Np95 is implicated in pericentromeric heterochromatin replication and in major satellite silencing - Wikidata - wikimedia - TriplyDB

Np95 is implicated in pericentromeric heterochromatin replication and in major satellite silencing

Np95 is implicated in pericentromeric heterochromatin replication and in major satellite silencing

http://www.wikidata.org/entity/Q35650852

about

ICBP90, a novel methyl K9 H3 binding protein linking protein ubiquitination with heterochromatin formation Recognition of multivalent histone states associated with heterochromatin by UHRF1 protein PHD finger recognition of unmodified histone H3R2 links UHRF1 to regulation of euchromatic gene expression Np95 interacts with de novo DNA methyltransferases, Dnmt3a and Dnmt3b, and mediates epigenetic silencing of the viral CMV promoter in embryonic stem cells UHRF1 plays a role in maintaining DNA methylation in mammalian cells Targeted DNA methylation by homology-directed repair in mammalian cells. Transcription reshapes methylation on the repaired gene.Modifiers and Readers of DNA Modifications and Their Impact on Genome Structure, Expression, and Stability in Disease NIRF/UHRF2 occupies a central position in the cell cycle network and allows coupling with the epigenetic landscape Partners in crime: The role of tandem modules in gene transcription UHRF1, a modular multi-domain protein, regulates replication-coupled crosstalk between DNA methylation and histone modifications Structural Insight into Coordinated Recognition of Trimethylated Histone H3 Lysine 9 (H3K9me3) by the Plant Homeodomain (PHD) and Tandem Tudor Domain (TTD) of UHRF1 (Ubiquitin-like, Containing PHD and RING Finger Domains, 1) Protein The PHD Finger of Human UHRF1 Reveals a New Subgroup of Unmethylated Histone H3 Tail Readers Conserved linker regions and their regulation determine multiple chromatin-binding modes of UHRF1 MBD4 interacts with and recruits USP7 to heterochromatic foci WDHD1 modulates the post-transcriptional step of the centromeric silencing pathway In Vitro Toxicity and Epigenotoxicity of Different Types of Ambient Particulate Matter Three SRA-domain methylcytosine-binding proteins cooperate to maintain global CpG methylation and epigenetic silencing in Arabidopsis.HAC stability in murine cells is influenced by nuclear localization and chromatin organization.Poly(ADP-ribose) polymerase 1 (PARP1) associates with E3 ubiquitin-protein ligase UHRF1 and modulates UHRF1 biological functions Functional dissection of the role of UHRF1 in the regulation of retinoblastoma methylome.UHRF1 is a genome caretaker that facilitates the DNA damage response to gamma-irradiation ORTH/VIM proteins that regulate DNA methylation are functional ubiquitin E3 ligases.H3K9me3-binding proteins are dispensable for SETDB1/H3K9me3-dependent retroviral silencing.An Allosteric Interaction Links USP7 to Deubiquitination and Chromatin Targeting of UHRF1.Histone demethylase JARID1C inactivation triggers genomic instability in sporadic renal cancer.Hemi-methylated DNA opens a closed conformation of UHRF1 to facilitate its histone recognition.The PHD domain of Np95 (mUHRF1) is involved in large-scale reorganization of pericentromeric heterochromatin Multivalent histone engagement by the linked tandem Tudor and PHD domains of UHRF1 is required for the epigenetic inheritance of DNA methylation.Mammalian DNA methyltransferases: a structural perspective.KDM2A represses transcription of centromeric satellite repeats and maintains the heterochromatic state The role of methyl-binding proteins in chromatin organization and epigenome maintenance.Control of genetic stability by a new heterochromatin compaction pathway involving the Tip60 histone acetyltransferase.Maintenance of Epigenetic Information.Heterochromatin and the molecular mechanisms of 'parent-of-origin' effects in animals.DNA damage regulates UHRF1 stability via the SCF(β-TrCP) E3 ligase.The SRA protein UHRF1 promotes epigenetic crosstalks and is involved in prostate cancer progression.UHRF1 coordinates peroxisome proliferator activated receptor gamma (PPARG) epigenetic silencing and mediates colorectal cancer progression.The multi-domain protein Np95 connects DNA methylation and histone modification.UHRF1 binds G9a and participates in p21 transcriptional regulation in mammalian cells.Uhrf1 and Dnmt1 are required for development and maintenance of the zebrafish lens

P2860

Q24298944-8C3A5C8B-4203-4528-9B74-B8DA5C8F72FF Q24299712-07068D4D-4582-46EC-8C7E-5EFF08025B86 Q24315922-5C62A93B-61E1-47C8-892C-F189B870F4FF Q24320076-F8839F84-AB0C-44DA-BD9E-E9B0BF2FAD83 Q24336152-A903D27D-19E1-4EC6-A8DC-A88888F278CA Q24613629-B016A70D-6221-4325-A30A-EC251465DF24 Q26742136-9F3A2CAB-8DDA-4E2E-B53B-22BB0ABDB5B6 Q26851503-469B7E25-3B1D-423B-ACBA-7C7F91FCCB38 Q26995208-E0644072-F30F-4EB8-8AB1-2CCC2F0F9C45 Q27653138-B12F6F39-0DBE-43BB-BB69-F21A48D3DAB7 Q27675158-C83BFFAF-9A62-4081-85C1-A5CB3C2AB1D8 Q27675643-8BC16E5D-5E5B-4022-84FA-7FDFCF3EFE4F Q28082738-113E742D-40C0-4AA8-889A-AAE37487D009 Q28250621-802B9A0D-98A2-4BFB-82D3-B1FA76088D1F Q28585218-4145A5E0-D205-4254-8061-D3EA8F7BE2C1 Q28596427-4FF8198A-ADE1-49BE-8B1B-5513801D5044 Q33360264-7C4F7528-2B39-429F-9EE4-F4FA76FFB220 Q33415674-595884DF-C1D2-4894-BDEC-8C5731D6FA59 Q33718499-25D1028F-9AB5-430C-8B07-F6DA611C0679 Q33889243-08B8D101-AE9F-4B09-BCDD-1BDAF15501B1 Q34036281-C3423360-F5C3-4CAD-88A1-1AFEE63742B1 Q34277667-DEF11346-8257-438A-9328-B130C5DDE778 Q35203648-77AFFF68-1E29-472C-9D40-775BDE213F80 Q36021816-67583E10-3D69-49CA-B55B-79EDF1E4E83D Q36335903-8CDCD133-E300-41C3-8F87-3CC6CC10CF20 Q36768848-F456052C-64FF-4500-A12A-50CC5C0F0741 Q36796852-0030952C-C7EF-4FF9-94EA-CCC4E051F696 Q36948989-2E2D5D2A-161E-40E4-B900-F64AA44AE27F Q37002199-6517EAE4-B9BF-43EE-B669-623AF91C1528 Q37085752-770984DA-2280-4505-8BBA-5DB99FE1963E Q37970067-4619FDC7-A50B-46E7-861D-D53C90CA597C Q38370055-2FA65CC9-8EEE-4D09-B728-2FFA38C52DB4 Q38824303-A6D21346-B456-4306-A37D-76992E30EC1B Q39038126-E74AAC0B-5836-4FD2-9722-2C0688F43F96 Q39214600-15AE0F19-183F-44B0-8A09-C89E64208478 Q39397231-1803E2BF-4F44-4D93-B0A0-138F537A4B40 Q39404751-78307CC8-08B3-4424-ACD5-5FFAA3EB9FA6 Q39760453-F0F5E873-4120-407F-B832-F0584ADBD902 Q39908724-C96D00FE-A964-4FC2-B4B7-4B2D7B897149 Q42573684-D8CA653D-59B2-466C-8BDD-26E1A8BD9E1D

P2860

Np95 is implicated in pericentromeric heterochromatin replication and in major satellite silencing

http://www.wikidata.org/entity/Q35650852

description

2006 nî lūn-bûn

@nan

2006年の論文

@ja

2006年論文

@yue

2006年論文

@zh-hant

2006年論文

@zh-hk

2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

@wuu

2006年论文

@zh

2006年论文

@zh-cn

name

Np95 is implicated in pericent ...... d in major satellite silencing

@ast

Np95 is implicated in pericent ...... d in major satellite silencing

@en

type

label

Np95 is implicated in pericent ...... d in major satellite silencing

@ast

Np95 is implicated in pericent ...... d in major satellite silencing

@en

prefLabel

Np95 is implicated in pericent ...... d in major satellite silencing

@ast

Np95 is implicated in pericent ...... d in major satellite silencing

@en

P1433

Q35650852-0FA7E5C3-4D01-441A-A438-7D2A02F4929A

P1476

Q35650852-40426534-1E6F-42DF-8026-B2337E17BE33

P2093

Q35650852-11CD5995-EFD6-4374-8DC4-F5B85FDBC0AB

Q35650852-3913E974-F238-4161-8EF7-A3244AADD8F7

Q35650852-8E743314-6294-4560-8AE0-FC6D4D9BA475

Q35650852-C5770DFD-3010-4C50-9149-B28D7ED5BD11

Q35650852-D6769D6A-E74A-4782-BAF0-BB1C54C28E03

P2860

Q35650852-0B75B20E-EFAE-4BF4-A73E-B8168FB75140

Q35650852-12617968-AEE4-442A-B998-3A18D2813814

Q35650852-12D90C0C-D80A-4788-AE92-85744EE6A35B

Q35650852-13D5DD18-EDA0-4E71-88FE-CED066072194

Q35650852-2265901E-D138-40A0-8932-6FC09A8972E8

Q35650852-263A8644-7DE0-4374-B8D2-ADB5565C14BF

Q35650852-26929851-5B24-4231-A402-84E63A143248

Q35650852-35448D28-F03D-4316-8300-7D59651B8D0D

Q35650852-38E12613-327D-42E2-8CF2-F2E1F1A163F9

Q35650852-39EA6271-3786-4CB6-BA98-55A16756AAA2

P304

Q35650852-943F667B-9A1B-4F22-BEBA-1987CCFB2FF2

P31

Q35650852-9CA53B33-B782-470D-8001-B3CE719F9E7F

P356

Q35650852-64BCEE9B-9B3B-4B7C-BED3-E6FE8D9611FC

P433

Q35650852-3D92A2E9-6196-4582-ABC0-9EFB4EAB5644

P478

Q35650852-2C3394E9-07C7-49C9-B4C5-6B08397F14C3

P50

Q35650852-B8CEBC97-C525-4A64-AF8D-BD9EC93B95C6

P577

Q35650852-4EC1A90C-BACE-4640-8805-BA96F1837E84

P698

Q35650852-2F84EB29-7BB4-4F1C-A925-96504CD7436A

P932

Q35650852-B0FF80D6-9857-4B42-896F-9C9DC581E4D0

P356

MBC.E06-09-0874

P1433

Molecular Biology of the Cell

P1476

Np95 is implicated in pericent ...... d in major satellite silencing

@en

P2093

Christian Pistore

http://www.w3.org/2001/XMLSchema#string

Daniela Pecoraro

http://www.w3.org/2001/XMLSchema#string

Diego Negri

http://www.w3.org/2001/XMLSchema#string

Ian Marc Bonapace

http://www.w3.org/2001/XMLSchema#string

Lisa Cantarini

http://www.w3.org/2001/XMLSchema#string

P2860

ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain

Nucleosome assembly by a complex of CAF-1 and acetylated histones H3/H4

Np95 is a histone-binding protein endowed with ubiquitin ligase activity

Longevity regulation in Saccharomyces cerevisiae: linking metabolism, genome stability, and heterochromatin

Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin

The retinoblastoma gene and its product are targeted by ICBP90: a key mechanism in the G1/S transition during the cell cycle

Cloning and mapping of Np95 gene which encodes a novel nuclear protein associated with cell proliferation

Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing

Heterochromatin and epigenetic control of gene expression

Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability

P304

1098-1106

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1091/MBC.E06-09-0874

http://www.w3.org/2001/XMLSchema#string

P433

3

http://www.w3.org/2001/XMLSchema#string

P478

18

http://www.w3.org/2001/XMLSchema#string

P50

P577

2006-12-20T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

17182844

http://www.w3.org/2001/XMLSchema#string

P932

1805105

http://www.w3.org/2001/XMLSchema#string