The ABCs of drug transport in intestine and liver: efflux proteins limiting drug absorption and bioavailability.
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Plasma membrane transporters in modern liver pharmacologyDevelopmental pharmacokinetics in pediatric populationsPotential pharmacokinetic interactions between antiretrovirals and medicinal plants used as complementary and African traditional medicinesSimultaneous measurement of in vivo P-glycoprotein and cytochrome P450 3A activitiesRegulation of biotransformation systems and ABC transporters by benznidazole in HepG2 cells: involvement of pregnane X-receptorAge-related P-glycoprotein expression in the intestine and affecting the pharmacokinetics of orally administered enrofloxacin in broilersIntestinal and hepatic expression of cytochrome P450s and mdr1a in rats with indomethacin-induced small intestinal ulcersIntestinal fluid volumes and transit of dosage forms as assessed by magnetic resonance imaging.Recent advances in pharmacokinetic extrapolation from preclinical data to humans.Multiple drugbinding sites on the R482G isoform of the ABCG2 transporter.Human growth hormone-transferrin fusion protein for oral delivery in hypophysectomized rats.Effects of resveratrol on drug- and carcinogen-metabolizing enzymes, implications for cancer prevention.Effect of drug transporter genotypes on pravastatin disposition in European- and African-American participantsEnteroaggregative Escherichia coli promotes transepithelial migration of neutrophils through a conserved 12-lipoxygenase pathway.Diurnal rhythmicity in the transcription of jejunal drug transporters.P-Glycoprotein- and cytochrome P-450-mediated herbal drug interactions.Overcoming drug resistance by regulating nuclear receptors.Structure, function, expression, genomic organization, and single nucleotide polymorphisms of human ABCB1 (MDR1), ABCC (MRP), and ABCG2 (BCRP) efflux transporters.Nanomedicine in GIPharmacogenetics of OATP (SLC21/SLCO), OAT and OCT (SLC22) and PEPT (SLC15) transporters in the intestine, liver and kidney.Upregulation of P-glycoprotein by probiotics in intestinal epithelial cells and in the dextran sulfate sodium model of colitis in mice.PharmGKB summary: methotrexate pathway.Systems pharmacology dissection of the anti-inflammatory mechanism for the medicinal herb Folium eriobotryae.Application of Caco-2 cell line in herb-drug interaction studies: current approaches and challengesClinical implications of changes in hepatic drug metabolism in older peopleDose-dependent disposition of methotrexate in Abcc2 and Abcc3 gene knockout murine models.The ABC transporters MDR1 and MRP2: multiple functions in disposition of xenobiotics and drug resistance.Strategies to improve oral drug bioavailability.A systems biology approach to understanding the mechanisms of action of chinese herbs for treatment of cardiovascular disease.Structure and function of the MRP2 (ABCC2) protein and its role in drug disposition.Active transport across the human placenta: impact on drug efficacy and toxicity.Scheduling of anticancer drugs: timing may be everything.Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs.Natural polyphenol disposition via coupled metabolic pathways.Application of receiver operating characteristic analysis to refine the prediction of potential digoxin drug interactions.Antiretroviral drug transporters and metabolic enzymes in human testicular tissue: potential contribution to HIV-1 sanctuary site.Transporter-mediated uptake into cellular compartments.Multidrug resistance-associated transporter 2 regulates mucosal inflammation by facilitating the synthesis of hepoxilin A3.Overlapping functions of ABC transporters in topotecan disposition as determined in gene knockout mouse models.Reversal of ABC drug transporter-mediated multidrug resistance in cancer cells: evaluation of current strategies.
P2860
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P2860
The ABCs of drug transport in intestine and liver: efflux proteins limiting drug absorption and bioavailability.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
The ABCs of drug transport in ...... bsorption and bioavailability.
@ast
The ABCs of drug transport in ...... bsorption and bioavailability.
@en
type
label
The ABCs of drug transport in ...... bsorption and bioavailability.
@ast
The ABCs of drug transport in ...... bsorption and bioavailability.
@en
prefLabel
The ABCs of drug transport in ...... bsorption and bioavailability.
@ast
The ABCs of drug transport in ...... bsorption and bioavailability.
@en
P2093
P1476
The ABCs of drug transport in ...... bsorption and bioavailability.
@en
P2093
Barry H Hirst
Lauretta M S Chan
Simon Lowes
P356
10.1016/J.EJPS.2003.07.003
P407
P577
2004-01-01T00:00:00Z