Dual cancer-specific targeting strategy cures primary and distant breast carcinomas in nude mice. - Wikidata - wikimedia - TriplyDB

Dual cancer-specific targeting strategy cures primary and distant breast carcinomas in nude mice.

Dual cancer-specific targeting strategy cures primary and distant breast carcinomas in nude mice.

http://www.wikidata.org/entity/Q34048220

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Developing an effective gene therapy for prostate cancer: New technologies with potential to translate from the laboratory into the clinic Therapy of prostate cancer using a novel cancer terminator virus and a small molecule BH-3 mimetic Recombinant interleukin-24 lacks apoptosis-inducing properties in melanoma cells.Cisplatin enhances protein kinase R-like endoplasmic reticulum kinase- and CD95-dependent melanoma differentiation-associated gene-7/interleukin-24-induced killing in ovarian carcinoma cells Potent anti-tumor effects of a dual specific oncolytic adenovirus expressing apoptin in vitro and in vivo Chemical modification with high molecular weight polyethylene glycol reduces transduction of hepatocytes and increases efficacy of intravenously delivered oncolytic adenovirus Recognition-mediated activation of therapeutic gold nanoparticles inside living cells Eradication of therapy-resistant human prostate tumors using an ultrasound-guided site-specific cancer terminator virus delivery approach.Characterization of the canine mda-7 gene, transcripts and expression patterns.Tumour suppressor function of MDA-7/IL-24 in human breast cancer The development of MDA-7/IL-24 as a cancer therapeutic Tumor-specific imaging through progression elevated gene-3 promoter-driven gene expression In vivo gene delivery by embryonic-stem-cell-derived astrocytes for malignant gliomas.Construction of doxycyline-dependent mini-HIV-1 variants for the development of a virotherapy against leukemias Enhanced prostate cancer gene transfer and therapy using a novel serotype chimera cancer terminator virus (Ad.5/3-CTV).Targeting breast cancer-initiating/stem cells with melanoma differentiation-associated gene-7/interleukin-24.Chapter One---Cancer terminator viruses and approaches for enhancing therapeutic outcomes.Gene Therapies for Cancer: Strategies, Challenges and Successes.mda-7/IL-24: a unique member of the IL-10 gene family promoting cancer-targeted toxicity.Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) in combination with the Apogossypol derivative BI-97C1 (Sabutoclax) improves therapeutic efficacy in low CAR colorectal cancer cells mda-7/IL-24: multifunctional cancer-specific apoptosis-inducing cytokine Strategy for reversing resistance to a single anticancer agent in human prostate and pancreatic carcinomas Conditionally replicating adenoviruses for cancer treatment.MDA-7/IL-24: multifunctional cancer killing cytokine Ionizing radiation enhances adenoviral vector expressing mda-7/IL-24-mediated apoptosis in human ovarian cancer.Oncolytic adenovirus armed with IL-24 inhibits the growth of breast cancer in vitro and in vivo.MDA-7/IL-24 functions as a tumor suppressor gene in vivo in transgenic mouse models of breast cancer.Suppression of Her2/Neu mammary tumor development in mda-7/IL-24 transgenic mice CD47-retargeted oncolytic adenovirus armed with melanoma differentiation-associated gene-7/interleukin-24 suppresses in vivo leukemia cell growth Melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24): novel gene therapeutic for metastatic melanoma.Autocrine regulation of mda-7/IL-24 mediates cancer-specific apoptosis.Melanoma differentiation associated gene-7 (mda-7)/IL-24: a 'magic bullet' for cancer therapy?mda-7/IL-24 Induces Cell Death in Neuroblastoma through a Novel Mechanism Involving AIF and ATM.Histone deacetylase inhibitors interact with melanoma differentiation associated-7/interleukin-24 to kill primary human glioblastoma cells.Combinatorial strategies based on CRAd-IL24 and CRAd-ING4 virotherapy with anti-angiogenesis treatment for ovarian cancer.Selected approaches for rational drug design and high throughput screening to identify anti-cancer molecules IL-24: a classic cytokine and/or a potential cure for cancer?Armed replicating adenoviruses for cancer virotherapy.Clinical applications of mouse models for breast cancer engaging HER2/neu.Conditionally replicating adenoviruses carrying mda-7/IL-24 for cancer therapy.

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Dual cancer-specific targeting strategy cures primary and distant breast carcinomas in nude mice.

http://www.wikidata.org/entity/Q34048220

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2005 nî lūn-bûn

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2005 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2005 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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Dual cancer-specific targeting ...... reast carcinomas in nude mice.

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Dual cancer-specific targeting ...... reast carcinomas in nude mice.

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Dual cancer-specific targeting ...... reast carcinomas in nude mice.

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Dual cancer-specific targeting ...... reast carcinomas in nude mice.

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Dual cancer-specific targeting ...... reast carcinomas in nude mice.

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Dual cancer-specific targeting ...... reast carcinomas in nude mice.

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Dual cancer-specific targeting ...... reast carcinomas in nude mice.

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Dual cancer-specific targeting ...... reast carcinomas in nude mice.

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Dual cancer-specific targeting ...... reast carcinomas in nude mice.

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Dual cancer-specific targeting ...... reast carcinomas in nude mice.

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Devanand Sarkar

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Eun Sook Park

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Nicolaq Vozhilla

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Pankaj Gupta

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Paul B Fisher

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Zao-Zhong Su

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P2860

The cancer growth suppressor gene mda-7 selectively induces apoptosis in human breast cancer cells and inhibits tumor growth in nude mice

mda-7/IL-24, a novel cancer selective apoptosis inducing cytokine gene: from the laboratory into the clinic

Interleukin-10 and related cytokines and receptors

Melanoma differentiation associated gene-7/interleukin-24 promotes tumor cell-specific apoptosis through both secretory and nonsecretory pathways

PEG-3, a nontransforming cancer progression gene, is a positive regulator of cancer aggressiveness and angiogenesis

Potential molecular mechanism for rodent tumorigenesis: mutational generation of Progression Elevated Gene-3 (PEG-3)

Cancer statistics, 2005

AP-1: a double-edged sword in tumorigenesis

Targeting gene expression selectively in cancer cells by using the progression-elevated gene-3 promoter.

Mda-7, a novel melanoma differentiation associated gene with promise for cancer gene therapy.

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14034-14039

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102

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