Functional annotation of native enhancers with a Cas9-histone demethylase fusion. - Wikidata - wikimedia - TriplyDB

Functional annotation of native enhancers with a Cas9-histone demethylase fusion.

Functional annotation of native enhancers with a Cas9-histone demethylase fusion.

http://www.wikidata.org/entity/Q35554363

about

Next generation sequencing technology and genomewide data analysis: Perspectives for retinal research Brain tumor modeling using the CRISPR/Cas9 system: state of the art and view to the future Therapeutic opportunities in Ewing sarcoma: EWS-FLI inhibition via LSD1 targeting Making sense of GWAS: using epigenomics and genome engineering to understand the functional relevance of SNPs in non-coding regions of the human genome Beyond editing: repurposing CRISPR-Cas9 for precision genome regulation and interrogation Applications of CRISPR-Cas systems in neuroscience How specific is CRISPR/Cas9 really?Epigenetic marks: regulators of livestock phenotypes and conceivable sources of missing variation in livestock improvement programs Applications of Engineered DNA-Binding Molecules Such as TAL Proteins and the CRISPR/Cas System in Biology Research Enabling functional genomics with genome engineering Strategies for precision modulation of gene expression by epigenome editing: an overview Genomic Views of Transcriptional Enhancers: Essential Determinants of Cellular Identity and Activity-Dependent Responses in the CNS Chromatin Dynamics in Lineage Commitment and Cellular Reprogramming The CRISPR revolution and its impact on cancer research The epigenome: the next substrate for engineering CRISPR-Mediated Epigenome Editing Epigenetic Editing: On the Verge of Reprogramming Gene Expression at Will Ligand-binding domains of nuclear receptors facilitate tight control of split CRISPR activity Stabilization of Foxp3 expression by CRISPR-dCas9-based epigenome editing in mouse primary T cells.Genome engineering of stem cell organoids for disease modeling.Complex transcriptional modulation with orthogonal and inducible dCas9 regulators.Genetic and epigenetic control of gene expression by CRISPR-Cas systems.Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers.Diverse evolutionary roots and mechanistic variations of the CRISPR-Cas systems.Applications of CRISPR technologies in research and beyond.Systematic Analysis of Known and Candidate Lysine Demethylases in the Regulation of Myoblast Differentiation.LSD1: biologic roles and therapeutic targeting.Epigenetic Control of Stem Cell Potential during Homeostasis, Aging, and Disease Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.Crystal Structure of Cpf1 in Complex with Guide RNA and Target DNA Genome-scale CRISPR pooled screens.Directed evolution using dCas9-targeted somatic hypermutation in mammalian cells.CORALINA: a universal method for the generation of gRNA libraries for CRISPR-based screening Functional interrogation of non-coding DNA through CRISPR genome editing.CRISPR-Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome.Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements CRISPR/dCas9-mediated Transcriptional Inhibition Ameliorates the Epigenetic Dysregulation at D4Z4 and Represses DUX4-fl in FSH Muscular Dystrophy.Cas9 Variants Expand the Target Repertoire in Caenorhabditis elegans Towards a compendium of essential genes - From model organisms to synthetic lethality in cancer cells.

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P2860

Functional annotation of native enhancers with a Cas9-histone demethylase fusion.

http://www.wikidata.org/entity/Q35554363

description

2015 nî lūn-bûn

@nan

2015年の論文

@ja

2015年論文

@yue

2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

@zh-mo

2015年論文

@zh-tw

2015年论文

@wuu

2015年论文

@zh

2015年论文

@zh-cn

name

Functional annotation of native enhancers with a Cas9-histone demethylase fusion.

@ast

Functional annotation of native enhancers with a Cas9-histone demethylase fusion.

@en

type

label

Functional annotation of native enhancers with a Cas9-histone demethylase fusion.

@ast

Functional annotation of native enhancers with a Cas9-histone demethylase fusion.

@en

prefLabel

Functional annotation of native enhancers with a Cas9-histone demethylase fusion.

@ast

Functional annotation of native enhancers with a Cas9-histone demethylase fusion.

@en

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Functional annotation of native enhancers with a Cas9-histone demethylase fusion

@en

P2093

Barbara Tabak

http://www.w3.org/2001/XMLSchema#string

Hannah Pham

http://www.w3.org/2001/XMLSchema#string

Manuel Garber

http://www.w3.org/2001/XMLSchema#string

René Maehr

http://www.w3.org/2001/XMLSchema#string

Ryan M Genga

http://www.w3.org/2001/XMLSchema#string

P2860

RNA-guided human genome engineering via Cas9

CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes

RNA-guided editing of bacterial genomes using CRISPR-Cas systems

NCBI reference sequences (RefSeq): a curated non-redundant sequence database of genomes, transcripts and proteins

KRAB-zinc finger proteins and KAP1 can mediate long-range transcriptional repression through heterochromatin spreading

Optical control of mammalian endogenous transcription and epigenetic states

Dissecting self-renewal in stem cells with RNA interference

Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells

Super-enhancers in the control of cell identity and disease

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

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401-403

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scholarly article

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10.1038/NMETH.3325

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5

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12

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Noah J Silverstein

Nicola A Kearns

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2015-03-16T00:00:00Z

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273637870

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25775043

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4414811

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