An antagonist of monocyte chemoattractant protein 1 (MCP-1) inhibits arthritis in the MRL-lpr mouse model
about
Role of the first extracellular loop in the functional activation of CCR2. The first extracellular loop contains distinct domains necessary for both agonist binding and transmembrane signalingDifferential activation of CC chemokine receptors by AOP-RANTESIdentification of the binding site for a novel class of CCR2b chemokine receptor antagonists: binding to a common chemokine receptor motif within the helical bundleBlasts from the pastCCR2 deficiency promotes exacerbated chronic erosive neutrophil-dominated chikungunya virus arthritisSynovial stromal cells from rheumatoid arthritis patients attract monocytes by producing MCP-1 and IL-8Chemokine blockade: a new era in the treatment of rheumatoid arthritis?Differential binding of chemokines to macrophages and neutrophils in the human inflamed synoviumEffect of a small molecule inhibitor of nuclear factor-kappaB nuclear translocation in a murine model of arthritis and cultured human synovial cellsLevels of gastrin-releasing peptide and substance P in synovial fluid and serum correlate with levels of cytokines in rheumatoid arthritis.T Cell Migration in Rheumatoid ArthritisNeutralization of Gro alpha and macrophage inflammatory protein-2 attenuates renal ischemia/reperfusion injuryBlocking of monocyte chemoattractant protein-1 during tubulointerstitial nephritis resulted in delayed neutrophil clearanceSevere reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2.The chemokine KC, but not monocyte chemoattractant protein-1, triggers monocyte arrest on early atherosclerotic endothelium.Chemokines: extracellular messengers for all occasions?The central and multiple roles of B cells in lupus pathogenesis.Global gene expression profile progression in Gaucher disease mouse modelsEnzyme degradation and proinflammatory activity in arthritogenic and nonarthritogenic Eubacterium aerofaciens cell wallsChemokines and chemokine receptors in arthritis.New therapies in development for autoimmune diseases: their rationale for combination treatment.The CCL2/CCR2 axis enhances vascular cell adhesion molecule-1 expression in human synovial fibroblastsBlood monocyte chemotactic protein-1 (MCP-1) and adapted disease activity Score28-MCP-1: favorable indicators for rheumatoid arthritis activity.CXCL16-mediated cell recruitment to rheumatoid arthritis synovial tissue and murine lymph nodes is dependent upon the MAPK pathwayNew therapeutics that modulate chemokine networks.Angiogenesis and chemokines in rheumatoid arthritis and other systemic inflammatory rheumatic diseases.Slit proteins, potential endogenous modulators of inflammation.Targeting monocyte chemoattractant protein-1 signalling in disease.The CC chemokine ligand, CCL2/MCP1, participates in macrophage fusion and foreign body giant cell formation.C-C chemokine-encoding DNA vaccines enhance breakdown of tolerance to their gene products and treat ongoing adjuvant arthritisChemokine and chemokine receptor structure and interactions: implications for therapeutic strategies.Chemokines in joint disease: the key to inflammation?Discovery, optimization, and pharmacological characterization of novel heteroaroylphenylureas antagonists of C-C chemokine ligand 2 functionIdentification of arthritis-related gene clusters by microarray analysis of two independent mouse models for rheumatoid arthritis.Selective inhibition of the MCP-1-CCR2 ligand-receptor axis decreases systemic trafficking of macrophages in the presence of UHMWPE particlesDifferential effect of methotrexate on the increased CCR2 density on circulating CD4 T lymphocytes and monocytes in active chronic rheumatoid arthritis, with a down regulation only on monocytes in respondersDual targeting of the chemokine receptors CXCR4 and ACKR3 with novel engineered chemokines.Increased expression of monocyte chemotactic protein-1 during active hepatic fibrogenesis: correlation with monocyte infiltration.CCR2 is required for CD8-induced graft-versus-host disease.Proteomic analysis of secreted proteins in early rheumatoid arthritis: anti-citrulline autoreactivity is associated with up regulation of proinflammatory cytokines
P2860
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P2860
An antagonist of monocyte chemoattractant protein 1 (MCP-1) inhibits arthritis in the MRL-lpr mouse model
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
An antagonist of monocyte chem ...... tis in the MRL-lpr mouse model
@ast
An antagonist of monocyte chem ...... tis in the MRL-lpr mouse model
@en
type
label
An antagonist of monocyte chem ...... tis in the MRL-lpr mouse model
@ast
An antagonist of monocyte chem ...... tis in the MRL-lpr mouse model
@en
prefLabel
An antagonist of monocyte chem ...... tis in the MRL-lpr mouse model
@ast
An antagonist of monocyte chem ...... tis in the MRL-lpr mouse model
@en
P2093
P2860
P356
P1476
An antagonist of monocyte chem ...... tis in the MRL-lpr mouse model
@en
P2093
I Clark-Lewis
J D Waterfield
L G Ratkay
P2860
P304
P356
10.1084/JEM.186.1.131
P407
P577
1997-07-01T00:00:00Z