Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs. - Wikidata - wikimedia - TriplyDB

Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs.

Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs.

http://www.wikidata.org/entity/Q36748145

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Anaphylactic reactions to oligosaccharides in red meat: a syndrome in evolution.Controlled release systems containing solid dispersions: strategies and mechanisms Nanostructured lipid carriers: An emerging platform for improving oral bioavailability of lipophilic drugs Models for Predicting Drug Absorption From Oral Lipid-Based Formulations Emerging research and clinical development trends of liposome and lipid nanoparticle drug delivery systems Direct visualization of dispersed lipid bicontinuous cubic phases by cryo-electron tomography.Food-associated stimuli enhance barrier properties of gastrointestinal mucus DLL4 promotes continuous adult intestinal lacteal regeneration and dietary fat transport.Emulsified phosphatidylserine, simple and effective peptide carrier for induction of potent epitope-specific T cell responses Intravital imaging of intestinal lacteals unveils lipid drainage through contractility Liposomal delivery systems for intestinal lymphatic drug transport Pharmacokinetic aspects and in vitro-in vivo correlation potential for lipid-based formulations A new strategy for enhancing the oral bioavailability of drugs with poor water-solubility and low liposolubility based on phospholipid complex and supersaturated SEDDS Release of a Poorly Soluble Drug from Hydrophobically Modified Poly (Acrylic Acid) in Simulated Intestinal Fluids Liquid proliposomes of nimodipine drug delivery system: preparation, characterization, and pharmacokinetics Modulating Drug Release and Enhancing the Oral Bioavailability of Torcetrapib with Solid Lipid Dispersion Formulations.Downscaling drug nanosuspension production: processing aspects and physicochemical characterization.A simple quantitative approach for the determination of long and medium chain lipids in bio-relevant matrices by high performance liquid chromatography with refractive index detection.The visualisation and quantification of human gastrointestinal fat distribution with MRI: a randomised study in healthy subjects.Sensing of dietary lipids by enterocytes: a new role for SR-BI/CLA-1 Formulation and evaluation of matrix type mucoadhesive tablets aimed at treating oral aphtha.Critical concentrations in the dilution of oral self-microemulsifying drug delivery systems.Porous magnesium aluminometasilicate tablets as carrier of a cyclosporine self-emulsifying formulation.Glyceryl monooleate/poloxamer 407 cubic nanoparticles as oral drug delivery systems: I. In vitro evaluation and enhanced oral bioavailability of the poorly water-soluble drug simvastatin.Development of solid lipid nanoparticles containing total flavonoid extract from Dracocephalum moldavica L. and their therapeutic effect against myocardial ischemia-reperfusion injury in rats.Pharmacokinetics and enhanced oral bioavailability in beagle dogs of cyclosporine A encapsulated in glyceryl monooleate/poloxamer 407 cubic nanoparticles Self-microemulsifying drug delivery system for improving the bioavailability of huperzine A by lymphatic uptake.Improving In Vivo Efficacy of Bioactive Molecules: An Overview of Potentially Antitumor Phytochemicals and Currently Available Lipid-Based Delivery Systems.The role of calcium in membrane condensation and spontaneous curvature variations in model lipidic systems.Epigenetic and antitumor effects of platinum(IV)-octanoato conjugates.Absorption enhancement of adefovir dipivoxil by incorporating MCT and ethyl oleate complex oil phase in emulsion.Proliposomes for oral delivery of dehydrosilymarin: preparation and evaluation in vitro and in vivo.Enhanced oral absorption and therapeutic effect of acetylpuerarin based on D-α-tocopheryl polyethylene glycol 1000 succinate nanoemulsions.The use of biorelevant dissolution media to forecast the in vivo performance of a drug.Revisiting the rule of five on the basis of pharmacokinetic data from rat.Silymarin glyceryl monooleate/poloxamer 407 liquid crystalline matrices: physical characterization and enhanced oral bioavailability.A mouse model to evaluate the impact of species, sex, and lipid load on lymphatic drug transport The preparation and evaluation of self-nanoemulsifying systems containing Swietenia oil and an examination of its anti-inflammatory effects Drug structure-transport relationships Effects of PEGylated lipid nanoparticles on the oral absorption of one BCS II drug: a mechanistic investigation

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P2860

Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs.

http://www.wikidata.org/entity/Q36748145

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Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs.

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Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs.

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Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs.

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Nature Reviews Drug Discovery

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Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs.

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Christopher J H Porter

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Natalie L Trevaskis

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William N Charman

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P2860

Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters

Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease

CD36 deficiency impairs intestinal lipid secretion and clearance of chylomicrons from the blood

Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor beta(delta)

VIP21/caveolin is a cholesterol-binding protein

A selective peroxisome proliferator-activated receptor delta agonist promotes reverse cholesterol transport

Apical sodium dependent bile acid transporter (ASBT, SLC10A2): a potential prodrug target

Mechanisms of digestion and absorption of dietary vitamin A.

Sterol carrier protein-2

Identification of the major intestinal fatty acid transport protein

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231-248

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10.1038/NRD2197

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