Mechanism of tRNA-dependent editing in translational quality control
about
Idiosyncrasy and identity in the prokaryotic phe-system: Crystal structure ofE. coliphenylalanyl-tRNA synthetase complexed with phenylalanine and AMPMechanistic insights into cognate substrate discrimination during proofreading in translationThe Mode of Inhibitor Binding to Peptidyl-tRNA Hydrolase: Binding Studies and Structure Determination of Unbound and Bound Peptidyl-tRNA Hydrolase from Acinetobacter baumanniiMechanism of chiral proofreading during translation of the genetic codetRNA as an active chemical scaffold for diverse chemical transformationsRNA-assisted catalysis in a protein enzyme: The 2'-hydroxyl of tRNA(Thr) A76 promotes aminoacylation by threonyl-tRNA synthetaseSevere oxidative stress induces protein mistranslation through impairment of an aminoacyl-tRNA synthetase editing site.Oxidation of cellular amino acid pools leads to cytotoxic mistranslation of the genetic codeIs mitochondrial tRNA(phe) variant m.593T>C a synergistically pathogenic mutation in Chinese LHON families with m.11778G>A?Resampling and editing of mischarged tRNA prior to translation elongation.Naturally occurring aminoacyl-tRNA synthetases editing-domain mutations that cause mistranslation in Mycoplasma parasitesFidelity escape by the unnatural amino acid β-hydroxynorvaline: an efficient substrate for Escherichia coli threonyl-tRNA synthetase with toxic effects on growth.Substrate-mediated fidelity mechanism ensures accurate decoding of proline codons.Universal pathway for posttransfer editing reactions: insights from the crystal structure of TtPheRS with puromycinSpecificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.Pathogenic mechanism of a human mitochondrial tRNAPhe mutation associated with myoclonic epilepsy with ragged red fibers syndrome.Phenylalanyl-tRNA synthetase editing defects result in efficient mistranslation of phenylalanine codons as tyrosine.In vitro assays for the determination of aminoacyl-tRNA synthetase editing activity.Selection of tRNA charging quality control mechanisms that increase mistranslation of the genetic code.Quality control despite mistranslation caused by an ambiguous genetic codeAminoacylation of tRNA 2'- or 3'-hydroxyl by phosphoseryl- and pyrrolysyl-tRNA synthetases.Rewiring protein synthesis: From natural to synthetic amino acids.Mechanism of oxidant-induced mistranslation by threonyl-tRNA synthetase.Translation fidelity coevolves with longevity.G673 could be a novel mutational hot spot for intragenic suppressors of pheS5 lesion in Escherichia coli.Substrate and enzyme functional groups contribute to translational quality control by bacterial prolyl-tRNA synthetase.Mitochondrial phenylalanyl-tRNA synthetase mutations underlie fatal infantile Alpers encephalopathy.Substrate specificity and catalysis by the editing active site of Alanyl-tRNA synthetase from Escherichia coli.Regulation of mRNA Translation in Neurons-A Matter of Life and Death.Hydrolysis of non-cognate aminoacyl-adenylates by a class II aminoacyl-tRNA synthetase lacking an editing domain.The phylogenomic roots of modern biochemistry: origins of proteins, cofactors and protein biosynthesis.Identification of the nucleophilic factors and the productive complex for the editing reaction by leucyl-tRNA synthetase.Genome-Wide Quantification of the Effect of Gene Overexpression on Growth
P2860
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P2860
Mechanism of tRNA-dependent editing in translational quality control
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Mechanism of tRNA-dependent editing in translational quality control
@ast
Mechanism of tRNA-dependent editing in translational quality control
@en
type
label
Mechanism of tRNA-dependent editing in translational quality control
@ast
Mechanism of tRNA-dependent editing in translational quality control
@en
prefLabel
Mechanism of tRNA-dependent editing in translational quality control
@ast
Mechanism of tRNA-dependent editing in translational quality control
@en
P2860
P356
P1476
Mechanism of tRNA-dependent editing in translational quality control
@en
P2093
Michael Ibba
P2860
P356
10.1073/PNAS.0606272104
P407
P50
P577
2006-12-21T00:00:00Z