Enhanced virulence, airway inflammation and impaired lung function induced by respiratory syncytial virus deficient in secreted G protein
about
Human metapneumovirus glycoprotein G inhibits innate immune responsesThe cysteine-rich region and secreted form of the attachment G glycoprotein of respiratory syncytial virus enhance the cytotoxic T-lymphocyte response despite lacking major histocompatibility complex class I-restricted epitopes.Animal models of human respiratory syncytial virus diseaseThe secreted form of respiratory syncytial virus G glycoprotein helps the virus evade antibody-mediated restriction of replication by acting as an antigen decoy and through effects on Fc receptor-bearing leukocytes.A chimeric A2 strain of respiratory syncytial virus (RSV) with the fusion protein of RSV strain line 19 exhibits enhanced viral load, mucus, and airway dysfunctionLong-term activation of TLR3 by poly(I:C) induces inflammation and impairs lung function in miceA highly attenuated recombinant human respiratory syncytial virus lacking the G protein induces long-lasting protection in cotton rats.Barometric whole body plethysmography in mice.
P2860
Q21090523-DAF568B1-8DCD-40F7-8C3F-68E027FBCBABQ34651258-01F8F96D-9439-4FA3-8A68-F6E4D6485E8CQ35159747-77A5EBD0-3A35-4962-86CA-BFC38C978DE1Q36994686-9910F767-8A32-49EE-AFA4-D747414C9864Q37157161-FB1236C8-5BC4-4945-A490-26C1444EE85CQ37222041-581E8A06-2A43-4604-8913-3668059B7842Q39696619-99A8A195-F40E-4BC8-81A7-FE8D6576910FQ47814644-A1C39DCB-7754-4567-AB9D-B2DE6B4844A3
P2860
Enhanced virulence, airway inflammation and impaired lung function induced by respiratory syncytial virus deficient in secreted G protein
description
2004 nî lūn-bûn
@nan
2004 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Enhanced virulence, airway inf ...... eficient in secreted G protein
@ast
Enhanced virulence, airway inf ...... eficient in secreted G protein
@en
type
label
Enhanced virulence, airway inf ...... eficient in secreted G protein
@ast
Enhanced virulence, airway inf ...... eficient in secreted G protein
@en
prefLabel
Enhanced virulence, airway inf ...... eficient in secreted G protein
@ast
Enhanced virulence, airway inf ...... eficient in secreted G protein
@en
P2860
P356
P1433
P1476
Enhanced virulence, airway inf ...... eficient in secreted G protein
@en
P2093
P2860
P304
P356
10.1136/THX.2003.017343
P407
P577
2004-06-01T00:00:00Z