Deprotonation of the Schiff base of rhodopsin is obligate in the activation of the G protein.
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Mechanisms of opsin activationCo-expression of VAL- and TMT-opsins uncovers ancient photosensory interneurons and motorneurons in the vertebrate brainThe role of the lipid matrix for structure and function of the GPCR rhodopsin.Microsecond time-resolved circular dichroism of rhodopsin photointermediates.Fourier transform infrared studies of active-site-methylated rhodopsin. Implications for chromophore-protein interaction, transducin activation, and the reaction pathway.Time-resolved rhodopsin activation currents in a unicellular expression system.Glutamic acid-113 serves as the retinylidene Schiff base counterion in bovine rhodopsin.G protein-coupled receptor rhodopsin: a prospectus.Opsins with mutations at the site of chromophore attachment constitutively activate transducin but are not phosphorylated by rhodopsin kinase.Normal and mutant rhodopsin activation measured with the early receptor current in a unicellular expression system.Photochemistry of methylated rhodopsins.Two different forms of metarhodopsin II: Schiff base deprotonation precedes proton uptake and signaling stateProtonation states of membrane-embedded carboxylic acid groups in rhodopsin and metarhodopsin II: a Fourier-transform infrared spectroscopy study of site-directed mutants.Conformational states and dynamics of rhodopsin in micelles and bilayers.Insights into the activation mechanism of the visual receptor rhodopsin.Studies of rhodopsin and bacteriorhodopsin using modified retinals.Temperature dependence of G-protein activation in photoreceptor membranes. Transient extra metarhodopsin II on bovine disk membranes.Photolysis of rhodopsin results in deprotonation of its retinal Schiff's base prior to formation of metarhodopsin II.pKa of the protonated Schiff base of bovine rhodopsin. A study with artificial pigments.The pKa of the protonated Schiff bases of gecko cone and octopus visual pigments.Origin and control of the dominant time constant of salamander cone photoreceptors.Differential rhodopsin regeneration in photoreceptor membranes is correlated with variations in membrane properties.Schiff-base deprotonation is mandatory for light-dependent rhodopsin phosphorylation.Magic angle spinning NMR studies on the metarhodopsin II intermediate of bovine rhodopsin: evidence for an unprotonated Schiff base.Absorption and Emission Spectroscopic Investigation of Thermal Dynamics and Photo-Dynamics of the Rhodopsin Domain of the Rhodopsin-Guanylyl Cyclase from the Nematophagous Fungus Catenaria anguillulae.Structural models of the photointermediates in the rhodopsin photocascade, lumirhodopsin, metarhodopsin I, and metarhodopsin II.The effects of amino acid replacements of glycine 121 on transmembrane helix 3 of rhodopsin.Signaling states of rhodopsin. Retinal provides a scaffold for activating proton transfer switches.Mutation of the fourth cytoplasmic loop of rhodopsin affects binding of transducin and peptides derived from the carboxyl-terminal sequences of transducin alpha and gamma subunits.
P2860
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P2860
Deprotonation of the Schiff base of rhodopsin is obligate in the activation of the G protein.
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
1986年论文
@zh
1986年论文
@zh-cn
name
Deprotonation of the Schiff ba ...... e activation of the G protein.
@ast
Deprotonation of the Schiff ba ...... e activation of the G protein.
@en
type
label
Deprotonation of the Schiff ba ...... e activation of the G protein.
@ast
Deprotonation of the Schiff ba ...... e activation of the G protein.
@en
prefLabel
Deprotonation of the Schiff ba ...... e activation of the G protein.
@ast
Deprotonation of the Schiff ba ...... e activation of the G protein.
@en
P2860
P356
P1476
Deprotonation of the Schiff ba ...... he activation of the G protein
@en
P2093
R D Calhoon
P2860
P304
P356
10.1073/PNAS.83.12.4209
P407
P577
1986-06-01T00:00:00Z