about
Manipulation of cellular GSH biosynthetic capacity via TAT-mediated protein transduction of wild-type or a dominant-negative mutant of glutamate cysteine ligase alters cell sensitivity to oxidant-induced cytotoxicityProtein-protein interaction antagonists as novel inhibitors of non-canonical polyubiquitylationHeterogeneous role of the glutathione antioxidant system in modulating the response of ESFT to fenretinide in normoxia and hypoxiaEffects of pluronic and doxorubicin on drug uptake, cellular metabolism, apoptosis and tumor inhibition in animal models of MDR cancers.Comparative evaluation of the treatment efficacy of suberoylanilide hydroxamic acid (SAHA) and paclitaxel in ovarian cancer cell lines and primary ovarian cancer cells from patients.Role of oxidative stress and intracellular glutathione in the sensitivity to apoptosis induced by proteasome inhibitor in thyroid cancer cells.Integrated analysis of DNA methylation and gene expression reveals specific signaling pathways associated with platinum resistance in ovarian cancerHypericins as potential leads for new therapeutics188Re-Liposome Can Induce Mitochondrial Autophagy and Reverse Drug Resistance for Ovarian Cancer: From Bench Evidence to Preliminary Clinical Proof-of-ConceptReport of a phase 1/2 study of a combination of azacitidine and cytarabine in acute myelogenous leukemia and high-risk myelodysplastic syndromesDrug resistance in cancer: principles of emergence and prevention.A Salmonella nanoparticle mimic overcomes multidrug resistance in tumours.Downregulation of cystine transporter xc by irinotecan in human head and neck cancer FaDu xenografts.Antitumor agents. 280. Multidrug resistance-selective desmosdumotin B analoguesReversal of multidrug resistance by magnetic Fe3O4 nanoparticle copolymerizating daunorubicin and MDR1 shRNA expression vector in leukemia cells.P-glycoprotein is not involved in pathway of anti-Fas/Fas-induced apoptosis in KBv200 cells.MDR1 siRNA loaded hyaluronic acid-based CD44 targeted nanoparticle systems circumvent paclitaxel resistance in ovarian cancer.Screening of deoxyribozyme with high reversal efficiency against multidrug resistance in breast carcinoma cells.Polymer genomics: an insight into pharmacology and toxicology of nanomedicinesNVP-TAE684 reverses multidrug resistance (MDR) in human osteosarcoma by inhibiting P-glycoprotein (PGP1) function.The ABC transporters MDR1 and MRP2: multiple functions in disposition of xenobiotics and drug resistance.Trametinib modulates cancer multidrug resistance by targeting ABCB1 transporterMultidrug-resistant cancer cells are preferential targets of the new antineoplastic lanthanum compound KP772 (FFC24).Cancer drug pan-resistance: pumps, cancer stem cells, quiescence, epithelial to mesenchymal transition, blocked cell death pathways, persisters or what?The emerging pharmacotherapeutic significance of the breast cancer resistance protein (ABCG2).Virtual screening of ABCC1 transporter nucleotidebinding domains as a therapeutic target in multidrug resistant cancer.Delivery of intracellular-acting biologics in pro-apoptotic therapies.Reactive oxygen species and antioxidant mechanisms in human tissues and their relation to malignancies.Tariquidar (XR9576): a P-glycoprotein drug efflux pump inhibitor.Reduced glutathione: a radioprotector or a modulator of DNA-repair activity?Pharmacokinetics and tolerability of NSC23925b, a novel P-glycoprotein inhibitor: preclinical study in mice and rats.Alteration of genomic responses to doxorubicin and prevention of MDR in breast cancer cells by a polymer excipient: pluronic P85.Radical decisions in cancer: redox control of cell growth and death.Histone deacetylase inhibitor PCI-24781 enhances chemotherapy-induced apoptosis in multidrug-resistant sarcoma cell lines.Inhibition of cystine uptake disrupts the growth of primary brain tumors.Prevention of MDR development in leukemia cells by micelle-forming polymeric surfactant.Increase in thiol oxidative stress via glutathione reductase inhibition as a novel approach to enhance cancer sensitivity to X-ray irradiationNovel strategies for reversing platinum resistance.Structure-activity relationships of tariquidar analogs as multidrug resistance modulators.Crystal structure of gamma-glutamylcysteine synthetase: insights into the mechanism of catalysis by a key enzyme for glutathione homeostasis.
P2860
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P2860
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Strategies for reversing drug resistance.
@ast
Strategies for reversing drug resistance.
@en
type
label
Strategies for reversing drug resistance.
@ast
Strategies for reversing drug resistance.
@en
prefLabel
Strategies for reversing drug resistance.
@ast
Strategies for reversing drug resistance.
@en
P2860
P356
P1433
P1476
Strategies for reversing drug resistance.
@en
P2093
Susan Bates
P2860
P2888
P304
P356
10.1038/SJ.ONC.1206951
P407
P577
2003-10-01T00:00:00Z