The WD40 repeat protein WDR26 binds Gβγ and promotes Gβγ-dependent signal transduction and leukocyte migration
about
PLEKHG2 promotes heterotrimeric G protein βγ-stimulated lymphocyte migration via Rac and Cdc42 activation and actin polymerization.Immunomodulatory effects mediated by serotoninWDR26 is a new partner of Axin1 in the canonical Wnt signaling pathwayDefective chemokine signal integration in leukocytes lacking activator of G protein signaling 3 (AGS3)RIP1 Cleavage in the Kinase Domain Regulates TRAIL-Induced NF-κB Activation and Lymphoma Survival.Characterization of Novel Molecular Mechanisms Favoring Rac1 Membrane Translocation.WDR26 functions as a scaffolding protein to promote Gβγ-mediated phospholipase C β2 (PLCβ2) activation in leukocytes.Upregulated WDR26 serves as a scaffold to coordinate PI3K/ AKT pathway-driven breast cancer cell growth, migration, and invasion.The Gβ3 splice variant associated with the C825T gene polymorphism is an unstable and functionally inactive proteinWD40-repeat proteins control the flow of Gβγ signaling for directional cell migration.WDR26 promotes mitophagy of cardiomyocytes induced by hypoxia through Parkin translocation.WDR26 Haploinsufficiency Causes a Recognizable Syndrome of Intellectual Disability, Seizures, Abnormal Gait, and Distinctive Facial Features.Refinement of the critical region of 1q41q42 microdeletion syndrome identifies FBXO28 as a candidate causative gene for intellectual disability and seizures.A novel long noncoding RNA lncWDR26 suppresses the growth and metastasis of hepatocellular carcinoma cells through interaction with SIX3.
P2860
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P2860
The WD40 repeat protein WDR26 binds Gβγ and promotes Gβγ-dependent signal transduction and leukocyte migration
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
The WD40 repeat protein WDR26 ...... uction and leukocyte migration
@ast
The WD40 repeat protein WDR26 ...... uction and leukocyte migration
@en
type
label
The WD40 repeat protein WDR26 ...... uction and leukocyte migration
@ast
The WD40 repeat protein WDR26 ...... uction and leukocyte migration
@en
prefLabel
The WD40 repeat protein WDR26 ...... uction and leukocyte migration
@ast
The WD40 repeat protein WDR26 ...... uction and leukocyte migration
@en
P2093
P2860
P356
P1476
The WD40 repeat protein WDR26 ...... uction and leukocyte migration
@en
P2093
Songhai Chen
Xiaoyun Tang
Zhizeng Sun
P2860
P304
43902-43912
P356
10.1074/JBC.M111.301382
P407
P577
2011-11-07T00:00:00Z