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Beta-sheet core of human prion protein amyloid fibrils as determined by hydrogen/deuterium exchangeInhibition of CD73 AMP hydrolysis by a therapeutic antibody with a dual, non-competitive mechanism of action.Distinct structures of scrapie prion protein (PrPSc)-seeded versus spontaneous recombinant prion protein fibrils revealed by hydrogen/deuterium exchange.Rapid assessment of oxidation via middle-down LCMS correlates with methionine side-chain solvent-accessible surface area for 121 clinical stage monoclonal antibodies.Linear epitope mapping by native mass spectrometry.An "Fc-Silenced" IgG1 Format With Extended Half-Life Designed for Improved Stability.Elucidation of PEGylation site with a combined approach of in-source fragmentation and CID MS/MSInterlaboratory Comparison of Hydrogen-Deuterium Exchange Mass Spectrometry Measurements of the Fab Fragment of NISTmAb
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description
researcher ORCID ID = 0000-0001-5251-4343
@en
wetenschapper
@nl
name
Xiaojun Lu
@ast
Xiaojun Lu
@en
Xiaojun Lu
@nl
type
label
Xiaojun Lu
@ast
Xiaojun Lu
@en
Xiaojun Lu
@nl
prefLabel
Xiaojun Lu
@ast
Xiaojun Lu
@en
Xiaojun Lu
@nl
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P496
0000-0001-5251-4343