Cyclic strain induces dual-mode endothelial-mesenchymal transformation of the cardiac valve.
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Endothelial Plasticity: Shifting Phenotypes through Force FeedbackMitral valve disease--morphology and mechanisms.Conserved transcriptional regulatory mechanisms in aortic valve development and diseaseIn vitro models of aortic valve calcification: solidifying a systemMolecular and cellular aspects of calcific aortic valve diseaseThe role of mechanotransduction on vascular smooth muscle myocytes' [corrected] cytoskeleton and contractile functionMatrix production and organization by endothelial colony forming cells in mechanically strained engineered tissue constructsAccelerating drug discovery via organs-on-chips.Recapitulating maladaptive, multiscale remodeling of failing myocardium on a chip.Effects of shear stress pattern and magnitude on mesenchymal transformation and invasion of aortic valve endothelial cellsPotential drug targets for calcific aortic valve disease.Basic mechanisms of mitral regurgitation.A novel stretching platform for applications in cell and tissue mechanobiology.Metrics for assessing cytoskeletal orientational correlations and consistencyValvular interstitial cells suppress calcification of valvular endothelial cells.Pathophysiology of valvular heart disease.Mitral valve enlargement in chronic aortic regurgitation as a compensatory mechanism to prevent functional mitral regurgitation in the dilated left ventricle.Engineering challenges for instrumenting and controlling integrated organ-on-chip systems.Acute pergolide exposure stiffens engineered valve interstitial cell tissues and reduces contractility in vitro.Simulation of early calcific aortic valve disease in a 3D platform: A role for myofibroblast differentiation.The contribution of cellular mechanotransduction to cardiomyocyte form and function.Heterogeneous susceptibility of valve endothelial cells to mesenchymal transformation in response to TNFα.A microscale anisotropic biaxial cell stretching device for applications in mechanobiology.Heart Valve Biomechanics and Underlying MechanobiologyOrgan-on-a-Chip Systems: Microengineering to Biomimic Living Systems.Microfluidic Genipin Deposition Technique for Extended Culture of Micropatterned Vascular Muscular Thin FilmsEffect of aortic regurgitant jet direction on mitral valve leaflet remodeling: a real-time three-dimensional transesophageal echocardiography study.Valve interstitial cell contractile strength and metabolic state are dependent on its shapeDkk1 and MSX2-Wnt7b signaling reciprocally regulate the endothelial-mesenchymal transition in aortic endothelial cells.Actin and microtubules play distinct roles in governing the anisotropic deformation of cell nuclei in response to substrate strain.Mechanotransduction Mechanisms in Mitral Valve Physiology and Disease Pathogenesis.Regulation of valve interstitial cell homeostasis by mechanical deformation: implications for heart valve disease and surgical repair.Mitral Leaflet Changes Following Myocardial Infarction: Clinical Evidence for Maladaptive Valvular Remodeling.Controlling Differentiation of Stem Cells for Developing Personalized Organ-on-Chip Platforms.3D Miniaturization of Human Organs for Drug Discovery.Effect of Losartan on Mitral Valve Changes After Myocardial Infarction.Endothelial to mesenchymal transformation is induced by altered extracellular matrix in aortic valve endothelial cells.In situ heart valve tissue engineering: simple devices, smart materials, complex knowledge.Mitral Valve Adaptation to Isolated Annular Dilation: Insights Into the Mechanism of Atrial Functional Mitral Regurgitation.Elevated Serotonin Interacts with Angiotensin-II to Result in Altered Valve Interstitial Cell Contractility and Remodeling.
P2860
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P2860
Cyclic strain induces dual-mode endothelial-mesenchymal transformation of the cardiac valve.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Cyclic strain induces dual-mod ...... ormation of the cardiac valve.
@ast
Cyclic strain induces dual-mod ...... ormation of the cardiac valve.
@en
type
label
Cyclic strain induces dual-mod ...... ormation of the cardiac valve.
@ast
Cyclic strain induces dual-mod ...... ormation of the cardiac valve.
@en
prefLabel
Cyclic strain induces dual-mod ...... ormation of the cardiac valve.
@ast
Cyclic strain induces dual-mod ...... ormation of the cardiac valve.
@en
P2093
P2860
P356
P1476
Cyclic strain induces dual-mod ...... formation of the cardiac valve
@en
P2093
Anna Grosberg
Jill Wylie-Sears
Josue A Goss
Kartik Balachandran
Kevin Kit Parker
Patrick W Alford
Robert A Levine
P2860
P304
19943-19948
P356
10.1073/PNAS.1106954108
P407
P577
2011-11-28T00:00:00Z