A novel mRNA of the A4 amyloid precursor gene coding for a possibly secreted protein.
about
Lysosomal processing of amyloid precursor protein to A beta peptides: a distinct role for cathepsin SCTCF is essential for up-regulating expression from the amyloid precursor protein promoter during differentiation of primary hippocampal neuronsIdentification of a mouse brain cDNA that encodes a protein related to the Alzheimer disease-associated amyloid beta protein precursorExpression of the amyloid precursor protein gene in mouse oocytes and embryos.Genetic dissection of Alzheimer disease, a heterogeneous disorder.Alternative polyadenylation of the amyloid protein precursor mRNA regulates translationGenetics of Alzheimer diseaseThe expression of the amyloid precursor protein (APP) is regulated by two GC-elements in the promoter.Normal processing of the Alzheimer's disease amyloid beta protein precursor generates potentially amyloidogenic carboxyl-terminal derivatives.Linkage and mutational analysis of familial Alzheimer disease kindreds for the APP gene region.Homology of the amyloid beta protein precursor in monkey and human supports a primate model for beta amyloidosis in Alzheimer's disease.Amino acid sequence RERMS represents the active domain of amyloid beta/A4 protein precursor that promotes fibroblast growth.Study of the synthesis and secretion of normal and artificial mutants of murine amyloid precursor protein (APP): cleavage of APP occurs in a late compartment of the default secretion pathway.Amyloid precursor protein (APP) and beta A4 amyloid in the etiology of Alzheimer's disease: precursor-product relationships in the derangement of neuronal function.Processing of the Alzheimer's disease beta A4 amyloid protein precursor (APP).Alzheimer's disease from the perspective of the systemic and localized forms of amyloidosis.Aged non-human primates: an animal model of age-associated neurodegenerative disease.Expression of the human beta-amyloid precursor protein gene from a yeast artificial chromosome in transgenic mice.Mechanisms of amyloid deposition in Alzheimer's disease.Expression of active secreted forms of human amyloid beta-protein precursor by recombinant baculovirus-infected insect cells.Altered levels of amyloid protein precursor transcripts in the basal forebrain of behaviorally impaired aged rats.Image analysis microspectroscopy shows that neurons participate in the genesis of a subset of early primitive (diffuse) senile plaques.Inhibition of trypsin by the beta-amyloid protein precursor. A comparative study between transfected cells, human brain and cerebrospinal fluid.A beta amyloidogenesis: unique, or variation on a systemic theme?Retinoic acid induced differentiated neuroblastoma cells show increased expression of the beta A4 amyloid gene of Alzheimer's disease and an altered splicing pattern.Epitope map of two polyclonal antibodies that recognize amyloid lesions in patients with Alzheimer's disease.Immunohistochemical colocalization of amyloid precursor protein with cerebrovascular amyloid of Alzheimer's disease.The cytoplasmic domain of Alzheimer's amyloid precursor protein is phosphorylated at Thr654, Ser655, and Thr668 in adult rat brain and cultured cells.Ultrastructural localization of the putative precursors of the A4 amyloid protein associated with Alzheimer's disease.Beta/A4 proteinlike immunoreactive granular structures in the brain of senescence-accelerated mouseA basic amino acid in the cytoplasmic domain of Alzheimer's beta-amyloid precursor protein (APP) is essential for cleavage of APP at the alpha-site.Studies of amyloid beta-protein precursor expression in Alzheimer's disease.Does the Kunitz domain from the Alzheimer's amyloid beta protein precursor inhibit a kallikrein responsible for post-translational processing of nerve growth factor precursor?Ultrastructural and biochemical basis of Alzheimer's disease
P2860
Q24528220-57F8B3E0-81D0-4A1C-99D0-35F2E03F07D8Q28580883-3ACE04A3-ADAC-471B-AC04-B45CCE37F7C6Q28588379-C9424B3D-A250-4627-8A14-34E81F6A6DF2Q33383984-6FA2D5F3-3B06-4857-919C-1038D375FD53Q33909158-83BF2789-CAB3-4924-92D3-89A7434B0BFBQ33938228-E9978393-B67E-43A1-AD8B-1074791FE260Q34604101-4372B455-0795-4A8A-BD73-AF218A9B7FD8Q35010710-4EC026D6-477A-4C5A-8B5F-6716CA66A7E7Q35186129-CE995174-C787-4535-9AB5-D5ACFAB245C2Q35196153-F00337F9-752B-4FF4-8A44-B3511BF514C6Q35831302-A3E0F3E4-87DC-4A87-A09A-13486339E2ADQ36233243-90279F47-0C01-4C59-AD83-10D84E6F226BQ36383137-E96B9098-4D1C-4502-BEA7-E7F5BE19CFA4Q36476991-46FBC310-A126-4852-AF0B-E41BAB65A15EQ36477006-6CBDD84A-E20E-4F92-85E9-AD3FC2087E4BQ36477010-DDD9DDD1-14DB-46ED-BBA4-92624A416400Q36554296-4A64472E-BCFB-448B-9EAC-C70B03A11567Q36661391-A58F3B2A-5F18-4300-BC1C-0D43DC17FCEBQ36927540-945E403A-93C8-4B5B-848E-0A4B1ADB9141Q37624305-9B5337F5-4EB5-4BC8-BA5C-EC0A72E95BF1Q37739715-F5C15750-D788-4802-9A6A-0C701C919C1EQ41139875-1FEFF761-12D7-46C6-B587-53A138A5BEF1Q41640423-F73A5E78-1DC8-4946-82F7-81AD2F727BF6Q41651595-60D0B226-B2A3-4918-B2C9-25AF71068364Q41722059-3436F0E7-F385-4946-B487-F0CAE87AE4E6Q41841963-40F2321C-93B5-422F-A34C-276194AB5A3AQ41915861-3F7B3063-5147-4B9B-88C3-604C2E4A0C06Q41941163-8D835CEE-40FC-4DAD-8553-626543826164Q41966247-DA716A55-F7AF-4172-954A-9375AA8B931FQ42050208-E3657A9D-9A4D-44E5-BC12-7AB0E837867BQ47827840-647913A9-793F-4530-B8EA-8677B329F391Q53181973-AA072136-701C-4CAF-9859-486FDC49F7BFQ54711066-FD82F90E-6114-4A99-96A8-07ACCFC9E5A7Q58216336-2B29BAC4-0EBA-491B-833B-895528C9A971
P2860
A novel mRNA of the A4 amyloid precursor gene coding for a possibly secreted protein.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
A novel mRNA of the A4 amyloid precursor gene coding for a possibly secreted protein.
@ast
A novel mRNA of the A4 amyloid precursor gene coding for a possibly secreted protein.
@en
type
label
A novel mRNA of the A4 amyloid precursor gene coding for a possibly secreted protein.
@ast
A novel mRNA of the A4 amyloid precursor gene coding for a possibly secreted protein.
@en
prefLabel
A novel mRNA of the A4 amyloid precursor gene coding for a possibly secreted protein.
@ast
A novel mRNA of the A4 amyloid precursor gene coding for a possibly secreted protein.
@en
P356
P1433
P1476
A novel mRNA of the A4 amyloid precursor gene coding for a possibly secreted protein.
@en
P2093
de Sauvage F
P304
P356
10.1126/SCIENCE.2569763
P407
P577
1989-08-01T00:00:00Z