A study of iterative type II polyketide synthases, using bacterial genes cloned from soil DNA: a means to access and use genes from uncultured microorganisms.
about
Acylation of Biomolecules in Prokaryotes: a Widespread Strategy for the Control of Biological Function and Metabolic StressInsight into the Molecular Basis of Aromatic Polyketide Cyclization: Crystal Structure and in Vitro Characterization of WhiE-ORFVIIdentification of unique type II polyketide synthase genes in soilStrategies for discovery and improvement of enzyme function: state of the art and opportunitiesMetagenomics: Future of microbial gene miningMetagenomics: application of genomics to uncultured microorganismsConstruction of environmental DNA libraries in Escherichia coli and screening for the presence of genes conferring utilization of 4-hydroxybutyrateRecombinant environmental libraries provide access to microbial diversity for drug discovery from natural products.Screening of environmental DNA libraries for the presence of genes conferring lipolytic activity on Escherichia coli.Cloning the soil metagenome: a strategy for accessing the genetic and functional diversity of uncultured microorganismsCharacterization of a forest soil metagenome clone that confers indirubin and indigo production on Escherichia coliEnvironmental whole-genome amplification to access microbial populations in contaminated sediments.Forest soil metagenome gene cluster involved in antifungal activity expression in Escherichia coli.Marine metagenomics: strategies for the discovery of novel enzymes with biotechnological applications from marine environments.Functional characterization of a new holin-like antibacterial protein coding gene tmp1 from goat skin surface metagenome.Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural productsFunctional analysis of environmental DNA-derived type II polyketide synthases reveals structurally diverse secondary metabolites.Genes for production of the enediyne antitumor antibiotic C-1027 in Streptomyces globisporus are clustered with the cagA gene that encodes the C-1027 apoprotein.DNA from uncultured organisms as a source of 2,5-diketo-D-gluconic acid reductasesGene cassette PCR: sequence-independent recovery of entire genes from environmental DNA.Biosynthesis of polyketides in heterologous hostsMetagenomic analysis of Streptomyces lividans reveals host-dependent functional expression.Mining the metabiome: identifying novel natural products from microbial communities.Platforms for antibiotic discovery.mRNA differential display in a microbial enrichment culture: simultaneous identification of three cyclohexanone monooxygenases from three speciesArimetamycin A: improving clinically relevant families of natural products through sequence-guided screening of soil metagenomes.Mining soil metagenomes to better understand the evolution of natural product structural diversity: pentangular polyphenols as a case study.Using natural products for drug discovery: the impact of the genomics era.Functional analysis of environmental DNA-derived microviridins provides new insights into the diversity of the tricyclic peptide family.Metagenomic approaches to natural products from free-living and symbiotic organisms.Culture-independent discovery of natural products from soil metagenomes.Genomic and functional techniques to mine the microbiome for novel antimicrobials and antimicrobial resistance genes.Use of direct-infusion electrospray mass spectrometry to guide empirical development of improved conditions for expression of secondary metabolites from actinomycetes.Bacterial diversity in maize rhizospheres: conclusions on the use of genetic profiles based on PCR-amplified partial small subunit rRNA genes in ecological studies.Genetically modified bacterial strains and novel bacterial artificial chromosome shuttle vectors for constructing environmental libraries and detecting heterologous natural products in multiple expression hosts.Arixanthomycins A-C: Phylogeny-guided discovery of biologically active eDNA-derived pentangular polyphenolsAcetoacetyl-CoA synthetase activity is controlled by a protein acetyltransferase with unique domain organization in Streptomyces lividans.Cloning large natural product gene clusters from the environment: piecing environmental DNA gene clusters back together with TAR.An environmental DNA-derived type II polyketide biosynthetic pathway encodes the biosynthesis of the pentacyclic polyketide erdacin.Fluostatins produced by the heterologous expression of a TAR reassembled environmental DNA derived type II PKS gene cluster.
P2860
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P2860
A study of iterative type II polyketide synthases, using bacterial genes cloned from soil DNA: a means to access and use genes from uncultured microorganisms.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
A study of iterative type II p ...... rom uncultured microorganisms.
@ast
A study of iterative type II p ...... rom uncultured microorganisms.
@en
type
label
A study of iterative type II p ...... rom uncultured microorganisms.
@ast
A study of iterative type II p ...... rom uncultured microorganisms.
@en
prefLabel
A study of iterative type II p ...... rom uncultured microorganisms.
@ast
A study of iterative type II p ...... rom uncultured microorganisms.
@en
P2093
P2860
P1476
A study of iterative type II p ...... rom uncultured microorganisms.
@en
P2093
C R Hutchinson
E Wendt-Pienkowski
P2860
P304
P356
10.1128/JB.179.23.7360-7368.1997
P407
P577
1997-12-01T00:00:00Z