BRCA1 regulates human mammary stem/progenitor cell fate.
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The CD44+/CD24- phenotype is enriched in basal-like breast tumorsALDH1A1 maintains ovarian cancer stem cell-like properties by altered regulation of cell cycle checkpoint and DNA repair network signalingAn efficient weighted graph strategy to identify differentiation associated genes in embryonic stem cellsA NIK-IKKα module expands ErbB2-induced tumor-initiating cells by stimulating nuclear export of p27/Kip1BRCA1 is a negative modulator of the PRC2 complexMechanisms of bone metastases of breast cancerDouble-negative feedback loop between reprogramming factor LIN28 and microRNA let-7 regulates aldehyde dehydrogenase 1-positive cancer stem cellsFragile histidine triad protein, WW domain-containing oxidoreductase protein Wwox, and activator protein 2gamma expression levels correlate with basal phenotype in breast cancerP-cadherin and the journey to cancer metastasisERrrr…where are the progenitors? Hormone receptors and mammary cell heterogeneityBRCA1 and estrogen/estrogen receptor in breast cancer: where they interact?Epithelial-mesenchymal plasticity of breast cancer stem cells: implications for metastasis and therapeutic resistanceMammary gland stem cells: more puzzles than explanationsSLUG: Critical regulator of epithelial cell identity in breast development and cancerA novel BRCA1 mutation in a patient with breast and ovarian cancer: A case report.RANKL/RANK: from bone loss to the prevention of breast cancerMultiple lineages of human breast cancer stem/progenitor cells identified by profiling with stem cell markersPhenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancerBreast cancer classification and prognostication through diverse systems along with recent emerging findings in this respect; the dawn of new perspectives in the clinical applications.A role for the TGFbeta-Par6 polarity pathway in breast cancer progressionFrequently increased epidermal growth factor receptor (EGFR) copy numbers and decreased BRCA1 mRNA expression in Japanese triple-negative breast cancersLympho-vascular invasion in BRCA related breast cancer compared to sporadic controls.Molecular Signaling of Progesterone, Growth Hormone, Wnt, and HER in Mammary Glands of Dogs, Rodents, and Humans: New Treatment Target Identification.Cadmium malignantly transforms normal human breast epithelial cells into a basal-like phenotypeAltered gene expression in morphologically normal epithelial cells from heterozygous carriers of BRCA1 or BRCA2 mutationsFrom normal cell types to malignant phenotypes.Risk of second breast cancers after lobular carcinoma in situ according to hormone receptor statusPrevalence of the variant allele rs61764370 T>G in the 3'UTR of KRAS among Dutch BRCA1, BRCA2 and non-BRCA1/BRCA2 breast cancer families.Redefining the expression and function of the inhibitor of differentiation 1 in mammary gland developmentTumorigenic WAP-T mouse mammary carcinoma cells: a model for a self-reproducing homeostatic cancer cell system.Cross-species comparison of aCGH data from mouse and human BRCA1- and BRCA2-mutated breast cancersEpithelial-stromal interaction 1 (EPSTI1) substitutes for peritumoral fibroblasts in the tumor microenvironmentTip30 controls differentiation of murine mammary luminal progenitor to estrogen receptor-positive luminal cell through regulating FoxA1 expressionMammary development and breast cancer: the role of stem cellsPhenotypic and functional characterisation of the luminal cell hierarchy of the mammary gland.Prevalence and predictors of loss of wild type BRCA1 in estrogen receptor positive and negative BRCA1-associated breast cancersBRCA1 haploinsufficiency leads to altered expression of genes involved in cellular proliferation and development.Morphological and immunohistochemical study of ovarian and tubal dysplasia associated with tamoxifenEffects of childhood body size on breast cancer tumour characteristicsAldehyde dehydrogenase and estrogen receptor define a hierarchy of cellular differentiation in the normal human mammary epithelium.
P2860
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P2860
BRCA1 regulates human mammary stem/progenitor cell fate.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
BRCA1 regulates human mammary stem/progenitor cell fate.
@ast
BRCA1 regulates human mammary stem/progenitor cell fate.
@en
type
label
BRCA1 regulates human mammary stem/progenitor cell fate.
@ast
BRCA1 regulates human mammary stem/progenitor cell fate.
@en
prefLabel
BRCA1 regulates human mammary stem/progenitor cell fate.
@ast
BRCA1 regulates human mammary stem/progenitor cell fate.
@en
P2093
P2860
P356
P1476
BRCA1 regulates human mammary stem/progenitor cell fate.
@en
P2093
Celina G Kleer
Christophe Ginestier
Gabriela Dontu
Hailey Foco
Max S Wicha
Sofia D Merajver
Suling Liu
P2860
P304
P356
10.1073/PNAS.0711613105
P407
P577
2008-01-29T00:00:00Z