Natural diterpenoid compound elevates expression of Bim protein, which interacts with antiapoptotic protein Bcl-2, converting it to proapoptotic Bax-like molecule.

Natural diterpenoid compound elevates expression of Bim protein, which interacts with antiapoptotic protein Bcl-2, converting it to proapoptotic Bax-like molecule.

Item
http://www.wikidata.org/entity/Q35668914
A small natural molecule promotes mitochondrial fusion through inhibition of the deubiquitinase USP30Phosphorylation of Rad9 at serine 328 by cyclin A-Cdk2 triggers apoptosis via interfering Bcl-xLA New Fungal Diterpene Induces VDAC1-dependent Apoptosis in Bax/Bak-deficient Cells.Mitochondrial ATF2 translocation contributes to apoptosis induction and BRAF inhibitor resistance in melanoma through the interaction of Bim with VDAC1.Reduction of myeloid-derived suppressor cells and lymphoma growth by a natural triterpenoid.After embedding in membranes antiapoptotic Bcl-XL protein binds both Bcl-2 homology region 3 and helix 1 of proapoptotic Bax protein to inhibit apoptotic mitochondrial permeabilization.Mitofusins: ubiquitylation promotes fusion.Molecular elucidation of a new allelic variation at the Sg-5 gene associated with the absence of group A saponins in wild soybean.UMI-77 primes glioma cells for TRAIL-induced apoptosis by unsequestering Bim and Bak from Mcl-1.A bio-inspired synthetic route to the core ring systems of Spiraea atisine-type diterpenoid alkaloids and related diterpenes.Collective Total Syntheses of Atisane-Type Diterpenes and Atisine-Type Diterpenoid Alkaloids: (±)-Spiramilactone B, (±)-Spiraminol, (±)-Dihydroajaconine, and (±)-Spiramines C and D.17β-estradiol impedes Bax-involved mitochondrial apoptosis of retinal nerve cells induced by oxidative damage via the phosphatidylinositol 3-kinase/Akt signal pathway.
P2860

Natural diterpenoid compound elevates expression of Bim protein, which interacts with antiapoptotic protein Bcl-2, converting it to proapoptotic Bax-like molecule.

Item
http://www.wikidata.org/entity/Q35668914
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Natural diterpenoid compound e ...... roapoptotic Bax-like molecule.
@ast
Natural diterpenoid compound e ...... roapoptotic Bax-like molecule.
@en
type
label
Natural diterpenoid compound e ...... roapoptotic Bax-like molecule.
@ast
Natural diterpenoid compound e ...... roapoptotic Bax-like molecule.
@en
prefLabel
Natural diterpenoid compound e ...... roapoptotic Bax-like molecule.
@ast
Natural diterpenoid compound e ...... roapoptotic Bax-like molecule.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932
P356
P1433
P1476
Natural diterpenoid compound e ...... proapoptotic Bax-like molecule
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932