Continuum of prion protein structures enciphers a multitude of prion isolate-specified phenotypes.
about
Darwinian evolution of prions in cell cultureMechanisms of protein seeding in neurodegenerative diseasesPrion-like properties of Tau protein: the importance of extracellular Tau as a therapeutic targetThe strain-encoded relationship between PrP replication, stability and processing in neurons is predictive of the incubation period of diseaseThe physical relationship between infectivity and prion protein aggregates is strain-dependentEvidence that bank vole PrP is a universal acceptor for prionsMolecular mechanisms for protein-encoded inheritanceDe novo generation of prion strainsBiochemical properties of highly neuroinvasive prion strainsRelationships between PrPSc stability and incubation time for United States scrapie isolates in a natural host systemProgress towards structural understanding of infectious sheep PrP-amyloid.Conformational stability of PrP amyloid fibrils controls their smallest possible fragment size.Prion formation, but not clearance, is supported by protein misfolding cyclic amplification.Resistance of bovine spongiform encephalopathy (BSE) prions to inactivationInoculation of scrapie with the self-assembling RADA-peptide disrupts prion accumulation and extends hamster survival.Biochemical characterization of prion strains in bank volesInvestigating the conformational stability of prion strains through a kinetic replication model.Protease-sensitive synthetic prions.Biology and genetics of prions causing neurodegenerationA new method for the characterization of strain-specific conformational stability of protease-sensitive and protease-resistant PrPSc.Contribution of specific residues of the β-solenoid fold to HET-s prion function, amyloid structure and stability.Prion dynamics and the quest for the genetic determinant in protein-only inheritanceGene expression profiling of brains from bovine spongiform encephalopathy (BSE)-infected cynomolgus macaques.Chemical induction of misfolded prion protein conformers in cell culture.Dynamic reorganization of metabolic enzymes into intracellular bodiesCoinfecting prion strains compete for a limiting cellular resource.Prion strain mutation determined by prion protein conformational compatibility and primary structure.Protease-sensitive conformers in broad spectrum of distinct PrPSc structures in sporadic Creutzfeldt-Jakob disease are indicator of progression rate.PrP(Sc)-specific antibodies do not induce prion disease or misfolding of PrP(C) in highly susceptible Tga20 mice.Spontaneous generation of mammalian prionsPrions: En route from structural models to structures.Human prion strain selection in transgenic mice.Amyloid structure: conformational diversity and consequences.De novo prions.Distinct stability states of disease-associated human prion protein identified by conformation-dependent immunoassayPropagation of RML prions in mice expressing PrP devoid of GPI anchor leads to formation of a novel, stable prion strainSmall protease sensitive oligomers of PrPSc in distinct human prions determine conversion rate of PrP(C).The prion hypothesis: from biological anomaly to basic regulatory mechanism.Prions.Transfer of a prion strain to different hosts leads to emergence of strain variants.
P2860
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P2860
Continuum of prion protein structures enciphers a multitude of prion isolate-specified phenotypes.
description
2006 nî lūn-bûn
@nan
2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Continuum of prion protein str ...... isolate-specified phenotypes.
@ast
Continuum of prion protein str ...... isolate-specified phenotypes.
@en
type
label
Continuum of prion protein str ...... isolate-specified phenotypes.
@ast
Continuum of prion protein str ...... isolate-specified phenotypes.
@en
prefLabel
Continuum of prion protein str ...... isolate-specified phenotypes.
@ast
Continuum of prion protein str ...... isolate-specified phenotypes.
@en
P2860
P50
P356
P1476
Continuum of prion protein str ...... isolate-specified phenotypes.
@en
P2093
David Peretz
Hoang-Oanh B Nguyen
P2860
P304
19105-19110
P356
10.1073/PNAS.0608970103
P407
P577
2006-12-01T00:00:00Z