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Myosin-X and diseaseDirect Microtubule-Binding by Myosin-10 Orients Centrosomes toward Retraction Fibers and Subcortical Actin Clouds.The myosin X motor is optimized for movement on actin bundles.Antiparallel coiled-coil-mediated dimerization of myosin XA RIAM/lamellipodin-talin-integrin complex forms the tip of sticky fingers that guide cell migrationMyosin-X functions in polarized epithelial cells.Adducin-1 is essential for mitotic spindle assembly through its interaction with myosin-X.Mutant p53-associated myosin-X upregulation promotes breast cancer invasion and metastasis.Actin dynamics in growth cone motility and navigationMyosin-X facilitates Shigella-induced membrane protrusions and cell-to-cell spread.Novel microscopy-based screening method reveals regulators of contact-dependent intercellular transfer.Harnessing molecular motors for nanoscale pulldown in live cells.Activated full-length myosin-X moves processively on filopodia with large steps toward diverse two-dimensional directionsImportant roles of Vilse in dendritic architecture and synaptic plasticityMyosin-10 produces its power-stroke in two phases and moves processively along a single actin filament under low load.Non-muscle myosins in tumor progression, cancer cell invasion, and metastasis.Cadherin-dependent filopodia control preimplantation embryo compaction.HOXA5 inhibits metastasis via regulating cytoskeletal remodelling and associates with prolonged survival in non-small-cell lung carcinomaOrchestration of microtubules and the actin cytoskeleton in trichome cell shape determination by a plant-unique kinesin.Headless Myo10 is a negative regulator of full-length Myo10 and inhibits axon outgrowth in cortical neurons.Myosin X dimerization and its impact on cellular functions.Porf-2 Inhibits Neural Stem Cell Proliferation Through Wnt/β-Catenin Pathway by Its GAP Domain.Myosin MyTH4-FERM structures highlight important principles of convergent evolution.Competition between Coiled-Coil Structures and the Impact on Myosin-10 Bundle Selection.DPP6 regulation of dendritic morphogenesis impacts hippocampal synaptic development.PDZD7-MYO7A complex identified in enriched stereocilia membranes.Macrophages promote matrix protrusive and invasive function of breast cancer cells via MIP-1β dependent upregulation of MYO3A gene in breast cancer cellsMyosin X and its motorless isoform differentially modulate dendritic spine development by regulating trafficking and retention of vasodilator-stimulated phosphoprotein.MyTH4-FERM myosins have an ancient and conserved role in filopod formationUltrastructure of protrusive actin filament arrays.The cortical acto-Myosin network: from diffusion barrier to functional gateway in the transport of neurosecretory vesicles to the plasma membrane.Intrinsic Disorder in the Kinesin Superfamily.Control of cell migration through mRNA localization and local translation.The Cytoskeleton and Its Regulation by Calcium and Protons.Structural Basis of Cargo Recognition by Unconventional Myosins in Cellular Trafficking.The Canonical Notch Signaling Pathway: Structural and Biochemical Insights into Shape, Sugar, and Force.Specialized filopodia direct long-range transport of SHH during vertebrate tissue patterning.Myosin X is recruited to nascent focal adhesions at the leading edge and induces multi-cycle filopodial elongation.Linking actin networks and cell membrane via a reaction-diffusion-elastic description of nonlinear filopodia initiation.Myosin-X knockout is semi-lethal and demonstrates that myosin-X functions in neural tube closure, pigmentation, hyaloid vasculature regression, and filopodia formation.
P2860
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P2860
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Myosin-X: a MyTH-FERM myosin at the tips of filopodia
@ast
Myosin-X: a MyTH-FERM myosin at the tips of filopodia
@en
type
label
Myosin-X: a MyTH-FERM myosin at the tips of filopodia
@ast
Myosin-X: a MyTH-FERM myosin at the tips of filopodia
@en
prefLabel
Myosin-X: a MyTH-FERM myosin at the tips of filopodia
@ast
Myosin-X: a MyTH-FERM myosin at the tips of filopodia
@en
P2860
P356
P1476
Myosin-X: a MyTH-FERM myosin at the tips of filopodia
@en
P2093
Michael L Kerber
P2860
P304
P356
10.1242/JCS.023549
P407
P577
2011-11-01T00:00:00Z