Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) in combination with the Apogossypol derivative BI-97C1 (Sabutoclax) improves therapeutic efficacy in low CAR colorectal cancer cells
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Bcl-2 antagonists: a proof of concept for CLL therapyTargeting the Bcl-2 family for cancer therapysIL-24 peptide, a human interleukin-24 isoform, induces mitochondrial-mediated apoptosis in human cancer cells.Reversing translational suppression and induction of toxicity in pancreatic cancer cells using a chemoprevention gene therapy approachEnhanced prostate cancer gene transfer and therapy using a novel serotype chimera cancer terminator virus (Ad.5/3-CTV).Chapter One---Cancer terminator viruses and approaches for enhancing therapeutic outcomes.Gene Therapies for Cancer: Strategies, Challenges and Successes.Pancreatic Cancer Combination Therapy Using a BH3 Mimetic and a Synthetic Tetracycline.Mcl-1 is an important therapeutic target for oral squamous cell carcinomas.Sabutoclax, a Mcl-1 antagonist, inhibits tumorigenesis in transgenic mouse and human xenograft models of prostate cancerMDA-7/IL-24: multifunctional cancer killing cytokineInhibitors of the anti-apoptotic Bcl-2 proteins: a patent review.MDA-7/IL-24 functions as a tumor suppressor gene in vivo in transgenic mouse models of breast cancer.Suppression of Her2/Neu mammary tumor development in mda-7/IL-24 transgenic miceHistone deacetylase inhibitors interact with melanoma differentiation associated-7/interleukin-24 to kill primary human glioblastoma cells.Combinatorial strategies based on CRAd-IL24 and CRAd-ING4 virotherapy with anti-angiogenesis treatment for ovarian cancer.TAT-IL-24-KDEL-induced apoptosis is inhibited by survivin but restored by the small molecular survivin inhibitor, YM155, in cancer cells.Combining histone deacetylase inhibitors with MDA-7/IL-24 enhances killing of renal carcinoma cellsCell-penetrating and endoplasmic reticulum-locating TAT-IL-24-KDEL fusion protein induces tumor apoptosis.Detecting Tumor Metastases: The Road to Therapy Starts Here.Optimisation of the mRNA secondary structure to improve the expression of interleukin-24 (IL-24) in Escherichia coli.Enhanced tumor growth inhibition by mesenchymal stem cells derived from iPSCs with targeted integration of interleukin24 into rDNA loci.Therapy of pancreatic cancer via an EphA2 receptor-targeted delivery of gemcitabine.Biological nanoparticles carrying the Hmda-7 gene are effective in inhibiting pancreatic cancer in vitro and in vivo.Cancer Terminator Viruses (CTV): A Better Solution for Viral-Based Therapy of Cancer.Soluble expression, rapid purification, and characterization of human interleukin-24 (IL-24) using a MBP-SUMO dual fusion system in Escherichia coli.Improving the mda-7/IL-24 refolding and purification process using optimized culture conditions based on the structure characteristics of inclusion bodies
P2860
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P2860
Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) in combination with the Apogossypol derivative BI-97C1 (Sabutoclax) improves therapeutic efficacy in low CAR colorectal cancer cells
description
2012 nî lūn-bûn
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2012年の論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年论文
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2012年论文
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2012年论文
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name
Enhanced delivery of mda-7/IL- ...... ow CAR colorectal cancer cells
@ast
Enhanced delivery of mda-7/IL- ...... ow CAR colorectal cancer cells
@en
type
label
Enhanced delivery of mda-7/IL- ...... ow CAR colorectal cancer cells
@ast
Enhanced delivery of mda-7/IL- ...... ow CAR colorectal cancer cells
@en
prefLabel
Enhanced delivery of mda-7/IL- ...... ow CAR colorectal cancer cells
@ast
Enhanced delivery of mda-7/IL- ...... ow CAR colorectal cancer cells
@en
P2093
P2860
P50
P356
P1476
Enhanced delivery of mda-7/IL- ...... ow CAR colorectal cancer cells
@en
P2093
Belal Azab
Bridget A Quinn
Devanand Sarkar
Igor P Dmitriev
John C Reed
Maurizio Pellecchia
Michael Hedvat
Paul B Fisher
Siddik Sarkar
Steven Grant
P2860
P304
P356
10.1002/JCP.22947
P577
2012-05-01T00:00:00Z