Selective inhibition of the MCP-1-CCR2 ligand-receptor axis decreases systemic trafficking of macrophages in the presence of UHMWPE particles
about
The future of biologic coatings for orthopaedic implantsThe pathobiology and pathology of aseptic implant failureThe pathology of orthopedic implant failure is mediated by innate immune system cytokines.Mutant monocyte chemoattractant protein 1 protein attenuates migration of and inflammatory cytokine release by macrophages exposed to orthopedic implant wear particles.Local effect of IL-4 delivery on polyethylene particle induced osteolysis in the murine calvarium.Interaction of Materials and Biology in Total Joint Replacement - Successes, Challenges and Future Directions.Modulation of mouse macrophage polarization in vitro using IL-4 delivery by osmotic pumps.Establishment of Green Fluorescent Protein and Firefly Luciferase Expressing Mouse Primary Macrophages for In Vivo Bioluminescence Imaging.Effect of a CCR1 receptor antagonist on systemic trafficking of MSCs and polyethylene particle-associated bone loss.Immune modulation as a therapeutic strategy in bone regeneration.The role of MCP-1-CCR2 ligand-receptor axis in chondrocyte degradation and disease progress in knee osteoarthritis.Exogenous MC3T3 preosteoblasts migrate systemically and mitigate the adverse effects of wear particlesLocal delivery of mutant CCL2 protein-reduced orthopaedic implant wear particle-induced osteolysis and inflammation in vivoInflammation, fracture and bone repair.Revision joint replacement, wear particles, and macrophage polarization.Macrophages-Key cells in the response to wear debris from joint replacements.Chemokines Associated with Pathologic Responses to Orthopedic Implant Debris.Osteolysis around total knee arthroplasty: a review of pathogenetic mechanisms.The role of TLR and chemokine in wear particle-induced aseptic loosening.Novel biological strategies for treatment of wear particle-induced periprosthetic osteolysis of orthopaedic implants for joint replacement.Orthopaedic implant failure: aseptic implant loosening--the contribution and future challenges of mouse models in translational research.The biological response to orthopedic implants for joint replacement. II: Polyethylene, ceramics, PMMA, and the foreign body reaction.Dendritic cells enhance UHMWPE wear particle-induced osteoclast differentiation of macrophages.Gene Expression in Osteolysis: Review on the Identification of Altered Molecular Pathways in Preclinical and Clinical Studies.Macrophage Migration Inhibitory Factor (MIF) Supports Homing of Osteoclast Precursors to Peripheral Osteolytic Lesions.The effect of local IL-4 delivery or CCL2 blockade on implant fixation and bone structural properties in a mouse model of wear particle induced osteolysis.The Role of the Chemokine System in Tissue Response to Prosthetic By-products Leading to Periprosthetic Osteolysis and Aseptic Loosening.Immunological Responses to Total Hip Arthroplasty.Role of macrophages in the biological reaction to wear debris from joint replacements.Strontium-Substituted Bioceramics Particles: A New Way to Modulate MCP-1 and Gro-α Production by Human Primary Osteoblastic CellsMacrophage polarization and activation in response to implant debris: influence by "particle disease" and "ion disease"Optimized dosing of a CCR2 antagonist for amplification of vaccine immunity.* Murine Model of Progressive Orthopedic Wear Particle-Induced Chronic Inflammation and Osteolysis.Mutant CCL2 protein coating mitigates wear particle-induced bone loss in a murine continuous polyethylene infusion model.Particle disease really does exist.
P2860
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P2860
Selective inhibition of the MCP-1-CCR2 ligand-receptor axis decreases systemic trafficking of macrophages in the presence of UHMWPE particles
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Selective inhibition of the MC ...... e presence of UHMWPE particles
@ast
Selective inhibition of the MC ...... e presence of UHMWPE particles
@en
type
label
Selective inhibition of the MC ...... e presence of UHMWPE particles
@ast
Selective inhibition of the MC ...... e presence of UHMWPE particles
@en
prefLabel
Selective inhibition of the MC ...... e presence of UHMWPE particles
@ast
Selective inhibition of the MC ...... e presence of UHMWPE particles
@en
P2093
P2860
P356
P1476
Selective inhibition of the MC ...... e presence of UHMWPE particles
@en
P2093
Emmanuel Gibon
Kate Fritton
Lane Smith
Pei-Gen Ren
Sandip Biswal
Stuart B Goodman
Zhenyu Yao
P2860
P304
P356
10.1002/JOR.21548
P577
2011-09-12T00:00:00Z