Beta-sheet core of human prion protein amyloid fibrils as determined by hydrogen/deuterium exchange
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Techniques to elucidate the conformation of prionsPrion Fibrillization Is Mediated by a Native Structural Element That Comprises Helices H2 and H3Unique Structural Characteristics of the Rabbit Prion ProteinSolution Structure and Dynamics of the I214V Mutant of the Rabbit Prion ProteinCrystal Structure of a Human Prion Protein Fragment Reveals a Motif for Oligomer FormationThe effect of β2-α2 loop mutation on amyloidogenic properties of the prion proteinIsolation of proteinase K-sensitive prions using pronase E and phosphotungstic acidCharge neutralization of the central lysine cluster in prion protein (PrP) promotes PrP(Sc)-like folding of recombinant PrP amyloids.Progress towards structural understanding of infectious sheep PrP-amyloid.Prion Protein Prolines 102 and 105 and the Surrounding Lysine Cluster Impede Amyloid Formation.A new approach to explore the impact of freeze-thaw cycling on protein structure: hydrogen/deuterium exchange mass spectrometry (HX-MS).Post-translational modifications in PrP expand the conformational diversity of prions in vivoGlobular domain of the prion protein needs to be unlocked by domain swapping to support prion protein conversionConformational stability of PrP amyloid fibrils controls their smallest possible fragment size.Getting a grip on prions: oligomers, amyloids, and pathological membrane interactions.How amide hydrogens exchange in native proteinsNanomechanical properties of human prion protein amyloid as probed by force spectroscopy.Methionine sulfoxides on prion protein Helix-3 switch on the alpha-fold destabilization required for conversion.Prion diseases and their biochemical mechanisms.Structural characterization of semen coagulum-derived SEM1(86-107) amyloid fibrils that enhance HIV-1 infection.Probing the conformation of a prion protein fibril with hydrogen exchange.The α-helical C-terminal domain of full-length recombinant PrP converts to an in-register parallel β-sheet structure in PrP fibrils: evidence from solid state nuclear magnetic resonance.Influence of pH on the human prion protein: insights into the early steps of misfolding.The intrinsic helical propensities of the helical fragments in prion protein under neutral and low pH conditions: a replica exchange molecular dynamics study.Elongation of mouse prion protein amyloid-like fibrils: effect of temperature and denaturant concentration.Microsecond unfolding kinetics of sheep prion protein reveals an intermediate that correlates with susceptibility to classical scrapie.Disulfide mapping reveals the domain swapping as the crucial process of the structural conversion of prion proteinPrP assemblies: spotting the responsible regions in prion propagation.Fibril formation of the rabbit/human/bovine prion proteinsInteraction of prion protein with acetylcholinesterase: potential pathobiological implications in prion diseases.Solid-state NMR studies of amyloid fibril structureStructural determinants of phenotypic diversity and replication rate of human prions.Comparative analysis of essential collective dynamics and NMR-derived flexibility profiles in evolutionarily diverse prion proteinsStructural polymorphism in amyloids: new insights from studies with Y145Stop prion protein fibrils.A Structural and Functional Comparison Between Infectious and Non-Infectious Autocatalytic Recombinant PrP Conformers.Non-reducing alkaline solubilization and rapid on-column refolding of recombinant prion protein.Integrity of helix 2-helix 3 domain of the PrP protein is not mandatory for prion replication.Structural organization of brain-derived mammalian prions examined by hydrogen-deuterium exchange.Dissociation of recombinant prion protein fibrils into short protofilaments: implications for the endocytic pathway and involvement of the N-terminal domain.Computer simulation study of amyloid fibril formation by palindromic sequences in prion peptides
P2860
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P2860
Beta-sheet core of human prion protein amyloid fibrils as determined by hydrogen/deuterium exchange
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Beta-sheet core of human prion ...... by hydrogen/deuterium exchange
@ast
Beta-sheet core of human prion ...... by hydrogen/deuterium exchange
@en
type
label
Beta-sheet core of human prion ...... by hydrogen/deuterium exchange
@ast
Beta-sheet core of human prion ...... by hydrogen/deuterium exchange
@en
prefLabel
Beta-sheet core of human prion ...... by hydrogen/deuterium exchange
@ast
Beta-sheet core of human prion ...... by hydrogen/deuterium exchange
@en
P2860
P356
P1476
Beta-sheet core of human prion ...... by hydrogen/deuterium exchange
@en
P2093
Patrick L Wintrode
Witold K Surewicz
P2860
P304
P356
10.1073/PNAS.0608447104
P407
P50
P577
2007-01-22T00:00:00Z