Tumor-infiltrating lymphocytes genetically engineered with an inducible gene encoding interleukin-12 for the immunotherapy of metastatic melanoma
about
Producer T cells: Using genetically engineered T cells as vehicles to generate and deliver therapeutics to tumorsCAR models: next-generation CAR modifications for enhanced T-cell functionChimeric antigen receptor T-cell therapy for solid tumorsSynthetic biology approaches to engineer T cellsImproving Adoptive T Cell Therapy: The Particular Role of T Cell Costimulation, Cytokines, and Post-Transfer VaccinationTechnical Considerations for the Generation of Adoptively Transferred T Cells in Cancer ImmunotherapyPD-1 inhibition and treatment of advanced melanoma-role of pembrolizumabTaming immune suppressor: application of myeloid-derived suppressor cells in anti-cancer gene therapy.Driving CAR T-cells forwardA phase I clinical trial of adoptive T cell therapy using IL-12 secreting MUC-16(ecto) directed chimeric antigen receptors for recurrent ovarian cancer.Dihydrofolate Reductase and Thymidylate Synthase Transgenes Resistant to Methotrexate Interact to Permit Novel Transgene Regulation.CD8 engineered cytotoxic T cells reprogram melanoma tumor environment.Ameliorating the tumor microenvironment for antitumor responses through TLR5 ligand-secreting T cells.Enhancing adoptive T cell immunotherapy with microRNA therapeutics.Molecular Pathways: Breaking the Epithelial Cancer Barrier for Chimeric Antigen Receptor and T-cell Receptor Gene TherapyUtilizing cell-based therapeutics to overcome immune evasion in hematologic malignancies.Tumor-infiltrating lymphocytes predict prognosis of breast cancer patients treated with anti-Her-2 therapyGene therapy approaches against cancer using in vivo and ex vivo gene transfer of interleukin-12.In vitro exploration of a myeloid-derived suppressor cell line as vehicle for cancer gene therapy.Cancer Immunotherapy: Whence and Whither.Optimizing T-cell receptor gene therapy for hematologic malignancies.T-lymphocyte homing: an underappreciated yet critical hurdle for successful cancer immunotherapy.Enhancement of PSMA-Directed CAR Adoptive Immunotherapy by PD-1/PD-L1 Blockade.The Principles of Engineering Immune Cells to Treat Cancer.Development of CAR T cells designed to improve antitumor efficacy and safety.CARs: Synthetic Immunoreceptors for Cancer Therapy and Beyond.Increasing the safety and efficacy of chimeric antigen receptor T cell therapy.Adoptive T cell therapy: An overview of obstacles and opportunities.A Novel Method to Generate and Expand Clinical-Grade, Genetically Modified, Tumor-Infiltrating Lymphocytes.Armored CAR T cells enhance antitumor efficacy and overcome the tumor microenvironment.Preclinical validation: LV/IL-12 transduction of patient leukemia cells for immunotherapy of AML.Genetically Modified T-cell Therapy for the Treatment of Osteosarcoma: An Update.Transgenic Expression of IL15 Improves Antiglioma Activity of IL13Rα2-CAR T Cells but Results in Antigen Loss Variants.Constitutive Signaling from an Engineered IL7 Receptor Promotes Durable Tumor Elimination by Tumor-Redirected T Cells.Intra-tumoral production of IL18, but not IL12, by TCR-engineered T cells is non-toxic and counteracts immune evasion of solid tumors.A novel chimeric antigen receptor containing a JAK-STAT signaling domain mediates superior antitumor effects.Chimeric antigen receptor transduced T cells: Tuning up for the next generation.Augmentation of Antitumor Immunity by Human and Mouse CAR T Cells Secreting IL-18.Engineering chimeric antigen receptor-T cells for cancer treatment.PIM-2 protein kinase negatively regulates T cell responses in transplantation and tumor immunity.
P2860
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P2860
Tumor-infiltrating lymphocytes genetically engineered with an inducible gene encoding interleukin-12 for the immunotherapy of metastatic melanoma
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Tumor-infiltrating lymphocytes ...... therapy of metastatic melanoma
@ast
Tumor-infiltrating lymphocytes ...... therapy of metastatic melanoma
@en
type
label
Tumor-infiltrating lymphocytes ...... therapy of metastatic melanoma
@ast
Tumor-infiltrating lymphocytes ...... therapy of metastatic melanoma
@en
prefLabel
Tumor-infiltrating lymphocytes ...... therapy of metastatic melanoma
@ast
Tumor-infiltrating lymphocytes ...... therapy of metastatic melanoma
@en
P2093
P2860
P1476
Tumor-infiltrating lymphocytes ...... therapy of metastatic melanoma
@en
P2093
Azam V Nahvi
Giao Q Phan
James C Yang
Lien T Ngo
Ling Zhang
Mark E Dudley
Mary Ann Toomey
Marybeth S Hughes
Richard A Morgan
Richard M Sherry
P2860
P304
P356
10.1158/1078-0432.CCR-14-2085
P407
P577
2015-02-18T00:00:00Z