about
PTH receptor-1 signalling-mechanistic insights and therapeutic prospectsARF6 Is an Actionable Node that Orchestrates Oncogenic GNAQ Signaling in Uveal MelanomaRedefining the concept of protease-activated receptors: cathepsin S evokes itch via activation of MrgprsA Pluridimensional View of Biased Agonism.The Hedgehog pathway effector smoothened exhibits signaling competency in the absence of ciliary accumulation.International Union of Basic and Clinical Pharmacology. XCIII. The parathyroid hormone receptors--family B G protein-coupled receptors.Optimizing optogenetic constructs for control over signaling and cell behaviours.The MMP-1/PAR-1 Axis Enhances Proliferation and Neuronal Differentiation of Adult Hippocampal Neural Progenitor CellsThe role of kinetic context in apparent biased agonism at GPCRs.Sorting nexin 27 couples PTHR trafficking to retromer for signal regulation in osteoblasts during bone growth.Studying the regulation of endosomal cAMP production in GPCR signaling.Actin-Sorting Nexin 27 (SNX27)-Retromer Complex Mediates Rapid Parathyroid Hormone Receptor Recycling.Different cAMP sources are critically involved in G protein-coupled receptor CRHR1 signaling.Minireview: Role of intracellular scaffolding proteins in the regulation of endocrine G protein-coupled receptor signaling.The ins and outs of adrenergic signaling.Spatio-Temporal Parameters of Endosomal Signaling in Cancer: Implications for New Treatment Options.Phosphodiesterase-4 inhibition as a therapeutic strategy for metabolic disorders.G Protein-Coupled Receptor Signaling Through β-Arrestin-Dependent Mechanisms.Barcoding of GPCR trafficking and signaling through the various trafficking roadmaps by compartmentalized signaling networks.The Diverse Roles of Arrestin Scaffolds in G Protein-Coupled Receptor Signaling.Endocrinology and the brain: corticotropin-releasing hormone signaling.Activated G Protein Gαs Samples Multiple Endomembrane Compartments.Visualization of ligand-induced dopamine D2S and D2L receptor internalization by TIRF microscopyInternalized TSH receptors en route to the TGN induce local Gs-protein signaling and gene transcriptionPharmacodynamic Actions of a Long-Acting PTH Analog (LA-PTH) in Thyroparathyroidectomized (TPTX) Rats and Normal Monkeys.A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling.Backbone Modification of a Parathyroid Hormone Receptor-1 Antagonist/Inverse AgonistGαs regulates Glucagon-Like Peptide 1 Receptor-mediated cyclic AMP generation at Rab5 endosomal compartment.Differential phosphorylation signals control endocytosis of GPR15Functional PDF Signaling in the Drosophila Circadian Neural Circuit Is Gated by Ral A-Dependent Modulation.Design and validation of the first cell-impermeant melatonin receptor agonist.Src family kinase inhibitors blunt the PACAP-induced PAC1 receptor endocytosis, phosphorylation of ERK and increase in cardiac neuron excitability.Recruitment of endosomal signaling mediates the forskolin modulation of guinea pig cardiac neuron excitability.Genetic evidence that β-arrestins are dispensable for the initiation of β2-adrenergic receptor signaling to ERK.Development of Potent, Protease-Resistant Agonists of the Parathyroid Hormone Receptor with Broad β Residue Distribution.Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release.A kinetic view of GPCR allostery and biased agonism.GPCR signalling from within the cell.Site-specific polyubiquitination differentially regulates parathyroid hormone receptor-initiated MAPK signaling and cell proliferation.Quantitative Single-Cell Analysis of Signaling Pathways Activated Immediately Downstream of Histamine Receptor Subtypes.
P2860
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P2860
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Endosomal generation of cAMP in GPCR signaling.
@ast
Endosomal generation of cAMP in GPCR signaling.
@en
type
label
Endosomal generation of cAMP in GPCR signaling.
@ast
Endosomal generation of cAMP in GPCR signaling.
@en
prefLabel
Endosomal generation of cAMP in GPCR signaling.
@ast
Endosomal generation of cAMP in GPCR signaling.
@en
P2860
P356
P1476
Endosomal generation of cAMP in GPCR signaling.
@en
P2093
Thomas J Gardella
P2860
P2888
P304
P356
10.1038/NCHEMBIO.1611
P577
2014-09-01T00:00:00Z
P5875
P6179
1023337429