about
Guidelines for the use and interpretation of assays for monitoring autophagyHuman Bop is a novel BH3-only member of the Bcl-2 protein familyReceptor-mediated mitophagy in yeast and mammalian systemsParkin promotes proteasomal degradation of p62: implication of selective vulnerability of neuronal cells in the pathogenesis of Parkinson's diseaseMulti-patterned dynamics of mitochondrial fission and fusion in a living cellIdentification of the protein-protein contact site and interaction mode of human VDAC1 with Bcl-2 family proteinsA systems biology understanding of the synergistic effects of arsenic sulfide and Imatinib in BCR/ABL-associated leukemiaMice deficient in Epg5 exhibit selective neuronal vulnerability to degenerationMorphine induces Beclin 1- and ATG5-dependent autophagy in human neuroblastoma SH-SY5Y cells and in the rat hippocampusMechanical stretch induces mitochondria-dependent apoptosis in neonatal rat cardiomyocytes and G2/M accumulation in cardiac fibroblastsSuperoxide flashes: early mitochondrial signals for oxidative stress-induced apoptosis.Identification of genes regulated by Wnt/beta-catenin pathway and involved in apoptosis via microarray analysis.Role of Apo2L/TRAIL and Bcl-2-family proteins in apoptosis of multiple myeloma.RNF185, a novel mitochondrial ubiquitin E3 ligase, regulates autophagy through interaction with BNIP1.Essential role of the voltage-dependent anion channel (VDAC) in mitochondrial permeability transition pore opening and cytochrome c release induced by arsenic trioxide.The Bcl-2 homology domain 3 mimetic gossypol induces both Beclin 1-dependent and Beclin 1-independent cytoprotective autophagy in cancer cellsProteolytic cleavage of cyclin E leads to inactivation of associated kinase activity and amplification of apoptosis in hematopoietic cells.Apo2L/TRAIL and Bcl-2-related proteins regulate type I interferon-induced apoptosis in multiple myelomaThe BCL2L1 and PGAM5 axis defines hypoxia-induced receptor-mediated mitophagy.Parkin ubiquitinates Drp1 for proteasome-dependent degradation: implication of dysregulated mitochondrial dynamics in Parkinson diseaseNatural diterpenoid compound elevates expression of Bim protein, which interacts with antiapoptotic protein Bcl-2, converting it to proapoptotic Bax-like molecule.Cysteine 62 of Bax is critical for its conformational activation and its proapoptotic activity in response to H2O2-induced apoptosisCaspase cleavage of cytochrome c1 disrupts mitochondrial function and enhances cytochrome c release.Central role of mitofusin 2 in autophagosome-lysosome fusion in cardiomyocytes.Appoptosin is a novel pro-apoptotic protein and mediates cell death in neurodegeneration.Zyxin-Siah2-Lats2 axis mediates cooperation between Hippo and TGF-β signalling pathwaysMitophagy receptor FUNDC1 regulates mitochondrial dynamics and mitophagy.Parkin deficiency contributes to pancreatic tumorigenesis by inducing spindle multipolarity and misorientation.Endophilin B2 promotes inner mitochondrial membrane degradation by forming heterodimers with Endophilin B1 during mitophagy.Establishment of a human colorectal cancer cell line P6C with stem cell properties and resistance to chemotherapeutic drugs.Hypoxic mitophagy regulates mitochondrial quality and platelet activation and determines severity of I/R heart injury.Regulation of mATG9 trafficking by Src- and ULK1-mediated phosphorylation in basal and starvation-induced autophagy.Molecular signaling toward mitophagy and its physiological significance.Hypoxia activation of mitophagy and its role in disease pathogenesis.Selective removal of mitochondria via mitophagy: distinct pathways for different mitochondrial stresses.Drp1 is dispensable for mitochondria biogenesis in induction to pluripotency but required for differentiation of embryonic stem cells.CD44-positive cancer stem cells expressing cellular prion protein contribute to metastatic capacity in colorectal cancer.Parkin regulates paclitaxel sensitivity in breast cancer via a microtubule-dependent mechanism.Cytotoxic activities of new jadomycin derivatives.Osteopontin, a possible modulator of cancer stem cells and their malignant niche.
P50
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P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Quan Chen
@ast
Quan Chen
@en
Quan Chen
@es
Quan Chen
@nl
Quan Chen
@sl
type
label
Quan Chen
@ast
Quan Chen
@en
Quan Chen
@es
Quan Chen
@nl
Quan Chen
@sl
prefLabel
Quan Chen
@ast
Quan Chen
@en
Quan Chen
@es
Quan Chen
@nl
Quan Chen
@sl
P106
P31
P496
0000-0001-7539-8728