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An iron regulatory gene signature predicts outcome in breast cancer.

An iron regulatory gene signature predicts outcome in breast cancer.

http://www.wikidata.org/entity/Q35501239

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Increasing Superoxide Production and the Labile Iron Pool in Tumor Cells may Sensitize Them to Extracellular Ascorbate Evidence for the Influence of the Iron Regulatory MHC Class I Molecule HFE on Tumor Progression in Experimental Models and Clinical Populations Hemochromatosis enhances tumor progression via upregulation of intracellular iron in head and neck cancer.Iron and cancer: more ore to be mined.Targeting iron metabolism in drug discovery and delivery Prediction of adjuvant chemotherapy response in triple negative breast cancer with discovery and targeted proteomics.DEAD-box helicase DP103 defines metastatic potential of human breast cancers.Elevation in inflammatory serum biomarkers predicts response to trastuzumab-containing therapy.Classifying ten types of major cancers based on reverse phase protein array profiles.A systems biology approach to iron metabolism.Intracellular Iron Chelation Modulates the Macrophage Iron Phenotype with Consequences on Tumor Progression.Aberrations in the Iron Regulatory Gene Signature Are Associated with Decreased Survival in Diffuse Infiltrating Gliomas.Activated Oncogenic Pathway Modifies Iron Network in Breast Epithelial Cells: A Dynamic Modeling Perspective.Knowledge building insights on biomarkers of arsenic toxicity to keratinocytes and melanocytes Candidate early detection protein biomarkers for ER+/PR+ invasive ductal breast carcinoma identified using pre-clinical plasma from the WHI observational study.Iron-targeting antitumor activity of gallium compounds and novel insights into triapine(®)-metal complexes.Iron chelators with topoisomerase-inhibitory activity and their anticancer applications.Local iron homeostasis in the breast ductal carcinoma microenvironment.Regulators of Iron Homeostasis: New Players in Metabolism, Cell Death, and Disease.ABCB6 mRNA and DNA methylation levels serve as useful biomarkers for prediction of early intrahepatic recurrence of hepatitis C virus-related hepatocellular carcinoma.Cellular iron metabolism in prognosis and therapy of breast cancer.Decreased ferroportin promotes myeloma cell growth and osteoclast differentiation A Validated Prognostic Multigene Expression Assay for Overall Survival in Resected Colorectal Cancer Liver Metastases A reactivity-based probe of the intracellular labile ferrous iron pool.The regulation of SOX7 and its tumor suppressive role in breast cancer.A Novel Tumor-Activated Prodrug Strategy Targeting Ferrous Iron Is Effective in Multiple Preclinical Cancer Models Effects of Anti-repulsive Guidance Molecule C (RGMc/Hemojuvelin) Antibody on Hepcidin and Iron in Mouse Liver and Tumor Xenografts DCYTB is a predictor of outcome in breast cancer that functions via iron-independent mechanisms.Tumor-initiating cells of breast and prostate origin show alterations in the expression of genes related to iron metabolism.Genome-wide screen identifies a novel prognostic signature for breast cancer survival.IRP2 regulates breast tumor growth.The STEAP protein family: versatile oxidoreductases and targets for cancer immunotherapy with overlapping and distinct cellular functions.Shotgun proteomics of archival triple-negative breast cancer samples.Regulation of iron homeostasis by the p53-ISCU pathway.An important role of the hepcidin-ferroportin signaling in affecting tumor growth and metastasis.Myeloid zinc-finger 1 (MZF-1) suppresses prostate tumor growth through enforcing ferroportin-conducted iron egress.Intracellular reduction/activation of a disulfide switch in thiosemicarbazone iron chelators Mitochondria and Iron: current questions.Iron overload and altered iron metabolism in ovarian cancer.The iron chelators Dp44mT and DFO inhibit TGF-β-induced epithelial-mesenchymal transition via up-regulation of N-Myc downstream-regulated gene 1 (NDRG1).

P2860

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P2860

An iron regulatory gene signature predicts outcome in breast cancer.

http://www.wikidata.org/entity/Q35501239

description

2011 nî lūn-bûn

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2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի օգոստոսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

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2011年論文

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2011年论文

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name

An iron regulatory gene signature predicts outcome in breast cancer.

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An iron regulatory gene signature predicts outcome in breast cancer.

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type

label

An iron regulatory gene signature predicts outcome in breast cancer.

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An iron regulatory gene signature predicts outcome in breast cancer.

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prefLabel

An iron regulatory gene signature predicts outcome in breast cancer.

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An iron regulatory gene signature predicts outcome in breast cancer.

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Cancer Research

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An iron regulatory gene signature predicts outcome in breast cancer

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Frank M Torti

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Jeff W Chou

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Jonas Bergh

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Ralph D'Agostino

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Suzy V Torti

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P2860

The hereditary hemochromatosis protein, HFE, specifically regulates transferrin-mediated iron uptake in HeLa cells

Gene ontology: tool for the unification of biology

The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding

Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

Semi-supervised methods to predict patient survival from gene expression data

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

Summaries of Affymetrix GeneChip probe level data

Repeated observation of breast tumor subtypes in independent gene expression data sets

Ferroportin and iron regulation in breast cancer progression and prognosis

Supervised risk predictor of breast cancer based on intrinsic subtypes

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