Toward predicting drug-induced liver injury: parallel computational approaches to identify multidrug resistance protein 4 and bile salt export pump inhibitors.
about
Rho-kinase/myosin light chain kinase pathway plays a key role in the impairment of bile canaliculi dynamics induced by cholestatic drugs.Drug-induced liver injury: Do we know everything?Hepatic drug transporters: the journey so far.Recent advances in the exploration of the bile salt export pump (BSEP/ABCB11) function.The Promise of New Technologies to Reduce, Refine, or Replace Animal Use while Reducing Risks of Drug Induced Liver Injury in Pharmaceutical Development.The pathogenesis of drug-induced liver injury.Identification of novel MRP3 inhibitors based on computational models and validation using an in vitro membrane vesicle assay.Renal Drug Transporters and Drug Interactions.The in silico identification of human bile salt export pump (ABCB11) inhibitors associated with cholestatic drug-induced liver injury.Role of Hepatic Drug Transporters in Drug Development.Can BSEP Inhibition Testing In Drug Discovery And Development Reduce Liver Injury Risk? - An International Transporter Consortium Perspective
P2860
Q27320565-88706A69-FE65-4062-BA1E-458DBD515FC8Q37748005-7F59ECEA-9F3D-4152-8F42-D35BA7B5FDA9Q38560889-5D97F9D7-07BE-4E60-B6DF-3ACD0EBB137DQ38634838-6B83501F-0E3F-41D6-B875-1BE9E225BF9CQ38774776-A8CF7547-1BD8-4886-9C74-A3E8502E0AADQ38849978-BBFCBE6E-F725-4FE1-8B74-9B78E1181673Q38941229-0622B6A7-E112-4EEF-9F99-437BFFBC5544Q39140289-A89D15E2-2D20-4257-AD95-BDE8E754EDEDQ48349259-AFB7AA20-9EC5-4995-88B0-772AAA1E28D0Q51659233-298B7506-6F3E-42CA-B610-113267533E62Q57111135-5598C953-8E21-460A-9747-EFB96D256D67
P2860
Toward predicting drug-induced liver injury: parallel computational approaches to identify multidrug resistance protein 4 and bile salt export pump inhibitors.
description
2015 nî lūn-bûn
@nan
2015 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի մարտին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Toward predicting drug-induced ...... e salt export pump inhibitors.
@ast
Toward predicting drug-induced ...... e salt export pump inhibitors.
@en
type
label
Toward predicting drug-induced ...... e salt export pump inhibitors.
@ast
Toward predicting drug-induced ...... e salt export pump inhibitors.
@en
prefLabel
Toward predicting drug-induced ...... e salt export pump inhibitors.
@ast
Toward predicting drug-induced ...... e salt export pump inhibitors.
@en
P2093
P2860
P356
P1476
Toward predicting drug-induced ...... e salt export pump inhibitors.
@en
P2093
Kathleen Köck
Matthew A Welch
Peter W Swaan
Thomas J Urban
P2860
P304
P356
10.1124/DMD.114.062539
P50
P577
2015-03-03T00:00:00Z