Small-Molecule-Mediated Degradation of the Androgen Receptor through Hydrophobic Tagging
about
A sting in the tail: the N-terminal domain of the androgen receptor as a drug targetInduced protein degradation: an emerging drug discovery paradigm.Chemical approaches to targeted protein degradation through modulation of the ubiquitin-proteasome pathwayDegradation of Akt using protein-catalyzed capture agents.Discovery of a Structurally Unique Small Molecule that Inhibits Protein SynthesisTargeted Protein Degradation by Small Molecules.Waste disposal-An attractive strategy for cancer therapy.Targeted protein knockdown using small molecule degraders.Targeted Protein Degradation: from Chemical Biology to Drug Discovery.pSILAC mass spectrometry reveals ZFP91 as IMiD-dependent substrate of the CRL4CRBN ubiquitin ligase.Boc3Arg-Linked Ligands Induce Degradation by Localizing Target Proteins to the 20S Proteasome.Design, synthesis, and evaluation of the antiproliferative activity of hydantoin-derived antiandrogen-genistein conjugates.Enzalutamide and blocking androgen receptor in advanced prostate cancer: lessons learnt from the history of drug development of antiandrogens.Androgen receptor degradation by the proteolysis-targeting chimera ARCC-4 outperforms enzalutamide in cellular models of prostate cancer drug resistanceSmall-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs
P2860
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P2860
Small-Molecule-Mediated Degradation of the Androgen Receptor through Hydrophobic Tagging
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Small-Molecule-Mediated Degradation of the Androgen Receptor through Hydrophobic Tagging
@ast
Small-Molecule-Mediated Degradation of the Androgen Receptor through Hydrophobic Tagging
@en
type
label
Small-Molecule-Mediated Degradation of the Androgen Receptor through Hydrophobic Tagging
@ast
Small-Molecule-Mediated Degradation of the Androgen Receptor through Hydrophobic Tagging
@en
prefLabel
Small-Molecule-Mediated Degradation of the Androgen Receptor through Hydrophobic Tagging
@ast
Small-Molecule-Mediated Degradation of the Androgen Receptor through Hydrophobic Tagging
@en
P2093
P2860
P356
P1476
Small-Molecule-Mediated Degradation of the Androgen Receptor through Hydrophobic Tagging
@en
P2093
Anke G Roth
Carly S Cox
Craig M Crews
D Blake Stagg
Dennis L Buckley
Donald P McDonnell
Hyun Seop Tae
Jeffrey L Gustafson
John D Norris
John Hines
P2860
P304
P356
10.1002/ANIE.201503720
P407
P577
2015-06-17T00:00:00Z