Metagenomic approaches to natural products from free-living and symbiotic organisms.
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Insights into novel antimicrobial compounds and antibiotic resistance genes from soil metagenomesAsteropsin A: An unusual cystine-crosslinked peptide from porifera enhances neuronal Ca2+ influxThe discovery of new cyanobactins from Cyanothece PCC 7425 defines a new signature for processing of patellamidesHybrid sequencing approach applied to human fecal metagenomic clone libraries revealed clones with potential biotechnological applicationsDissecting metabolic puzzles through isotope feeding: a novel amino acid in the biosynthetic pathway of the cruciferous phytoalexins rapalexin A and isocyalexin A.Identifying active phage lysins through functional viral metagenomics.Current approaches to exploit actinomycetes as a source of novel natural products.Marine genomics: at the interface of marine microbial ecology and biodiscoveryEmerging strategies and integrated systems microbiology technologies for biodiscovery of marine bioactive compounds.Polyketide synthase pathways identified from a metagenomic library are derived from soil Acidobacteria.Functional analysis of environmental DNA-derived type II polyketide synthases reveals structurally diverse secondary metabolites.Long-chain N-acyl amino acid synthases are linked to the putative PEP-CTERM/exosortase protein-sorting system in Gram-negative bacteriaDiversity and antimicrobial activities of microbes from two Irish marine sponges, Suberites carnosus and Leucosolenia sp.Environmental DNA-encoded antibiotics fasamycins A and B inhibit FabF in type II fatty acid biosynthesisPorphyrins from a metagenomic library of the marine sponge Discodermia calyx.Natural products: a continuing source of novel drug leadsWhat we can learn from sushi: a review on seaweed-bacterial associations.An environmental bacterial taxon with a large and distinct metabolic repertoire.Selective enrichment of environmental DNA libraries for genes encoding nonribosomal peptides and polyketides by phosphopantetheine transferase-dependent complementation of siderophore biosynthesis.Reassembly of functionally intact environmental DNA-derived biosynthetic gene clustersDeep sequencing of non-ribosomal peptide synthetases and polyketide synthases from the microbiomes of Australian marine sponges.Meta-omic characterization of prokaryotic gene clusters for natural product biosynthesis.Marine actinobacteria associated with marine organisms and their potentials in producing pharmaceutical natural products.Bacterial symbionts and natural products.Functional metagenomic discovery of bacterial effectors in the human microbiome and isolation of commendamide, a GPCR G2A/132 agonistLinking Biosynthetic Gene Clusters to their Metabolites via Pathway- Targeted Molecular Networking.Lichens as natural sources of biotechnologically relevant bacteria.Dung-inhabiting fungi: a potential reservoir of novel secondary metabolites for the control of plant pathogens.Microbial strain prioritization using metabolomics tools for the discovery of natural products.Microbial genome mining answers longstanding biosynthetic questions.Natural product discovery from the human microbiome.Metabolic profiling as a tool for prioritizing antimicrobial compoundsHarnessing natural product assembly lines: structure, promiscuity, and engineering.Functional analysis of environmental DNA-derived microviridins provides new insights into the diversity of the tricyclic peptide family.Merging chemical ecology with bacterial genome mining for secondary metabolite discoveryNatural products and Chagas' disease: a review of plant compounds studied for activity against Trypanosoma cruzi.Prospects for new antibiotics: a molecule-centered perspective.Indole Derivatives Produced by the Metagenome Genes of the Escherichia coli-Harboring Marine Sponge Discodermia calyx.Coping with antibiotic resistance: contributions from genomics.Antibiotics and specialized metabolites from the human microbiota.
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P2860
Metagenomic approaches to natural products from free-living and symbiotic organisms.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 16 September 2009
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vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Metagenomic approaches to natural products from free-living and symbiotic organisms.
@en
Metagenomic approaches to natural products from free-living and symbiotic organisms.
@nl
type
label
Metagenomic approaches to natural products from free-living and symbiotic organisms.
@en
Metagenomic approaches to natural products from free-living and symbiotic organisms.
@nl
prefLabel
Metagenomic approaches to natural products from free-living and symbiotic organisms.
@en
Metagenomic approaches to natural products from free-living and symbiotic organisms.
@nl
P2093
P2860
P356
P1476
Metagenomic approaches to natural products from free-living and symbiotic organisms.
@en
P2093
Eric W Schmidt
Jeffrey H Kim
Luke Simmons
Sean F Brady
P2860
P304
P356
10.1039/B817078A
P577
2009-09-16T00:00:00Z