Blood platelets express high levels of the pp60c-src-specific tyrosine kinase activity.
about
Coordinate interactions of Csk, Src, and Syk kinases with [alpha]IIb[beta]3 initiate integrin signaling to the cytoskeletonIdentification of a human gene (HCK) that encodes a protein-tyrosine kinase and is expressed in hemopoietic cellsIdentification, cloning, and expression of a cytosolic megakaryocyte protein-tyrosine-phosphatase with sequence homology to cytoskeletal protein 4.1Molecular identification of a major palmitoylated erythrocyte membrane protein containing the src homology 3 motifMembrane glycoprotein IV (CD36) is physically associated with the Fyn, Lyn, and Yes protein-tyrosine kinases in human plateletsEvidence for a role for tyrosine phosphorylation of phospholipase C gamma 2 in collagen-induced platelet cytosolic calcium mobilizationPutative tyrosine kinases expressed in K-562 human leukemia cellsTwo additional protein-tyrosine kinases expressed in human lung: fourth member of the fibroblast growth factor receptor family and an intracellular protein-tyrosine kinaseTwo isoforms of murine hck, generated by utilization of alternative translational initiation codons, exhibit different patterns of subcellular localizationSelective expression of a protein-tyrosine kinase, p56lyn, in hematopoietic cells and association with production of human T-cell lymphotropic virus type IA noncatalytic domain conserved among cytoplasmic protein-tyrosine kinases modifies the kinase function and transforming activity of Fujinami sarcoma virus P130gag-fpsThe hunting of the SrcRegulation of platelet plasma membrane Ca2+-ATPase by cAMP-dependent and tyrosine phosphorylationc-Src association with and phosphorylation of p58gag, a membrane- and microfilament-associated retroviral Gag-like protein in a xenotransplantable rat mammary tumor.Association of the amino-terminal half of c-Src with focal adhesions alters their properties and is regulated by phosphorylation of tyrosine 527.The sites of phosphorylation by protein kinase C and an intact SH2 domain are required for the enhanced response to beta-adrenergic agonists in cells overexpressing c-srcpp60c-src tyrosine kinase, myristylation, and modulatory domains are required for enhanced mitogenic responsiveness to epidermal growth factor seen in cells overexpressing c-srcAugmented mitogenic responsiveness to epidermal growth factor in murine fibroblasts that overexpress pp60c-src.Reduced tyrosine kinase specific activity is associated with hypophosphorylation of pp60c-src in cells infected with avian erythroblastosis virus.Platelet adhesion to collagen via the alpha 2 beta 1 integrin under arterial flow conditions causes rapid tyrosine phosphorylation of pp125FAK.Analysis of cDNAs of the proto-oncogene c-src: heterogeneity in 5' exons and possible mechanism for the genesis of the 3' end of v-src.Isolation of a src homology 2-containing tyrosine phosphataseA dominant gain-of-function mutation in universal tyrosine kinase SRC causes thrombocytopenia, myelofibrosis, bleeding, and bone pathologies.Agonist-induced ADP-ribosylation of a cytosolic protein in human plateletsAcquisition of transforming properties by FYN, a normal SRC-related human gene.c-src gene product in developing rat brain is enriched in nerve growth cone membranesIdentification and subcellular localization of proteins that are rapidly phosphorylated in tyrosine in response to colony-stimulating factor 1Thrombin treatment induces rapid changes in tyrosine phosphorylation in platelets.Tyrosine-specific protein phosphorylation is regulated by glycoprotein IIb-IIIa in platelets.Thrombin-stimulated immunoprecipitation of phosphatidylinositol 3-kinase from human platelets.Regulation of pp56lck during T-cell activation: functional implications for the src-like protein tyrosine kinasesSrc inhibitors in the treatment of metastatic bone disease: rationale and clinical dataTranslocation of the FGR protein-tyrosine kinase as a consequence of neutrophil activation.Isolation and sequence of a cDNA corresponding to a src-related gene expressed in murine hemopoietic cells.Additional member of the protein-tyrosine kinase family: the src- and lck-related protooncogene c-tkl.Activation of pp60c-src protein kinase activity in human colon carcinoma.Differential expression and regulation of the c-src and c-fgr protooncogenes in myelomonocytic cells.Negative regulation of Gq-mediated pathways in platelets by G(12/13) pathways through Fyn kinase.Terminal neuroendocrine differentiation of human prostate carcinoma cells in response to increased intracellular cyclic AMPTyrosine phosphorylation of the human serotonin transporter: a role in the transporter stability and function.
P2860
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P2860
Blood platelets express high levels of the pp60c-src-specific tyrosine kinase activity.
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
1986年论文
@zh
1986年论文
@zh-cn
name
Blood platelets express high levels of the pp60c-src-specific tyrosine kinase activity.
@ast
Blood platelets express high levels of the pp60c-src-specific tyrosine kinase activity.
@en
type
label
Blood platelets express high levels of the pp60c-src-specific tyrosine kinase activity.
@ast
Blood platelets express high levels of the pp60c-src-specific tyrosine kinase activity.
@en
prefLabel
Blood platelets express high levels of the pp60c-src-specific tyrosine kinase activity.
@ast
Blood platelets express high levels of the pp60c-src-specific tyrosine kinase activity.
@en
P2093
P2860
P356
P1476
Blood platelets express high levels of the pp60c-src-specific tyrosine kinase activity.
@en
P2093
P2860
P304
P356
10.1073/PNAS.83.4.852
P407
P577
1986-02-01T00:00:00Z