Augmented mitogenic responsiveness to epidermal growth factor in murine fibroblasts that overexpress pp60c-src.
about
Src family kinases negatively regulate platelet-derived growth factor alpha receptor-dependent signaling and disease progressionSrc phosphorylation of the epidermal growth factor receptor at novel sites mediates receptor interaction with Src and P85 alphaTyrosine phosphorylation of selected secretory carrier membrane proteins, SCAMP1 and SCAMP3, and association with the EGF receptor.Tyrosine kinase signalling in breast cancer: epidermal growth factor receptor and c-Src interactions in breast cancer.The hunting of the SrcExpression of RALT, a feedback inhibitor of ErbB receptors, is subjected to an integrated transcriptional and post-translational controlHistone deacetylase 3 binds to and regulates the multifunctional transcription factor TFII-IModulation of the SH2 binding specificity and kinase activity of Src by tyrosine phosphorylation within its SH2 domainBrk, a breast tumor-derived non-receptor protein-tyrosine kinase, sensitizes mammary epithelial cells to epidermal growth factorOverexpression of c-src enhances beta-adrenergic-induced cAMP accumulation'Srcasm: a novel Src activating and signaling moleculeA role for Src in signal relay by the platelet-derived growth factor alpha receptorThe C terminus of c-Src inhibits breast tumor cell growth by a kinase-independent mechanism.Cas mediates transcriptional activation of the serum response element by Src.Dissection of the molecular basis of pp60(v-src) induced gating of connexin 43 gap junction channels.Src phosphorylates EAST, a novel EGF receptor-associated protein.Requirement for c-Src catalytic activity and the SH3 domain in platelet-derived growth factor BB and epidermal growth factor mitogenic signaling.The Src SH3 domain is required for DNA synthesis induced by platelet-derived growth factor and epidermal growth factor.Crk interacts with tyrosine-phosphorylated p116 upon T cell activation.Involvement of pp60c-src with two major signaling pathways in human breast cancer.STAT5b, a Mediator of Synergism between c-Src and the Epidermal Growth Factor Receptor.Synergistic promotion of c-Src activation and cell migration by Cas and AND-34/BCAR3.Src family kinases mediate epidermal growth factor receptor signaling from lipid rafts in breast cancer cells.Phosphorylation and activation of epidermal growth factor receptors in cells transformed by the src oncogeneTyrosine phosphorylation of a 120-kilodalton pp60src substrate upon epidermal growth factor and platelet-derived growth factor receptor stimulation and in polyomavirus middle-T-antigen-transformed cells.Transformation by pp60src or stimulation of cells with epidermal growth factor induces the stable association of tyrosine-phosphorylated cellular proteins with GTPase-activating protein.Tyrosine phosphorylation of three cellular proteins correlates with transformation of rat 1 cells by pp60src.c-Src regulates the simultaneous rearrangement of actin cytoskeleton, p190RhoGAP, and p120RasGAP following epidermal growth factor stimulationA protein that is highly related to GTPase-activating protein-associated p62 complexes with phospholipase C gammaThe sites of phosphorylation by protein kinase C and an intact SH2 domain are required for the enhanced response to beta-adrenergic agonists in cells overexpressing c-srcConstitutive phosphorylation of the receptor for insulinlike growth factor I in cells transformed by the src oncogeneInhibition of epidermal growth factor receptor biosynthesis caused by the src oncogene product, pp60v-srcpp60c-src tyrosine kinase, myristylation, and modulatory domains are required for enhanced mitogenic responsiveness to epidermal growth factor seen in cells overexpressing c-srcPhosphotyrosine (p-Tyr)-dependent and -independent mechanisms of p190 RhoGAP-p120 RasGAP interaction: Tyr 1105 of p190, a substrate for c-Src, is the sole p-Tyr mediator of complex formationPotentiation of epidermal growth factor receptor-mediated oncogenesis by c-Src: implications for the etiology of multiple human cancersTyrosine phosphorylation of G protein alpha subunits by pp60c-srcMechanism of biological synergy between cellular Src and epidermal growth factor receptorPhosphotyrosine phosphatase activity associated with c-Src in large multimeric complexes isolated from adrenal medullary chromaffin cells.A novel negative imaging technique for accurate localization of stainable proteins on complex two-dimensional autoradiograms.Characterization of human epidermal growth factor receptor and c-Src interactions in human breast tumor cells.
P2860
Q22253382-16BA31A7-CDBC-4821-B151-80841B341A86Q24328857-A59DB376-F439-48DB-B96D-CEE66B6A6B36Q24648808-C49F8A5C-4BAA-43C7-9148-62104A61F2AEQ24803054-D9531A91-4D6A-4E5D-A195-70761F00D966Q28199081-11D94F96-4A00-4D29-8C9E-918C7D50036EQ28201580-47B2F1EF-DF64-462E-8C5D-2EDDC37A758AQ28210037-68BA09ED-25E1-46BD-952D-45435FBCC72BQ28280523-9D8C1E09-3EBF-4424-8F3A-4AFC474E5B2EQ28298083-78909A4F-5B52-4948-85FF-216B1A1FDD79Q28323490-5EC37539-D946-4FDE-8695-55FC62AD4461Q28505622-F7548DA0-846B-4775-8B15-7CE09B0E2613Q28645730-82FB5885-0063-425A-939D-96CD9305AE75Q30164215-0A84BD72-9912-437C-AE69-86DC52B7E5BCQ30175350-8B815D58-CCCA-4B9C-B52D-CBA610B8D4B8Q30175829-D2B12C68-BE89-4A88-AF81-C4ABB38F631AQ30176069-17CC5ADD-E41A-43A1-9FA2-EB1ABFA3BFF9Q30176895-96331DA5-9BDB-447B-946C-6E876CC802B2Q30176898-CF7C20A2-B747-4269-A5A4-302E30AF758AQ30193645-F41DBCC8-6A02-4004-8F80-DB3E4E3527D8Q30194582-4AC5D29B-DA91-4378-94BA-1B6BA01D275CQ30310214-C34B9E15-2B2E-4F45-B7E5-B417E8C0AB68Q30310839-7ED3D98D-E1DF-46BF-A05D-3E1FAC5A69ABQ30424531-8582DC7A-6BB5-42F4-AC1C-9957BC39B4D7Q30441810-83714538-78F7-407C-AFB0-077DC9ECE908Q30441876-67347DD5-F32E-4046-AD82-79F1AE0A7856Q30441879-C2CE2093-6CBF-4741-B03B-C558324C5420Q30442121-C3512B37-16F7-4003-9A14-152A15386DCAQ30442226-F8412B44-A0A7-4D63-9E38-4F11AD255AD2Q30450210-7FB10AB5-BEAC-4635-A7EA-2AEDE2647E1EQ30450277-4E61FB73-06D6-430C-BBEF-A1B7AD9E0681Q30450353-4266B0E7-51F9-44FB-99CC-BF5EC72D2435Q30450370-7CCC547C-AE16-447C-8418-378FA7338547Q30450399-CA562C23-C877-4933-8AD0-19BEDE49A852Q30453620-11D54C63-2825-422B-829D-3AD4E2B11E76Q30453944-F1E89F99-81E5-4514-A59D-BCF99CE7138BQ30454096-8284AB15-63B1-44BF-B4A5-73AF599E2439Q30454480-01581E59-6D35-4F62-8B1D-570122BA0CC5Q30471144-89FC897E-C0B6-4FCB-B312-2FBAE0D55F8AQ30471511-2AC08049-AB0C-41D8-BFAD-2E95DD9F84D2Q30472067-99CB335F-F070-43C2-91FA-D31C17D32212
P2860
Augmented mitogenic responsiveness to epidermal growth factor in murine fibroblasts that overexpress pp60c-src.
description
1988 nî lūn-bûn
@nan
1988 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
Augmented mitogenic responsive ...... ts that overexpress pp60c-src.
@ast
Augmented mitogenic responsive ...... ts that overexpress pp60c-src.
@en
type
label
Augmented mitogenic responsive ...... ts that overexpress pp60c-src.
@ast
Augmented mitogenic responsive ...... ts that overexpress pp60c-src.
@en
prefLabel
Augmented mitogenic responsive ...... ts that overexpress pp60c-src.
@ast
Augmented mitogenic responsive ...... ts that overexpress pp60c-src.
@en
P2093
P2860
P356
P1476
Augmented mitogenic responsive ...... ts that overexpress pp60c-src.
@en
P2093
D K Luttrell
L M Luttrell
S J Parsons
P2860
P304
P356
10.1128/MCB.8.1.497
P407
P577
1988-01-01T00:00:00Z