Cleavage and activation of the severe acute respiratory syndrome coronavirus spike protein by human airway trypsin-like protease
about
TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike proteinMechanisms of coronavirus cell entry mediated by the viral spike proteinDecoding protein networks during virus entry by quantitative proteomicsDiscovery of Critical Residues for Viral Entry and Inhibition through Structural Insight of HIV-1 Fusion Inhibitor CP621-652Fusion of Enveloped Viruses in Endosomes.Factors determining human-to-human transmissibility of zoonotic pathogens via contactInfluenza and SARS-coronavirus activating proteases TMPRSS2 and HAT are expressed at multiple sites in human respiratory and gastrointestinal tractsA decade after SARS: strategies for controlling emerging coronavirusesAbelson Kinase Inhibitors Are Potent Inhibitors of Severe Acute Respiratory Syndrome Coronavirus and Middle East Respiratory Syndrome Coronavirus Fusion.Ebola virus and severe acute respiratory syndrome coronavirus display late cell entry kinetics: evidence that transport to NPC1+ endolysosomes is a rate-defining stepProteolytic activation of the SARS-coronavirus spike protein: cutting enzymes at the cutting edge of antiviral research.DESC1 and MSPL activate influenza A viruses and emerging coronaviruses for host cell entry.Exposure to ozone modulates human airway protease/antiprotease balance contributing to increased influenza A infectionThe host protease TMPRSS2 plays a major role in in vivo replication of emerging H7N9 and seasonal influenza viruses.Structure, Function, and Evolution of Coronavirus Spike Proteins.The epitope and neutralization mechanism of AVFluIgG01, a broad-reactive human monoclonal antibody against H5N1 influenza virus.Host cell entry of Middle East respiratory syndrome coronavirus after two-step, furin-mediated activation of the spike protein.Protease inhibitors targeting coronavirus and filovirus entryCathepsin B & L are not required for ebola virus replicationThe role of viral population diversity in adaptation of bovine coronavirus to new host environmentsDifferential sensitivity of bat cells to infection by enveloped RNA viruses: coronaviruses, paramyxoviruses, filoviruses, and influenza viruses.Coronavirus cell entry occurs through the endo-/lysosomal pathway in a proteolysis-dependent manner.Host cell proteases: Critical determinants of coronavirus tropism and pathogenesisReady, set, fuse! The coronavirus spike protein and acquisition of fusion competenceSimultaneous treatment of human bronchial epithelial cells with serine and cysteine protease inhibitors prevents severe acute respiratory syndrome coronavirus entry.Respiratory protease/antiprotease balance determines susceptibility to viral infection and can be modified by nutritional antioxidantsCleavage activation of the human-adapted influenza virus subtypes by matriptase reveals both subtype and strain specificities.Different residues in the SARS-CoV spike protein determine cleavage and activation by the host cell protease TMPRSS2.Development of novel entry inhibitors targeting emerging viruses.The spike protein of the emerging betacoronavirus EMC uses a novel coronavirus receptor for entry, can be activated by TMPRSS2, and is targeted by neutralizing antibodies.Identification of the Fusion Peptide-Containing Region in Betacoronavirus Spike GlycoproteinsCell Surface Human Airway Trypsin-Like Protease Is Lost During Squamous Cell Carcinogenesis.Stability of bovine coronavirus on lettuce surfaces under household refrigeration conditions.TMPRSS2 is an activating protease for respiratory parainfluenza viruses.Middle East respiratory syndrome coronavirus infection mediated by the transmembrane serine protease TMPRSS2.High TMPRSS11D protein expression predicts poor overall survival in non-small cell lung cancer.Transmembrane serine protease TMPRSS2 activates hepatitis C virus infection.Human airway trypsin-like protease, a serine protease involved in respiratory diseases.TMPRSS2 activates the human coronavirus 229E for cathepsin-independent host cell entry and is expressed in viral target cells in the respiratory epithelium.Identification of the first synthetic inhibitors of the type II transmembrane serine protease TMPRSS2 suitable for inhibition of influenza virus activation.
P2860
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P2860
Cleavage and activation of the severe acute respiratory syndrome coronavirus spike protein by human airway trypsin-like protease
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Cleavage and activation of the ...... n airway trypsin-like protease
@ast
Cleavage and activation of the ...... n airway trypsin-like protease
@en
type
label
Cleavage and activation of the ...... n airway trypsin-like protease
@ast
Cleavage and activation of the ...... n airway trypsin-like protease
@en
prefLabel
Cleavage and activation of the ...... n airway trypsin-like protease
@ast
Cleavage and activation of the ...... n airway trypsin-like protease
@en
P2093
P2860
P50
P921
P356
P1433
P1476
Cleavage and activation of the ...... n airway trypsin-like protease
@en
P2093
Daniela Niemeyer
Elizabeth J Soilleux
Imke Steffen
Inga Nehlmeier
Stephanie Bertram
P2860
P304
13363-13372
P356
10.1128/JVI.05300-11
P407
P50
P577
2011-10-12T00:00:00Z