about
BRCA1 is a negative modulator of the PRC2 complexBreastfeeding and the risk of breast cancer in BRCA1 and BRCA2 mutation carriersBasal cytokeratins and their relationship to the cellular origin and functional classification of breast cancerPathology and gene expression of hereditary breast tumors associated with BRCA1, BRCA2 and CHEK2 gene mutationsGenomic evidence for rod monochromacy in sloths and armadillos suggests early subterranean history for XenarthraExpression of Nestin associates with BRCA1 mutations, a basal-like phenotype and aggressive breast cancer.BRCA1-mutated and basal-like breast cancers have similar aCGH profiles and a high incidence of protein truncating TP53 mutations.The alpha- and beta-subunits of the human UDP-N-acetylglucosamine:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase [corrected] are encoded by a single cDNA.Expression of aldehyde dehydrogenase 1 (ALDH1) is associated with basal-like markers and features of aggressive tumours in African breast cancer.Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer.Systems biology and genomics of breast cancer.Genetic predisposition directs breast cancer phenotype by dictating progenitor cell fate.Wnt/catenin signaling in adult stem cell physiology and disease.Structural and functional implication of RAP80 ΔGlu81 mutation.CK8/18 expression, the basal phenotype, and family history in identifying BRCA1-associated breast cancer in the Ontario site of the breast cancer family registryExpression of the epigenetic factor BORIS (CTCFL) in the human genomeA model for breast cancer risk based on stem-cell theory.Basal breast cancer: a complex and deadly molecular subtypeAdvances in breast cancer: pathways to personalized medicineExpression of Stem Cell Markers in Preinvasive Tubal Lesions of Ovarian Carcinoma.BRCA1 regulates human mammary stem/progenitor cell fate.Positive selection in the evolution of cancer.The origin of breast tumor heterogeneity.A review of the ethnic differences in breast cancer.Identification and characterization of cancer initiating cells from BRCA1 related mammary tumors using markers for normal mammary stem cells.BRCA1 Protein Expression Level and CD44(+)Phenotype in Breast Cancer Patients.BRCA1-hapoinsufficiency: Unraveling the molecular and cellular basis for tissue-specific cancerReduced BRCA1 transcript levels in freshly isolated blood leukocytes from BRCA1 mutation carriers is mutation specificImplications of the cancer stem-cell hypothesis for breast cancer prevention and therapy.Keeping abreast of the mammary epithelial hierarchy and breast tumorigenesis.Dysregulation of the BRCA1/long non-coding RNA NEAT1 signaling axis contributes to breast tumorigenesis.p16INK4a suppresses BRCA1-deficient mammary tumorigenesis.Triple-negative breast cancer: present challenges and new perspectives.Targeting tumour-initiating cells to improve the cure rates for triple-negative breast cancer.The cell of origin of BRCA1 mutation-associated breast cancer: a cautionary tale of gene expression profiling.BRCA1--conductor of the breast stem cell orchestra: the role of BRCA1 in mammary gland development and identification of cell of origin of BRCA1 mutant breast cancer.Mouse models of BRCA1 and their application to breast cancer research.Rad51c- and Trp53-double-mutant mouse model reveals common features of homologous recombination-deficient breast cancers.Selection for EGFR gene amplification in a breast epithelial cell line with basal-like phenotype and hereditary background.BRCA1 plays a role in the hypoxic response by regulating HIF-1alpha stability and by modulating vascular endothelial growth factor expression.
P2860
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P2860
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
BRCA1 functions as a breast stem cell regulator.
@ast
BRCA1 functions as a breast stem cell regulator.
@en
type
label
BRCA1 functions as a breast stem cell regulator.
@ast
BRCA1 functions as a breast stem cell regulator.
@en
prefLabel
BRCA1 functions as a breast stem cell regulator.
@ast
BRCA1 functions as a breast stem cell regulator.
@en
P2860
P356
P1476
BRCA1 functions as a breast stem cell regulator.
@en
P2860
P356
10.1136/JMG.2003.013805
P407
P577
2004-01-01T00:00:00Z