RBM7 subunit of the NEXT complex binds U-rich sequences and targets 3'-end extended forms of snRNAs
about
Cajal bodies and snRNPs - friends with benefits.Altered RNA metabolism due to a homozygous RBM7 mutation in a patient with spinal motor neuropathy.Structure of the RBM7-ZCCHC8 core of the NEXT complex reveals connections to splicing factors.An Mtr4/ZFC3H1 complex facilitates turnover of unstable nuclear RNAs to prevent their cytoplasmic transport and global translational repression.Structural basis for mutually exclusive co-transcriptional nuclear cap-binding complexes with either NELF-E or ARS2.The RNA exosome and RNA exosome-linked disease.Exosome cofactor hMTR4 competes with export adaptor ALYREF to ensure balanced nuclear RNA pools for degradation and export.Targeting the nuclear RNA exosome: Poly(A) binding proteins enter the stage.RNA surveillance by the nuclear RNA exosome: mechanisms and significance.Variants in EXOSC9 Disrupt the RNA Exosome and Result in Cerebellar Atrophy with Spinal Motor Neuronopathy.RRM domain of human RBM7: purification, crystallization and structure determination.Structural analysis of human ARS2 as a platform for co-transcriptional RNA sorting.The RNA Exosome Adaptor ZFC3H1 Functionally Competes with Nuclear Export Activity to Retain Target Transcripts.Structural basis for MTR4-ZCCHC8 interactions that stimulate the MTR4 helicase in the nuclear exosome-targeting complex.Surveillance-ready transcription: nuclear RNA decay as a default fate.
P2860
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P2860
RBM7 subunit of the NEXT complex binds U-rich sequences and targets 3'-end extended forms of snRNAs
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
RBM7 subunit of the NEXT compl ...... '-end extended forms of snRNAs
@ast
RBM7 subunit of the NEXT compl ...... '-end extended forms of snRNAs
@en
type
label
RBM7 subunit of the NEXT compl ...... '-end extended forms of snRNAs
@ast
RBM7 subunit of the NEXT compl ...... '-end extended forms of snRNAs
@en
prefLabel
RBM7 subunit of the NEXT compl ...... '-end extended forms of snRNAs
@ast
RBM7 subunit of the NEXT compl ...... '-end extended forms of snRNAs
@en
P2093
P2860
P356
P1476
RBM7 subunit of the NEXT compl ...... '-end extended forms of snRNAs
@en
P2093
David Potesil
Dominika Hrossova
Josef Pasulka
Richard Stefl
Tomas Sikorsky
Zbynek Zdrahal
P2860
P304
P356
10.1093/NAR/GKV240
P407
P577
2015-04-07T00:00:00Z