Actin depletion initiates events leading to granule secretion at the immunological synapse. - Wikidata - wikimedia - TriplyDB

Actin depletion initiates events leading to granule secretion at the immunological synapse.

Actin depletion initiates events leading to granule secretion at the immunological synapse.

http://www.wikidata.org/entity/Q35662889

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New Insights into How Trafficking Regulates T Cell Receptor Signaling Underground Adaptation to a Hostile Environment: Acute Myeloid Leukemia vs. Natural Killer Cells Biophysical Aspects of T Lymphocyte Activation at the Immune Synapse Comparative Anatomy of Phagocytic and Immunological Synapses T Lymphocyte Migration: An Action Movie Starring the Actin and Associated Actors.Cytotoxic granule secretion by lymphocytes and its link to immune homeostasis PI3Kδ promotes CD4(+) T-cell interactions with antigen-presenting cells by increasing LFA-1 binding to ICAM-1.Actin nucleation at the centrosome controls lymphocyte polarity.A major secretory defect of tumour-infiltrating T lymphocytes due to galectin impairing LFA-1-mediated synapse completion.T cell activation requires force generation NDR1-Dependent Regulation of Kindlin-3 Controls High-Affinity LFA-1 Binding and Immune Synapse Organization.eNOS S-nitrosylates β-actin on Cys374 and regulates PKC-θ at the immune synapse by impairing actin binding to profilin-1.A cytoskeletal clutch mediates cellular force transmission in a soft, three-dimensional extracellular matrix.Cytotoxic T Cells Use Mechanical Force to Potentiate Target Cell Killing In Vivo Killing Capacity of Cytotoxic T Cells Is Limited and Involves Dynamic Interactions and T Cell Cooperativity.Calcium influx through CRAC channels controls actin organization and dynamics at the immune synapse.NK cells converge lytic granules to promote cytotoxicity and prevent bystander killing.Contractile actomyosin arcs promote the activation of primary mouse T cells in a ligand-dependent manner.Distinct patterns of cytolytic T-cell activation by different tumour cells revealed by Ca2+ signalling and granule mobilization.Zinc finger E-box binding homeobox-1 (Zeb1) drives anterograde lysosome trafficking and tumor cell invasion via upregulation of Na+/H+ Exchanger-1 (NHE1).Origins of the cytolytic synapse.Regulation of T cell signalling by membrane lipids.Mechanical Communication at the Immunological Synapse.The reinvention of twentieth century microscopy for three-dimensional imaging.Natural killer cell granules converge to avoid collateral damage.Quantitative Imaging Approaches to Study the CAR Immunological Synapse.Cytoskeletal control of B cell responses to antigens.NFATc1 controls the cytotoxicity of CD8+ T cells.Mechanosensing drives acuity of αβ T-cell recognition.Cortical actin recovery at the immunological synapse leads to termination of lytic granule secretion in cytotoxic T lymphocytes.Live-Cell Super-resolution Reveals F-Actin and Plasma Membrane Dynamics at the T Cell Synapse.Measurement of Lytic Granule Convergence After Formation of an NK Cell Immunological Synapse.Inducible T Cell Kinase Regulates the Acquisition of Cytolytic Capacity and Degranulation in CD8+ CTLs.Mother Centriole Distal Appendages Mediate Centrosome Docking at the Immunological Synapse and Reveal Mechanistic Parallels with Ciliogenesis Cytoskeletal actin dynamics shape a ramifying actin network underpinning immunological synapse formation.Orchestrating Lymphocyte Polarity in Cognate Immune Cell-Cell Interactions.Lysosome trafficking is necessary for EGF-driven invasion and is regulated by p38 MAPK and Na+/H+ exchangers.The pro-oxidative drug WF-10 inhibits serial killing by primary human cytotoxic T-cells.Dynamic microtubules regulate cellular contractility during T-cell activation.An actin cytoskeletal barrier inhibits lytic granule release from Natural Killer cells in Chediak-Higashi syndrome.

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Actin depletion initiates events leading to granule secretion at the immunological synapse.

http://www.wikidata.org/entity/Q35662889

description

2015 nî lūn-bûn

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2015年の論文

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2015年论文

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2015年论文

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2015年论文

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Actin depletion initiates even ...... at the immunological synapse.

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Actin depletion initiates even ...... at the immunological synapse.

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Actin depletion initiates even ...... at the immunological synapse.

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Actin depletion initiates even ...... at the immunological synapse.

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Actin depletion initiates even ...... at the immunological synapse.

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Actin depletion initiates even ...... at the immunological synapse.

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Actin depletion initiates even ...... at the immunological synapse.

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Alex T Ritter

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C Gawden-Bone

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Jane C Stinchcombe

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Liang Gao

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Michael W Davidson

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N M G Dieckmann

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Schuyler van Engelenburg

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Wesley Legant

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Yukako Asano

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P2860

Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling.

Multiple roles for the actin cytoskeleton during regulated exocytosis

Remodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopy

Natural killer cell lytic granule secretion occurs through a pervasive actin network at the immune synapse

Phosphatidylinositol 4,5-bisphosphate functions as a second messenger that regulates cytoskeleton-plasma membrane adhesion.

Staging and resetting T cell activation in SMACs

Three-dimensional segregation of supramolecular activation clusters in T cells

Lifeact: a versatile marker to visualize F-actin

T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster.

Fas ligand is targeted to secretory lysosomes via a proline-rich domain in its cytoplasmic tail.

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