Mice deficient in the ALS2 gene exhibit lymphopenia and abnormal hematopietic function.

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Redox modifier genes and pathways in amyotrophic lateral sclerosis.Alsin and the molecular pathways of amyotrophic lateral sclerosis Amyotrophic lateral sclerosis: applications of stem cells - an update.

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Mice deficient in the ALS2 gene exhibit lymphopenia and abnormal hematopietic function.

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2006 nî lūn-bûn

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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2006年论文

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2006年论文

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name

Mice deficient in the ALS2 gene exhibit lymphopenia and abnormal hematopietic function.

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Mice deficient in the ALS2 gene exhibit lymphopenia and abnormal hematopietic function.

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type

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Mice deficient in the ALS2 gene exhibit lymphopenia and abnormal hematopietic function.

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Mice deficient in the ALS2 gene exhibit lymphopenia and abnormal hematopietic function.

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Mice deficient in the ALS2 gene exhibit lymphopenia and abnormal hematopietic function.

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Mice deficient in the ALS2 gene exhibit lymphopenia and abnormal hematopietic function.

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P1476

Mice deficient in the ALS2 gene exhibit lymphopenia and abnormal hematopietic function

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P2093

Aleah L Smith

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Chengsong Xie

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Elizabeth A Erie

http://www.w3.org/2001/XMLSchema#string

Hoon Shim

http://www.w3.org/2001/XMLSchema#string

Jichun Chen

http://www.w3.org/2001/XMLSchema#string

Keyvan Keyvanfar

http://www.w3.org/2001/XMLSchema#string

Xian Lin

http://www.w3.org/2001/XMLSchema#string

P2860

A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2

ALS2, a novel guanine nucleotide exchange factor for the small GTPase Rab5, is implicated in endosomal dynamics

Unstable mutants in the peripheral endosomal membrane component ALS2 cause early-onset motor neuron disease

Dominant negative mutation of the hematopoietic-specific Rho GTPase, Rac2, is associated with a human phagocyte immunodeficiency

The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis

From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS

Mice deficient in the Rab5 guanine nucleotide exchange factor ALS2/alsin exhibit age-dependent neurological deficits and altered endosome trafficking

Alsin is a Rab5 and Rac1 guanine nucleotide exchange factor

Als2-deficient mice exhibit disturbances in endosome trafficking associated with motor behavioral abnormalities

Loss of ALS2 function is insufficient to trigger motor neuron degeneration in knock-out mice but predisposes neurons to oxidative stress

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226-231

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scholarly article

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10.1016/J.JNEUROIM.2006.10.019

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1-2

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182

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Huaibin Cai

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2006-12-06T00:00:00Z

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1796843

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Mice deficient in the ALS2 gene exhibit lymphopenia and abnormal hematopietic function.

about

P2860

P2860

Mice deficient in the ALS2 gene exhibit lymphopenia and abnormal hematopietic function.

description

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P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P5875

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P5875

P698

P932