Decitabine priming enhances the antileukemic effects of exportin 1 (XPO1) selective inhibitor selinexor in acute myeloid leukemia

Decitabine priming enhances the antileukemic effects of exportin 1 (XPO1) selective inhibitor selinexor in acute myeloid leukemia

Item
http://www.wikidata.org/entity/Q35533613
Targeting the Nuclear Export Protein XPO1/CRM1 Reverses Epithelial to Mesenchymal TransitionNext-generation XPO1 inhibitor shows improved efficacy and in vivo tolerability in hematological malignanciesEpigenetics: A primer for clinicians.A phase 1 clinical trial of single-agent selinexor in acute myeloid leukemia.XPO1 in B cell hematological malignancies: from recurrent somatic mutations to targeted therapy.Treatment of Relapsed/Refractory Acute Myeloid Leukemia.XPO1 Inhibition using Selinexor Synergizes with Chemotherapy in Acute Myeloid Leukemia by Targeting DNA Repair and Restoring Topoisomerase IIα to the Nucleus.KPT-8602, a second-generation inhibitor of XPO1-mediated nuclear export, is well tolerated and highly active against AML blasts and leukemia-initiating cells.Phase I Study of Selinexor, a Selective Inhibitor of Nuclear Export, in Combination With Fludarabine and Cytarabine, in Pediatric Relapsed or Refractory Acute Leukemia.Selinexor (KPT-330) demonstrates anti-tumor efficacy in preclinical models of triple-negative breast cancer.Decitabine-Induced Changes in Human Myelodysplastic Syndrome Cell Line SKM-1 Are Mediated by FOXO3A Activation.Clinical Dosing Regimen of Selinexor Maintains Normal Immune Homeostasis and T-cell Effector Function in Mice: Implications for Combination with Immunotherapy.
P2860

Decitabine priming enhances the antileukemic effects of exportin 1 (XPO1) selective inhibitor selinexor in acute myeloid leukemia

Item
http://www.wikidata.org/entity/Q35533613
description
2015 nî lūn-bûn
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2015 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2015年の論文
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2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Decitabine priming enhances th ...... exor in acute myeloid leukemia
@ast
Decitabine priming enhances th ...... exor in acute myeloid leukemia
@en
type
label
Decitabine priming enhances th ...... exor in acute myeloid leukemia
@ast
Decitabine priming enhances th ...... exor in acute myeloid leukemia
@en
prefLabel
Decitabine priming enhances th ...... exor in acute myeloid leukemia
@ast
Decitabine priming enhances th ...... exor in acute myeloid leukemia
@en
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Decitabine priming enhances th ...... exor in acute myeloid leukemia
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P2093
P2860
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10.1182/BLOOD-2014-10-607648
P407
P433
P478
P50
P577
P5875
P698
P921
P932