Detection of hypermethylation of the p16(INK4A) gene promoter in chronic hepatitis and cirrhosis associated with hepatitis B or C virus - Wikidata - wikimedia - TriplyDB

Detection of hypermethylation of the p16(INK4A) gene promoter in chronic hepatitis and cirrhosis associated with hepatitis B or C virus

Detection of hypermethylation of the p16(INK4A) gene promoter in chronic hepatitis and cirrhosis associated with hepatitis B or C virus

http://www.wikidata.org/entity/Q35565676

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Promoter methylation of MLH1, PMS2, MSH2 and p16 is a phenomenon of advanced-stage HCCs Detection of aberrant p16INK4A methylation in sera of patients with liver cirrhosis and hepatocellular carcinoma Molecular mechanisms of gender disparity in hepatitis B virus-associated hepatocellular carcinoma DNA methylation changes in normal liver tissues and hepatocellular carcinoma with different viral infection.Promoter methylation of CDKN2A and lack of p16 expression characterize patients with hepatocellular carcinoma.Alteration of DNA methylation in gastrointestinal carcinogenesis.Quantitative evaluation of RASSF1A methylation in the non-lesional, regenerative and neoplastic liver.P16 gene hypermethylation and hepatocellular carcinoma: a systematic review and meta-analysis.INK4a-ARF alterations in liver cell adenoma DNA methylation similarities in genes of black South Africans with systemic lupus erythematosus and systemic sclerosis.Eradication of Helicobacter pylori infection reverses E-cadherin promoter hypermethylation.DNA markers in molecular diagnostics for hepatocellular carcinoma.Aberrant CpG island hypermethylation along multistep hepatocarcinogenesis.Evaluation of INK4A promoter methylation using pyrosequencing and circulating cell-free DNA from patients with hepatocellular carcinoma.Association of low p16INK4a and p15INK4b mRNAs expression with their CpG islands methylation with human hepatocellular carcinogenesis SOCS1 is a suppressor of liver fibrosis and hepatitis-induced carcinogenesis CpG methylation of MGMT and hMLH1 promoter in hepatocellular carcinoma associated with hepatitis viral infection.DNA methylation profiling identifies novel markers of progression in hepatitis B-related chronic liver disease.Molecular mechanism underlying the functional loss of cyclindependent kinase inhibitors p16 and p27 in hepatocellular carcinoma DNA methylation in hepatocellular carcinoma.Aberrant p16INK4A methylation: Relation to viral related chronic liver disease and hepatocellular carcinoma.Clinical implications of DNA methylation in hepatocellular carcinoma.Regulatory mechanisms of tumor suppressor P16(INK4A) and their relevance to cancer.Potential usefulness of DNA methylation as a risk marker for digestive cancer associated with inflammation.Clinical significance of cell cycle inhibitors in hepatocellular carcinoma.The Complex Relationship between Liver Cancer and the Cell Cycle: A Story of Multiple Regulations.Epigenetic mechanisms regulating the development of hepatocellular carcinoma and their promise for therapeutics.Virus-host interplay in hepatitis B virus infection and epigenetic treatment strategies.Genome-wide analysis of DNA methylation identifies novel cancer-related genes in hepatocellular carcinoma.Restitution of gene expression and histone acetylation signatures altered by hepatitis B virus through antiviral microRNA-like molecules in nontransformed murine hepatocytes.Aberrant CpG island hypermethylation and down-regulation of Oct-6 mRNA expression in human hepatocellular carcinoma.Association of glypican-3 expression with growth signaling molecules in hepatocellular carcinoma.Risk prediction of gastric cancer by analysis of aberrant DNA methylation in non-neoplastic gastric epithelium.Methylation status of p14ARF, p15INK4b, and p16INK4a genes in human hepatocellular carcinoma.p16 Methylation was associated with the development, age, hepatic viruses infection of hepatocellular carcinoma, and p16 expression had a poor survival: A systematic meta-analysis (PRISMA).Gene methylation in non-neoplastic mucosa of gastric cancer: age or Helicobacter pylori related?Association of p16INK4A hypermethylation with hepatitis B virus X protein expression in the early stage of HBV-associated hepatocarcinogenesis.Carcinogenetic risk estimation based on quantification of DNA methylation levels in liver tissue at the precancerous stage.Quantitative methylation analysis reveals gender and age differences in p16INK4a hypermethylation in hepatitis B virus-related hepatocellular carcinoma.INK4a-ARF alterations in liver cell adenoma.

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P2860

Detection of hypermethylation of the p16(INK4A) gene promoter in chronic hepatitis and cirrhosis associated with hepatitis B or C virus

http://www.wikidata.org/entity/Q35565676

description

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Detection of hypermethylation ...... ed with hepatitis B or C virus

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Detection of hypermethylation ...... ed with hepatitis B or C virus

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Endo T

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Imai K

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Itoh F

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Kaneto H

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Karino Y

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Ohmura T

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Omata M

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P2860

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

Hepatitis C virus core from two different genotypes has an oncogenic potential but is not sufficient for transforming primary rat embryo fibroblasts in cooperation with the H-ras oncogene.

Hepatitis C virus core protein cooperates with ras and transforms primary rat embryo fibroblasts to tumorigenic phenotype

Overexpression of cyclin D1 enhances gene amplification

Infection with human immunodeficiency virus type 1 upregulates DNA methyltransferase, resulting in de novo methylation of the gamma interferon (IFN-gamma) promoter and subsequent downregulation of IFN-gamma production.

Inactivation of p16 in human mammary epithelial cells by CpG island methylation

Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3

Hepatocellular carcinoma: recent progress.

Aberrant methylation of p16(INK4a) is an early event in lung cancer and a potential biomarker for early diagnosis

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372-377

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scholarly article

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10.1136/GUT.48.3.372

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3

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11171828

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liver cirrhosis

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1760137

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