about
The multifunctional protein GC1q-R interacts specifically with the i3 loop arginine cluster of the vasopressin V2 receptor.Endosomal GPCR signaling turned off by negative feedback actions of PKA and v-ATPaseEndosomal generation of cAMP in GPCR signaling.The Polycystin-1, Lipoxygenase, and α-Toxin Domain Regulates Polycystin-1 Trafficking.Actin-Sorting Nexin 27 (SNX27)-Retromer Complex Mediates Rapid Parathyroid Hormone Receptor Recycling.Spatially restricted G protein-coupled receptor activity via divergent endocytic compartments.Past, present and future of vasopressin and oxytocin receptor oligomers, prototypical GPCR models to study dimerization processes.β2-adrenergic receptor control of endosomal PTH receptor signaling via Gβγ.Regulation of GPCR signal networks via membrane trafficking.Cdc42 activation couples fluid shear stress to apical endocytosis in proximal tubule cells.Arachidonic acid-dependent gene regulation during preadipocyte differentiation controls adipocyte potential.Design and validation of the first cell-impermeant melatonin receptor agonist.Integration of GPCR Signaling and Sorting from Very Early Endosomes via Opposing APPL1 Mechanisms.Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release.Biased Signaling and Allosteric Modulation at the FSHRDesign and synthesis of cyclic and linear peptide-agarose tools for baiting interacting protein partners of GPCRsGq/11-dependent regulation of endosomal cAMP generation by parathyroid hormone class B GPCRParathyroid hormone initiates dynamic NHERF1 phosphorylation cycling and conformational changes that regulate NPT2A-dependent phosphate transportCa2+ allostery in PTH-receptor signalingStructure and dynamics of the active human parathyroid hormone receptor-1Use of Backbone Modification To Enlarge the Spatiotemporal Diversity of Parathyroid Hormone Receptor-1 Signaling via Biased Agonism
P50
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P50
description
investigador
@es
researcher
@en
wetenschapper
@nl
name
Frédéric Jean-Alphonse
@en
Frédéric Jean-Alphonse
@nl
type
label
Frédéric Jean-Alphonse
@en
Frédéric Jean-Alphonse
@nl
prefLabel
Frédéric Jean-Alphonse
@en
Frédéric Jean-Alphonse
@nl
P31
P496
0000-0002-7380-5825