Identification and validation of novel small molecule disruptors of HuR-mRNA interaction. - Wikidata - wikimedia - TriplyDB

Identification and validation of novel small molecule disruptors of HuR-mRNA interaction.

Identification and validation of novel small molecule disruptors of HuR-mRNA interaction.

http://www.wikidata.org/entity/Q35573530

about

Hallmarks of cancer and AU-rich elements Current Evidence and Future Perspectives on HuR and Breast Cancer Development, Prognosis, and Treatment The fungal natural product azaphilone-9 binds to HuR and inhibits HuR-RNA interaction in vitro.The mRNA-binding protein HuR promotes hypoxia-induced chemoresistance through posttranscriptional regulation of the proto-oncogene PIM1 in pancreatic cancer cells.Identification of Small-Molecule Inhibitors of the HuR/RNA Interaction Using a Fluorescence Polarization Screening Assay Followed by NMR Validation Non-stoichiometric inhibition in integrated lead finding - a literature review.HuR Contributes to TRAIL Resistance by Restricting Death Receptor 4 Expression in Pancreatic Cancer Cells Dihydrotanshinone-I interferes with the RNA-binding activity of HuR affecting its post-transcriptional function.Inhibiting cytoplasmic accumulation of HuR synergizes genotoxic agents in urothelial carcinoma of the bladder.Impact of HuR inhibition by the small molecule MS-444 on colorectal cancer cell tumorigenesis.Targeting EPO and EPO receptor pathways in anemia and dysregulated erythropoiesis.Hu Antigen R (HuR) multimerization contributes to glioma disease progression.HuR-targeted small molecule inhibitor exhibits cytotoxicity towards human lung cancer cells.Identification of novel small molecule Beclin 1 mimetics activating autophagy.Activation of HuR downstream of p38 MAPK promotes cardiomyocyte hypertrophy.RNA Binding Protein as an Emerging Therapeutic Target for Cancer Prevention and Treatment.Interaction of RNA-binding protein HuR and miR-466i regulates GM-CSF expression.Regulation of HuR structure and function by dihydrotanshinone-I.Whole-transcriptome microarray analysis reveals regulation of Rab4 by RBM5 in neurons.CRISPR Knockout of the HuR Gene Causes a Xenograft Lethal Phenotype.Complex HuR function in pancreatic cancer cells.RNA-binding protein CUGBP1 regulates insulin secretion via activation of phosphodiesterase 3B in mice.Posttranscriptional Regulation of PARG mRNA by HuR Facilitates DNA Repair and Resistance to PARP Inhibitors.Messenger RNA Life-Cycle in Cancer Cells: Emerging Role of Conventional and Non-Conventional RNA-Binding Proteins?Expansion of cat-ELCCA for the Discovery of Small Molecule Inhibitors of the Pre-let-7-Lin28 RNA-Protein Interaction.Differential expression of RNA-binding proteins in bronchial epithelium of stable COPD patients Nicotine induces endothelial dysfunction and promotes atherosclerosis via GTPCH1

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Identification and validation of novel small molecule disruptors of HuR-mRNA interaction.

http://www.wikidata.org/entity/Q35573530

description

2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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name

Identification and validation of novel small molecule disruptors of HuR-mRNA interaction.

@ast

Identification and validation of novel small molecule disruptors of HuR-mRNA interaction.

@en

type

label

Identification and validation of novel small molecule disruptors of HuR-mRNA interaction.

@ast

Identification and validation of novel small molecule disruptors of HuR-mRNA interaction.

@en

prefLabel

Identification and validation of novel small molecule disruptors of HuR-mRNA interaction.

@ast

Identification and validation of novel small molecule disruptors of HuR-mRNA interaction.

@en

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ACS Chemical Biology

P1476

Identification and validation of novel small molecule disruptors of HuR-mRNA interaction.

@en

P2093

Benjamin Andrew Turner

http://www.w3.org/2001/XMLSchema#string

Dan A Dixon

http://www.w3.org/2001/XMLSchema#string

David Michael Wilson

http://www.w3.org/2001/XMLSchema#string

Jeffrey Aubé

http://www.w3.org/2001/XMLSchema#string

Jon A Tunge

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Lan Lan

http://www.w3.org/2001/XMLSchema#string

Liang Xu

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Peter McDonald

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Philip Gao

http://www.w3.org/2001/XMLSchema#string

Rebecca T Marquez

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P2860

Identification and mechanistic characterization of low-molecular-weight inhibitors for HuR

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

Posttranscriptional regulation of cancer traits by HuR

Multiple functions of the RNA-binding protein HuR in cancer progression, treatment responses and prognosis

Lentiviral vectors to probe and manipulate the Wnt signaling pathway

A novel high throughput biochemical assay to evaluate the HuR protein-RNA complex formation

HuR and mRNA stability

MicroRNA miR-34 inhibits human pancreatic cancer tumor-initiating cells

Design and synthesis of novel Gefitinib analogues with improved anti-tumor activity

A natural BH3 mimetic induces autophagy in apoptosis-resistant prostate cancer via modulating Bcl-2-Beclin1 interaction at endoplasmic reticulum.

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1476-1484

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scholarly article

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10.1021/CB500851U

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6

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10

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2015-03-17T00:00:00Z

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25750985

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4631057

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