment/Map format and SAMtools

The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments

High-throughput droplet digital PCR system for absolute quantitation of DNA copy number

Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration

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