Activation of a 66-kilodalton human endothelial cell matrix metalloprotease by Streptococcus pyogenes extracellular cysteine protease.
about
Crystal structure of the zymogen form of the group A Streptococcus virulence factor SpeB: An integrin-binding cysteine proteasePathogenesis of group A streptococcal infectionsIdentification of Rgg-regulated exoproteins of Streptococcus pyogenes.IdeS, a novel streptococcal cysteine proteinase with unique specificity for immunoglobulin G.EndoS from Streptococcus pyogenes is hydrolyzed by the cysteine proteinase SpeB and requires glutamic acid 235 and tryptophans for IgG glycan-hydrolyzing activitySpeB of Streptococcus pyogenes differentially modulates antibacterial and receptor activating properties of human chemokines.Absence of a cysteine protease effect on bacterial virulence in two murine models of human invasive group A streptococcal infection.Decreased necrotizing fasciitis capacity caused by a single nucleotide mutation that alters a multiple gene virulence axisGenetic inactivation of an extracellular cysteine protease (SpeB) expressed by Streptococcus pyogenes decreases resistance to phagocytosis and dissemination to organsEffect of group A streptococcal cysteine protease on invasion of epithelial cells.Opsonic antibodies to the surface M protein of group A streptococci in pooled normal immunoglobulins (IVIG): potential impact on the clinical efficacy of IVIG therapy for severe invasive group A streptococcal infections.Role of streptococcal pyrogenic exotoxin B in the mouse model of group A streptococcal infection.A role for trigger factor and an rgg-like regulator in the transcription, secretion and processing of the cysteine proteinase of Streptococcus pyogenes.The complete genome sequence of Mycoplasma bovis strain Hubei-1Streptococcal pyrogenic exotoxin B induces apoptosis and reduces phagocytic activity in U937 cells.The rgg gene of Streptococcus pyogenes NZ131 positively influences extracellular SPE B production.Fibrinogen cleavage by the Streptococcus pyogenes extracellular cysteine protease and generation of antibodies that inhibit enzyme proteolytic activity.Absence of SpeB production in virulent large capsular forms of group A streptococcal strain 64Streptococcal erythrogenic toxin B abrogates fibronectin-dependent internalization of Streptococcus pyogenes by cultured mammalian cellsReplacement of histidine 340 with alanine inactivates the group A Streptococcus extracellular cysteine protease virulence factorInverse relation between disease severity and expression of the streptococcal cysteine protease, SpeB, among clonal M1T1 isolates recovered from invasive group A streptococcal infection casesA natural variant of the cysteine protease virulence factor of group A Streptococcus with an arginine-glycine-aspartic acid (RGD) motif preferentially binds human integrins alphavbeta3 and alphaIIbbeta3.Determining antibody-binding site of streptococcal pyrogenic exotoxin B to protect mice from group a streptococcus infectionStreptococcus pyogenes c-di-AMP phosphodiesterase, GdpP, influences SpeB processing and virulenceApplication of the C3-binding motif of streptococcal pyrogenic exotoxin B to protect mice from invasive group a streptococcal infectionPlasminogen binding by group A streptococcal isolates from a region of hyperendemicity for streptococcal skin infection and a high incidence of invasive infection.Degradation of complement 3 by streptococcal pyrogenic exotoxin B inhibits complement activation and neutrophil opsonophagocytosis.Inactivation of Streptococcus pyogenes extracellular cysteine protease significantly decreases mouse lethality of serotype M3 and M49 strains.emm1/sequence type 28 strains of group A streptococci that express covR at early stationary phase are associated with increased growth and earlier SpeB secretion.Molecular analysis of the role of the group A streptococcal cysteine protease, hyaluronic acid capsule, and M protein in a murine model of human invasive soft-tissue infection.Extracellular cysteine protease produced by Streptococcus pyogenes participates in the pathogenesis of invasive skin infection and dissemination in mice.Regulation of matrix metalloproteinase expression in endothelial cells by heat-inactivated Streptococcus pneumoniaeExpression and characterization of group A Streptococcus extracellular cysteine protease recombinant mutant proteins and documentation of seroconversion during human invasive disease episodesCysteine protease activity and histamine release from the human mast cell line HMC-1 stimulated by recombinant streptococcal pyrogenic exotoxin B/streptococcal cysteine protease.Contribution of CsrR-regulated virulence factors to the progress and outcome of murine skin infections by Streptococcus pyogenes.The majority of 9,729 group A streptococcus strains causing disease secrete SpeB cysteine protease: pathogenesis implications.Proapoptotic effect of proteolytic activation of matrix metalloproteinases by Streptococcus pyogenes thiol proteinase (Streptococcus pyrogenic exotoxin B)The streptococcal cysteine protease SpeB is not a natural immunoglobulin-cleaving enzyme.
P2860
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P2860
Activation of a 66-kilodalton human endothelial cell matrix metalloprotease by Streptococcus pyogenes extracellular cysteine protease.
description
1996 nî lūn-bûn
@nan
1996 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Activation of a 66-kilodalton ...... tracellular cysteine protease.
@ast
Activation of a 66-kilodalton ...... tracellular cysteine protease.
@en
type
label
Activation of a 66-kilodalton ...... tracellular cysteine protease.
@ast
Activation of a 66-kilodalton ...... tracellular cysteine protease.
@en
prefLabel
Activation of a 66-kilodalton ...... tracellular cysteine protease.
@ast
Activation of a 66-kilodalton ...... tracellular cysteine protease.
@en
P2093
P2860
P1476
Activation of a 66-kilodalton ...... tracellular cysteine protease.
@en
P2093
A M Marciel
J M Musser
P2860
P304
P407
P577
1996-11-01T00:00:00Z